Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CLCA1 (chloride channel accessory 1)

Identity

Alias_nameschloride channel, calcium activated, family member 1
chloride channel regulator 1
Alias_symbol (synonym)CaCC
CLCRG1
Other aliasCACC
CACC1
CaCC-1
GOB5
hCLCA1
hCaCC-1
HGNC (Hugo) CLCA1
LocusID (NCBI) 1179
Atlas_Id 43899
Location 1p22.3  [Link to chromosome band 1p22]
Location_base_pair Starts at 86468843 and ends at 86500291 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLCA1   2015
Cards
Entrez_Gene (NCBI)CLCA1  1179  chloride channel accessory 1
AliasesCACC; CACC1; CLCRG1; CaCC-1; 
GOB5; hCLCA1; hCaCC-1
GeneCards (Weizmann)CLCA1
Ensembl hg19 (Hinxton)ENSG00000016490 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000016490 [Gene_View]  chr1:86468843-86500291 [Contig_View]  CLCA1 [Vega]
ICGC DataPortalENSG00000016490
TCGA cBioPortalCLCA1
AceView (NCBI)CLCA1
Genatlas (Paris)CLCA1
WikiGenes1179
SOURCE (Princeton)CLCA1
Genetics Home Reference (NIH)CLCA1
Genomic and cartography
GoldenPath hg38 (UCSC)CLCA1  -     chr1:86468843-86500291 +  1p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLCA1  -     1p22.3   [Description]    (hg19-Feb_2009)
EnsemblCLCA1 - 1p22.3 [CytoView hg19]  CLCA1 - 1p22.3 [CytoView hg38]
Mapping of homologs : NCBICLCA1 [Mapview hg19]  CLCA1 [Mapview hg38]
OMIM603906   
Gene and transcription
Genbank (Entrez)AA508854 AF039400 AF127036 AK024970 AK097057
RefSeq transcript (Entrez)NM_001285
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLCA1
Cluster EST : UnigeneHs.194659 [ NCBI ]
CGAP (NCI)Hs.194659
Alternative Splicing GalleryENSG00000016490
Gene ExpressionCLCA1 [ NCBI-GEO ]   CLCA1 [ EBI - ARRAY_EXPRESS ]   CLCA1 [ SEEK ]   CLCA1 [ MEM ]
Gene Expression Viewer (FireBrowse)CLCA1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1179
GTEX Portal (Tissue expression)CLCA1
Human Protein AtlasENSG00000016490-CLCA1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA8K7I4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA8K7I4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA8K7I4
Splice isoforms : SwissVarA8K7I4
PhosPhoSitePlusA8K7I4
Domaine pattern : Prosite (Expaxy)VWFA (PS50234)   
Domains : Interpro (EBI)CLCA    CLCA_chordata    VWF_A   
Domain families : Pfam (Sanger)CLCA (PF08434)    VWA_2 (PF13519)   
Domain families : Pfam (NCBI)pfam08434    pfam13519   
Domain families : Smart (EMBL)VWA (SM00327)  
Conserved Domain (NCBI)CLCA1
DMDM Disease mutations1179
Blocks (Seattle)CLCA1
SuperfamilyA8K7I4
Human Protein Atlas [tissue]ENSG00000016490-CLCA1 [tissue]
Peptide AtlasA8K7I4
HPRD04880
IPIIPI00014625   IPI01014324   
Protein Interaction databases
DIP (DOE-UCLA)A8K7I4
IntAct (EBI)A8K7I4
FunCoupENSG00000016490
BioGRIDCLCA1
STRING (EMBL)CLCA1
ZODIACCLCA1
Ontologies - Pathways
QuickGOA8K7I4
Ontology : AmiGOmetalloendopeptidase activity  intracellular calcium activated chloride channel activity  chloride channel activity  extracellular space  plasma membrane  integral component of plasma membrane  microvillus  proteolysis  transport  calcium ion transport  secretory granule  ion transmembrane transport  zymogen granule membrane  metal ion binding  cellular response to hypoxia  chloride transmembrane transport  
Ontology : EGO-EBImetalloendopeptidase activity  intracellular calcium activated chloride channel activity  chloride channel activity  extracellular space  plasma membrane  integral component of plasma membrane  microvillus  proteolysis  transport  calcium ion transport  secretory granule  ion transmembrane transport  zymogen granule membrane  metal ion binding  cellular response to hypoxia  chloride transmembrane transport  
Pathways : KEGGOlfactory transduction    Pancreatic secretion   
NDEx NetworkCLCA1
Atlas of Cancer Signalling NetworkCLCA1
Wikipedia pathwaysCLCA1
Orthology - Evolution
OrthoDB1179
GeneTree (enSembl)ENSG00000016490
Phylogenetic Trees/Animal Genes : TreeFamCLCA1
HOVERGENA8K7I4
HOGENOMA8K7I4
Homologs : HomoloGeneCLCA1
Homology/Alignments : Family Browser (UCSC)CLCA1
Gene fusions - Rearrangements
Tumor Fusion PortalCLCA1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLCA1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLCA1
dbVarCLCA1
ClinVarCLCA1
1000_GenomesCLCA1 
Exome Variant ServerCLCA1
ExAC (Exome Aggregation Consortium)ENSG00000016490
GNOMAD BrowserENSG00000016490
Genetic variants : HAPMAP1179
Genomic Variants (DGV)CLCA1 [DGVbeta]
DECIPHERCLCA1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLCA1 
Mutations
ICGC Data PortalCLCA1 
TCGA Data PortalCLCA1 
Broad Tumor PortalCLCA1
OASIS PortalCLCA1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLCA1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLCA1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLCA1
DgiDB (Drug Gene Interaction Database)CLCA1
DoCM (Curated mutations)CLCA1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLCA1 (select a term)
intoGenCLCA1
Cancer3DCLCA1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603906   
Orphanet
DisGeNETCLCA1
MedgenCLCA1
Genetic Testing Registry CLCA1
NextProtA8K7I4 [Medical]
TSGene1179
GENETestsCLCA1
Target ValidationCLCA1
Huge Navigator CLCA1 [HugePedia]
snp3D : Map Gene to Disease1179
BioCentury BCIQCLCA1
ClinGenCLCA1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1179
Chemical/Pharm GKB GenePA26542
Clinical trialCLCA1
Miscellaneous
canSAR (ICR)CLCA1 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLCA1
EVEXCLCA1
GoPubMedCLCA1
iHOPCLCA1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:07:57 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.