Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CIAO1 (cytosolic iron-sulfur assembly component 1)

Identity

Alias_namesWDR39
WD repeat domain 39
cytosolic iron-sulfur protein assembly 1 homolog (S. cerevisiae)
cytosolic iron-sulfur protein assembly 1
Alias_symbol (synonym)CIA1
Other alias
HGNC (Hugo) CIAO1
LocusID (NCBI) 9391
Atlas_Id 40082
Location 2q11.2  [Link to chromosome band 2q11]
Location_base_pair Starts at 96266146 and ends at 96274162 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CIAO1 (2q11.2) / CIAO1 (2q11.2)CIAO1 (2q11.2) / CLCN2 (3q27.1)CIAO1 (2q11.2) / DHX34 (19q13.32)
CIAO1 (2q11.2) / TRAPPC9 (8q24.3)CLCN2 (3q27.1) / CIAO1 (2q11.2)GRSF1 (4q13.3) / CIAO1 (2q11.2)
L3MBTL4 (18p11.31) / CIAO1 (2q11.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CIAO1   14280
Cards
Entrez_Gene (NCBI)CIAO1  9391  cytosolic iron-sulfur assembly component 1
AliasesCIA1; WDR39
GeneCards (Weizmann)CIAO1
Ensembl hg19 (Hinxton)ENSG00000144021 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000144021 [Gene_View]  chr2:96266146-96274162 [Contig_View]  CIAO1 [Vega]
ICGC DataPortalENSG00000144021
TCGA cBioPortalCIAO1
AceView (NCBI)CIAO1
Genatlas (Paris)CIAO1
WikiGenes9391
SOURCE (Princeton)CIAO1
Genetics Home Reference (NIH)CIAO1
Genomic and cartography
GoldenPath hg38 (UCSC)CIAO1  -     chr2:96266146-96274162 +  2q11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CIAO1  -     2q11.2   [Description]    (hg19-Feb_2009)
EnsemblCIAO1 - 2q11.2 [CytoView hg19]  CIAO1 - 2q11.2 [CytoView hg38]
Mapping of homologs : NCBICIAO1 [Mapview hg19]  CIAO1 [Mapview hg38]
OMIM604333   
Gene and transcription
Genbank (Entrez)AF086118 AI094333 AK056423 AK092687 AK124703
RefSeq transcript (Entrez)NM_004804
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CIAO1
Cluster EST : UnigeneHs.12109 [ NCBI ]
CGAP (NCI)Hs.12109
Alternative Splicing GalleryENSG00000144021
Gene ExpressionCIAO1 [ NCBI-GEO ]   CIAO1 [ EBI - ARRAY_EXPRESS ]   CIAO1 [ SEEK ]   CIAO1 [ MEM ]
Gene Expression Viewer (FireBrowse)CIAO1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9391
GTEX Portal (Tissue expression)CIAO1
Protein : pattern, domain, 3D structure
UniProt/SwissProtO76071   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO76071  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO76071
Splice isoforms : SwissVarO76071
PhosPhoSitePlusO76071
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)CIAO1/Cia1    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
Conserved Domain (NCBI)CIAO1
DMDM Disease mutations9391
Blocks (Seattle)CIAO1
PDB (SRS)3FM0   
PDB (PDBSum)3FM0   
PDB (IMB)3FM0   
PDB (RSDB)3FM0   
Structural Biology KnowledgeBase3FM0   
SCOP (Structural Classification of Proteins)3FM0   
CATH (Classification of proteins structures)3FM0   
SuperfamilyO76071
Human Protein AtlasENSG00000144021
Peptide AtlasO76071
HPRD16057
IPIIPI00008791   IPI00978990   
Protein Interaction databases
DIP (DOE-UCLA)O76071
IntAct (EBI)O76071
FunCoupENSG00000144021
BioGRIDCIAO1
STRING (EMBL)CIAO1
ZODIACCIAO1
Ontologies - Pathways
QuickGOO76071
Ontology : AmiGOprotein binding  regulation of transcription from RNA polymerase II promoter  chromosome segregation  positive regulation of cell proliferation  iron-sulfur cluster assembly  MMXD complex  CIA complex  
Ontology : EGO-EBIprotein binding  regulation of transcription from RNA polymerase II promoter  chromosome segregation  positive regulation of cell proliferation  iron-sulfur cluster assembly  MMXD complex  CIA complex  
NDEx NetworkCIAO1
Atlas of Cancer Signalling NetworkCIAO1
Wikipedia pathwaysCIAO1
Orthology - Evolution
OrthoDB9391
GeneTree (enSembl)ENSG00000144021
Phylogenetic Trees/Animal Genes : TreeFamCIAO1
HOVERGENO76071
HOGENOMO76071
Homologs : HomoloGeneCIAO1
Homology/Alignments : Family Browser (UCSC)CIAO1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCIAO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CIAO1
dbVarCIAO1
ClinVarCIAO1
1000_GenomesCIAO1 
Exome Variant ServerCIAO1
ExAC (Exome Aggregation Consortium)CIAO1 (select the gene name)
Genetic variants : HAPMAP9391
Genomic Variants (DGV)CIAO1 [DGVbeta]
DECIPHERCIAO1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCIAO1 
Mutations
ICGC Data PortalCIAO1 
TCGA Data PortalCIAO1 
Broad Tumor PortalCIAO1
OASIS PortalCIAO1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCIAO1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCIAO1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CIAO1
DgiDB (Drug Gene Interaction Database)CIAO1
DoCM (Curated mutations)CIAO1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CIAO1 (select a term)
intoGenCIAO1
Cancer3DCIAO1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604333   
Orphanet
MedgenCIAO1
Genetic Testing Registry CIAO1
NextProtO76071 [Medical]
TSGene9391
GENETestsCIAO1
Target ValidationCIAO1
Huge Navigator CIAO1 [HugePedia]
snp3D : Map Gene to Disease9391
BioCentury BCIQCIAO1
ClinGenCIAO1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9391
Chemical/Pharm GKB GenePA162382269
Clinical trialCIAO1
Miscellaneous
canSAR (ICR)CIAO1 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCIAO1
EVEXCIAO1
GoPubMedCIAO1
iHOPCIAO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:28:28 CEST 2017

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