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CCAR1 (cell division cycle and apoptosis regulator 1)

Identity

Alias_symbol (synonym)FLJ10590
CARP-1
CARP1
Other alias-
HGNC (Hugo) CCAR1
LocusID (NCBI) 55749
Atlas_Id 47696
Location 10q21.3  [Link to chromosome band 10q21]
Location_base_pair Starts at 68721144 and ends at 68792377 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CCAR1 (10q21.3) / BAZ1A (14q13.1)CCAR1 (10q21.3) / CCAR1 (10q21.3)CCAR1 (10q21.3) / ONECUT1 (15q21.3)
CCAR1 (10q21.3) / PAWR (12q21.2)MTR (1q43) / CCAR1 (10q21.3)TET1 (10q21.3) / CCAR1 (10q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  TET1/CCAR1 (10q21)


External links

Nomenclature
HGNC (Hugo)CCAR1   24236
Cards
Entrez_Gene (NCBI)CCAR1  55749  cell division cycle and apoptosis regulator 1
Aliases
GeneCards (Weizmann)CCAR1
Ensembl hg19 (Hinxton)ENSG00000060339 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000060339 [Gene_View]  ENSG00000060339 [Sequence]  chr10:68721144-68792377 [Contig_View]  CCAR1 [Vega]
ICGC DataPortalENSG00000060339
TCGA cBioPortalCCAR1
AceView (NCBI)CCAR1
Genatlas (Paris)CCAR1
WikiGenes55749
SOURCE (Princeton)CCAR1
Genetics Home Reference (NIH)CCAR1
Genomic and cartography
GoldenPath hg38 (UCSC)CCAR1  -     chr10:68721144-68792377 +  10q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CCAR1  -     10q21.3   [Description]    (hg19-Feb_2009)
EnsemblCCAR1 - 10q21.3 [CytoView hg19]  CCAR1 - 10q21.3 [CytoView hg38]
Mapping of homologs : NCBICCAR1 [Mapview hg19]  CCAR1 [Mapview hg38]
OMIM612569   
Gene and transcription
Genbank (Entrez)AF465616 AK000741 AK001701 AK023438 AK122871
RefSeq transcript (Entrez)NM_001282959 NM_001282960 NM_018237
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CCAR1
Cluster EST : UnigeneHs.49853 [ NCBI ]
CGAP (NCI)Hs.49853
Alternative Splicing GalleryENSG00000060339
Gene ExpressionCCAR1 [ NCBI-GEO ]   CCAR1 [ EBI - ARRAY_EXPRESS ]   CCAR1 [ SEEK ]   CCAR1 [ MEM ]
Gene Expression Viewer (FireBrowse)CCAR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55749
GTEX Portal (Tissue expression)CCAR1
Human Protein AtlasENSG00000060339-CCAR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IX12   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IX12  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IX12
Splice isoforms : SwissVarQ8IX12
PhosPhoSitePlusQ8IX12
Domaine pattern : Prosite (Expaxy)SAP (PS50800)   
Domains : Interpro (EBI)CCAR1/CCAR2    DBC1/CARP1_inactive_NUDIX_dom    EF-hand-dom_pair    NA-bd_OB-fold    S1-like_RNA-bd_dom    SAP_dom    SAP_dom_sf   
Domain families : Pfam (Sanger)DBC1 (PF14443)    S1-like (PF14444)    SAP (PF02037)   
Domain families : Pfam (NCBI)pfam14443    pfam14444    pfam02037   
Domain families : Smart (EMBL)DBC1 (SM01122)  SAP (SM00513)  
Conserved Domain (NCBI)CCAR1
DMDM Disease mutations55749
Blocks (Seattle)CCAR1
SuperfamilyQ8IX12
Human Protein Atlas [tissue]ENSG00000060339-CCAR1 [tissue]
Peptide AtlasQ8IX12
HPRD10811
IPIIPI00217357   IPI00939119   IPI01013354   IPI01012894   IPI01009122   IPI01011477   IPI01011002   IPI01010531   IPI01010062   IPI01009762   IPI01010326   IPI01015257   IPI01009531   IPI01010858   
Protein Interaction databases
DIP (DOE-UCLA)Q8IX12
IntAct (EBI)Q8IX12
FunCoupENSG00000060339
BioGRIDCCAR1
STRING (EMBL)CCAR1
ZODIACCCAR1
Ontologies - Pathways
QuickGOQ8IX12
