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CCL22 (C-C motif chemokine ligand 22)

Identity

Alias_namesSCYA22
small inducible cytokine subfamily A (Cys-Cys), member 22
chemokine (C-C motif) ligand 22
Alias_symbol (synonym)MDC
STCP-1
ABCD-1
DC/B-CK
A-152E5.1
MGC34554
Other alias
HGNC (Hugo) CCL22
LocusID (NCBI) 6367
Atlas_Id 46211
Location 16q13  [Link to chromosome band 16q13]
Location_base_pair Starts at 57392695 and ends at 57400102 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
TIPRL (1q24.2) / CCL22 (16q13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CCL22   10621
Cards
Entrez_Gene (NCBI)CCL22  6367  C-C motif chemokine ligand 22
AliasesA-152E5.1; ABCD-1; DC/B-CK; MDC; 
SCYA22; STCP-1
GeneCards (Weizmann)CCL22
Ensembl hg19 (Hinxton)ENSG00000102962 [Gene_View]  chr16:57392695-57400102 [Contig_View]  CCL22 [Vega]
Ensembl hg38 (Hinxton)ENSG00000102962 [Gene_View]  chr16:57392695-57400102 [Contig_View]  CCL22 [Vega]
ICGC DataPortalENSG00000102962
TCGA cBioPortalCCL22
AceView (NCBI)CCL22
Genatlas (Paris)CCL22
WikiGenes6367
SOURCE (Princeton)CCL22
Genetics Home Reference (NIH)CCL22
Genomic and cartography
GoldenPath hg19 (UCSC)CCL22  -     chr16:57392695-57400102 +  16q13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CCL22  -     16q13   [Description]    (hg38-Dec_2013)
EnsemblCCL22 - 16q13 [CytoView hg19]  CCL22 - 16q13 [CytoView hg38]
Mapping of homologs : NCBICCL22 [Mapview hg19]  CCL22 [Mapview hg38]
OMIM602957   
Gene and transcription
Genbank (Entrez)AK311970 BC027952 DA815965 DB154173 DQ890922
RefSeq transcript (Entrez)NM_002990
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)CCL22
Cluster EST : UnigeneHs.534347 [ NCBI ]
CGAP (NCI)Hs.534347
Alternative Splicing GalleryENSG00000102962
Gene ExpressionCCL22 [ NCBI-GEO ]   CCL22 [ EBI - ARRAY_EXPRESS ]   CCL22 [ SEEK ]   CCL22 [ MEM ]
Gene Expression Viewer (FireBrowse)CCL22 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6367
GTEX Portal (Tissue expression)CCL22
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00626   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00626  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00626
Splice isoforms : SwissVarO00626
PhosPhoSitePlusO00626
Domaine pattern : Prosite (Expaxy)SMALL_CYTOKINES_CC (PS00472)   
Domains : Interpro (EBI)CCL22    Chemokine_CC_CS    Chemokine_IL8-like_dom   
Domain families : Pfam (Sanger)IL8 (PF00048)   
Domain families : Pfam (NCBI)pfam00048   
Domain families : Smart (EMBL)SCY (SM00199)  
Conserved Domain (NCBI)CCL22
DMDM Disease mutations6367
Blocks (Seattle)CCL22
SuperfamilyO00626
Human Protein AtlasENSG00000102962
Peptide AtlasO00626
HPRD04263
IPIIPI00299224   
Protein Interaction databases
DIP (DOE-UCLA)O00626
IntAct (EBI)O00626
FunCoupENSG00000102962
BioGRIDCCL22
STRING (EMBL)CCL22
ZODIACCCL22
Ontologies - Pathways
QuickGOO00626
Ontology : AmiGOmonocyte chemotaxis  extracellular region  extracellular space  chemotaxis  inflammatory response  immune response  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  response to virus  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Ontology : EGO-EBImonocyte chemotaxis  extracellular region  extracellular space  chemotaxis  inflammatory response  immune response  signal transduction  G-protein coupled receptor signaling pathway  cell-cell signaling  chemokine activity  response to virus  neutrophil chemotaxis  positive regulation of GTPase activity  CCR chemokine receptor binding  lymphocyte chemotaxis  chemokine-mediated signaling pathway  positive regulation of ERK1 and ERK2 cascade  cellular response to interferon-gamma  cellular response to interleukin-1  cellular response to tumor necrosis factor  
Pathways : KEGGCytokine-cytokine receptor interaction    Chemokine signaling pathway   
NDEx NetworkCCL22
Atlas of Cancer Signalling NetworkCCL22
Wikipedia pathwaysCCL22
Orthology - Evolution
OrthoDB6367
GeneTree (enSembl)ENSG00000102962
Phylogenetic Trees/Animal Genes : TreeFamCCL22
HOVERGENO00626
HOGENOMO00626
Homologs : HomoloGeneCCL22
Homology/Alignments : Family Browser (UCSC)CCL22
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCCL22 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CCL22
dbVarCCL22
ClinVarCCL22
1000_GenomesCCL22 
Exome Variant ServerCCL22
ExAC (Exome Aggregation Consortium)CCL22 (select the gene name)
Genetic variants : HAPMAP6367
Genomic Variants (DGV)CCL22 [DGVbeta]
DECIPHER (Syndromes)16:57392695-57400102  ENSG00000102962
CONAN: Copy Number AnalysisCCL22 
Mutations
ICGC Data PortalCCL22 
TCGA Data PortalCCL22 
Broad Tumor PortalCCL22
OASIS PortalCCL22 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCCL22  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCCL22
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CCL22
DgiDB (Drug Gene Interaction Database)CCL22
DoCM (Curated mutations)CCL22 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CCL22 (select a term)
intoGenCCL22
Cancer3DCCL22(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602957   
Orphanet
MedgenCCL22
Genetic Testing Registry CCL22
NextProtO00626 [Medical]
TSGene6367
GENETestsCCL22
Huge Navigator CCL22 [HugePedia]
snp3D : Map Gene to Disease6367
BioCentury BCIQCCL22
ClinGenCCL22
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6367
Chemical/Pharm GKB GenePA35553
Clinical trialCCL22
Miscellaneous
canSAR (ICR)CCL22 (select the gene name)
Probes
Litterature
PubMed96 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCCL22
EVEXCCL22
GoPubMedCCL22
iHOPCCL22
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:59:05 CET 2017

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