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CGA (glycoprotein hormones, alpha polypeptide)

Identity

Other namesCG-ALPHA
FSHA
GPHA1
GPHa
HCG
LHA
TSHA
HGNC (Hugo) CGA
LocusID (NCBI) 1081
Location 6q14.3
Location_base_pair Starts at 87795216 and ends at 87804865 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CGA   1885
Entrez_Gene (NCBI)CGA  1081  glycoprotein hormones, alpha polypeptide
Cards
GeneCards (Weizmann)CGA
Ensembl (Hinxton)ENSG00000135346 [Gene_View]  chr6:87795216-87804865 [Contig_View]  CGA [Vega]
AceView (NCBI)CGA
Genatlas (Paris)CGA
SOURCE (Stanford)NM_000735 NM_001252383
Genomic and cartography
GoldenPath (UCSC)CGA  -  6q14.3   chr6:87795216-87804865 -  6q14.3   [Description]    (hg19-Feb_2009)
EnsemblCGA - 6q14.3 [CytoView]
Mapping of homologs : NCBICGA [Mapview]
OMIM118850   
Gene and transcription
Genbank (Entrez)AB019569 AI200485 AK311972 BC010957 BC020782
RefSeq transcript (SRS)NM_000735 NM_001252383
RefSeq transcript (Entrez)NM_000735 NM_001252383
RefSeq genomic (SRS)AC_000138 NC_000006 NC_018917 NT_007299 NW_001838987 NW_004078027
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NT_007299 NW_001838987 NW_004078027
Consensus coding sequences : CCDS (NCBI)CGA
Cluster EST : UnigeneHs.119689 [ SRS ] Hs.119689 [ NCBI ]
CGAP (NCI)Hs.119689
Alternative Splicing : Fast-db (Paris)GSHG0026764
Alternative Splicing GalleryENSG00000135346
Gene ExpressionCGA [ NCBI-GEO ]   CGA [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01215 (SRS) P01215 (Uniprot)
NextProtP01215
With graphics : InterProP01215
Splice isoforms : SwissVarP01215(Swissvar)
Domaine pattern : Prosite (SRS)GLYCO_HORMONE_ALPHA_1 (PS00779)    GLYCO_HORMONE_ALPHA_2 (PS00780)    GLYCO_HORMONE_ALPHA_3 (PS50277)   
Domaine pattern : Prosite (Expaxy)GLYCO_HORMONE_ALPHA_1 (PS00779)    GLYCO_HORMONE_ALPHA_2 (PS00780)    GLYCO_HORMONE_ALPHA_3 (PS50277)   
Domains : Interpro (SRS)Glyco_hormone   
Domains : Interpro (EBI)Glyco_hormone   
Related proteins : CluSTrP01215
Domain families : Pfam (SRS)Hormone_6 (PF00236)   
Domain families : Pfam (Sanger)Hormone_6 (PF00236)   
Domain families : Pfam (NCBI)pfam00236   
Domain families : Smart (EMBL)GHA (SM00067)  
DMDM1081
Blocks (Seattle)P01215
PDB (SRS)1DZ7    1E9J    1FL7    1HCN    1HD4    1HRP    1QFW    1XUL    1XWD    4AY9   
PDB (PDBSum)1DZ7    1E9J    1FL7    1HCN    1HD4    1HRP    1QFW    1XUL    1XWD    4AY9   
PDB (IMB)1DZ7    1E9J    1FL7    1HCN    1HD4    1HRP    1QFW    1XUL    1XWD    4AY9   
PDB (RSDB)1DZ7    1E9J    1FL7    1HCN    1HD4    1HRP    1QFW    1XUL    1XWD    4AY9   
Human Protein AtlasENSG00000135346
HPRD00342
IPIIPI00000833   
Protein Interaction databases
DIP (DOE-UCLA)P01215
IntAct (EBI)P01215
FunCoupENSG00000135346
REACTOMECGA
Protein Interaction Database1081
BioGRIDCGA
InParanoidP01215
Interologous Interaction database P01215
IntegromeDBCGA
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CGA
SNP (GeneSNP Utah)CGA
SNP : HGBaseCGA
Genetic variants : HAPMAPCGA
Somatic Mutations in Cancer : COSMICCGA 
CONAN: Copy Number AnalysisCGA 
Mutations and Diseases : HGMDCGA
OMIM118850   
GENETests118850   
Disease Genetic AssociationCGA
Huge Navigator CGA [HugePedia]  CGA [HugeCancerGEM]
Genomic VariantsCGA  CGA [DGVbeta]
ClinVarCGA
snp3D : Map Gene to Disease1081
General knowledge
Homologs : HomoloGeneCGA
Homology/Alignments : Family Browser (UCSC)CGA
Phylogenetic Trees/Animal Genes : TreeFamCGA
Chemical/Protein Interactions : CTD1081
Chemical/Pharm GKB GenePA26433
Clinical trialCGA
Cancer Resource (Charite)ENSG00000135346
Ontology : AmiGOhormone activity  protein binding  extracellular region  thyroid hormone generation  signal transduction  cell-cell signaling  positive regulation of cell proliferation  gonad development  peptide hormone processing  positive regulation of cell migration  thyroid gland development  luteinizing hormone secretion  cellular response to hormone stimulus  cellular protein metabolic process  positive regulation of transcription from RNA polymerase II promoter  negative regulation of organ growth  follicle-stimulating hormone secretion  developmental growth  
Ontology : EGO-EBIhormone activity  protein binding  extracellular region  thyroid hormone generation  signal transduction  cell-cell signaling  positive regulation of cell proliferation  gonad development  peptide hormone processing  positive regulation of cell migration  thyroid gland development  luteinizing hormone secretion  cellular response to hormone stimulus  cellular protein metabolic process  positive regulation of transcription from RNA polymerase II promoter  negative regulation of organ growth  follicle-stimulating hormone secretion  developmental growth  
Pathways : KEGGNeuroactive ligand-receptor interactionGnRH signaling pathway
Other databases
Probes
Litterature
PubMed126 Pubmed reference(s) in Entrez
PubGeneCGA
iHOPCGA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:41:28 CEST 2013
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