Ontology : AmiGOmRNA splicing, via spliceosome  RNA polymerase II distal enhancer sequence-specific DNA binding  transcription coactivator activity  transcription coactivator activity  transcription corepressor activity  RNA binding  protein binding  nucleus  nucleoplasm  regulation of transcription, DNA-templated  apoptotic process  cell cycle  positive regulation of cell proliferation  positive regulation of cell migration  nuclear receptor transcription coactivator activity  nuclear receptor transcription coactivator activity  perinuclear region of cytoplasm  negative regulation of nucleic acid-templated transcription  positive regulation of nucleic acid-templated transcription  
Ontology : EGO-EBImRNA splicing, via spliceosome  RNA polymerase II distal enhancer sequence-specific DNA binding  transcription coactivator activity  transcription coactivator activity  transcription corepressor activity  RNA binding  protein binding  nucleus  nucleoplasm  regulation of transcription, DNA-templated  apoptotic process  cell cycle  positive regulation of cell proliferation  positive regulation of cell migration  nuclear receptor transcription coactivator activity  nuclear receptor transcription coactivator activity  perinuclear region of cytoplasm  negative regulation of nucleic acid-templated transcription  positive regulation of nucleic acid-templated transcription  
NDEx NetworkCCAR1
Atlas of Cancer Signalling NetworkCCAR1
Wikipedia pathwaysCCAR1
Orthology - Evolution
OrthoDB55749
GeneTree (enSembl)ENSG00000060339
Phylogenetic Trees/Animal Genes : TreeFamCCAR1
HOVERGENQ8IX12
HOGENOMQ8IX12
Homologs : HomoloGeneCCAR1
Homology/Alignments : Family Browser (UCSC)CCAR1
Gene fusions - Rearrangements
Fusion : MitelmanTET1/CCAR1 [10q21.3/10q21.3]  [t(10;10)(q21;q21)]  
Fusion : QuiverCCAR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCAR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCAR1
dbVarCCAR1
ClinVarCCAR1
1000_GenomesCCAR1 
Exome Variant ServerCCAR1
ExAC (Exome Aggregation Consortium)ENSG00000060339
GNOMAD BrowserENSG00000060339
Varsome BrowserCCAR1
Genetic variants : HAPMAP55749
Genomic Variants (DGV)CCAR1 [DGVbeta]
DECIPHERCCAR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCCAR1 
Mutations
ICGC Data PortalCCAR1 
TCGA Data PortalCCAR1 
Broad Tumor PortalCCAR1
OASIS PortalCCAR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCAR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCAR1
intOGen PortalCCAR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCAR1
DgiDB (Drug Gene Interaction Database)CCAR1
DoCM (Curated mutations)CCAR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCAR1 (select a term)
intoGenCCAR1
Cancer3DCCAR1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612569   
Orphanet
DisGeNETCCAR1
MedgenCCAR1
Genetic Testing Registry CCAR1
NextProtQ8IX12 [Medical]
TSGene55749
GENETestsCCAR1
Target ValidationCCAR1
Huge Navigator CCAR1 [HugePedia]
snp3D : Map Gene to Disease55749
BioCentury BCIQCCAR1
ClinGenCCAR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55749
Chemical/Pharm GKB GenePA134920227
Clinical trialCCAR1
Miscellaneous
canSAR (ICR)CCAR1 (select the gene name)
Probes
Litterature
PubMed61 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCAR1
EVEXCCAR1
GoPubMedCCAR1
iHOPCCAR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 10:56:00 CET 2018

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