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CLTB (clathrin light chain B)

Identity

Alias_namesclathrin, light polypeptide (Lcb)
clathrin, light chain B
Alias_symbol (synonym)Lcb
Other aliasLCB
HGNC (Hugo) CLTB
LocusID (NCBI) 1212
Atlas_Id 40106
Location 5q35.2  [Link to chromosome band 5q35]
Location_base_pair Starts at 176392455 and ends at 176416569 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLTB (5q35.2) / CLTB (5q35.2)CLTB (5q35.2) / MCMBP (10q26.11)CLTB (5q35.2) / PSMF1 (20p13)
CLTB (5q35.2) / SIL1 (5q31.2)CLTB 5q35.2 / SIL1 5q31.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLTB   2091
Cards
Entrez_Gene (NCBI)CLTB  1212  clathrin light chain B
AliasesLCB
GeneCards (Weizmann)CLTB
Ensembl hg19 (Hinxton)ENSG00000175416 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175416 [Gene_View]  chr5:176392455-176416569 [Contig_View]  CLTB [Vega]
ICGC DataPortalENSG00000175416
TCGA cBioPortalCLTB
AceView (NCBI)CLTB
Genatlas (Paris)CLTB
WikiGenes1212
SOURCE (Princeton)CLTB
Genetics Home Reference (NIH)CLTB
Genomic and cartography
GoldenPath hg38 (UCSC)CLTB  -     chr5:176392455-176416569 -  5q35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLTB  -     5q35.2   [Description]    (hg19-Feb_2009)
EnsemblCLTB - 5q35.2 [CytoView hg19]  CLTB - 5q35.2 [CytoView hg38]
Mapping of homologs : NCBICLTB [Mapview hg19]  CLTB [Mapview hg38]
OMIM118970   
Gene and transcription
Genbank (Entrez)AK300200 BC006332 BC006457 BM761740 BT007028
RefSeq transcript (Entrez)NM_001834 NM_007097
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLTB
Cluster EST : UnigeneHs.484241 [ NCBI ]
CGAP (NCI)Hs.484241
Alternative Splicing GalleryENSG00000175416
Gene ExpressionCLTB [ NCBI-GEO ]   CLTB [ EBI - ARRAY_EXPRESS ]   CLTB [ SEEK ]   CLTB [ MEM ]
Gene Expression Viewer (FireBrowse)CLTB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1212
GTEX Portal (Tissue expression)CLTB
Human Protein AtlasENSG00000175416-CLTB [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09497   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09497  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09497
Splice isoforms : SwissVarP09497
PhosPhoSitePlusP09497
Domaine pattern : Prosite (Expaxy)CLATHRIN_LIGHT_CHN_1 (PS00224)    CLATHRIN_LIGHT_CHN_2 (PS00581)   
Domains : Interpro (EBI)Clathrin_L-chain   
Domain families : Pfam (Sanger)Clathrin_lg_ch (PF01086)   
Domain families : Pfam (NCBI)pfam01086   
Conserved Domain (NCBI)CLTB
DMDM Disease mutations1212
Blocks (Seattle)CLTB
SuperfamilyP09497
Human Protein Atlas [tissue]ENSG00000175416-CLTB [tissue]
Peptide AtlasP09497
HPRD00352
IPIIPI00014589   IPI00216472   IPI00909220   IPI00965502   IPI00965757   
Protein Interaction databases
DIP (DOE-UCLA)P09497
IntAct (EBI)P09497
FunCoupENSG00000175416
BioGRIDCLTB
STRING (EMBL)CLTB
ZODIACCLTB
Ontologies - Pathways
QuickGOP09497
Ontology : AmiGOstructural molecule activity  protein binding  trans-Golgi network  cytosol  cytosol  plasma membrane  intracellular protein transport  clathrin coat  clathrin coat  clathrin vesicle coat  clathrin coat of trans-Golgi network vesicle  clathrin coat of coated pit  clathrin heavy chain binding  peptide binding  intracellular membrane-bounded organelle  ciliary membrane  membrane organization  clathrin-dependent endocytosis  
Ontology : EGO-EBIstructural molecule activity  protein binding  trans-Golgi network  cytosol  cytosol  plasma membrane  intracellular protein transport  clathrin coat  clathrin coat  clathrin vesicle coat  clathrin coat of trans-Golgi network vesicle  clathrin coat of coated pit  clathrin heavy chain binding  peptide binding  intracellular membrane-bounded organelle  ciliary membrane  membrane organization  clathrin-dependent endocytosis  
Pathways : BIOCARTAADP-Ribosylation Factor [Genes]   
Pathways : KEGGLysosome    Endocytosis    Synaptic vesicle cycle    Endocrine and other factor-regulated calcium reabsorption    Huntington's disease    Bacterial invasion of epithelial cells   
NDEx NetworkCLTB
Atlas of Cancer Signalling NetworkCLTB
Wikipedia pathwaysCLTB
Orthology - Evolution
OrthoDB1212
GeneTree (enSembl)ENSG00000175416
Phylogenetic Trees/Animal Genes : TreeFamCLTB
HOVERGENP09497
HOGENOMP09497
Homologs : HomoloGeneCLTB
Homology/Alignments : Family Browser (UCSC)CLTB
Gene fusions - Rearrangements
Fusion : MitelmanCLTB/SIL1 [5q35.2/5q31.2]  
Fusion: TCGA_MDACCCLTB 5q35.2 SIL1 5q31.2 BRCA
Tumor Fusion PortalCLTB
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLTB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLTB
dbVarCLTB
ClinVarCLTB
1000_GenomesCLTB 
Exome Variant ServerCLTB
ExAC (Exome Aggregation Consortium)ENSG00000175416
GNOMAD BrowserENSG00000175416
Genetic variants : HAPMAP1212
Genomic Variants (DGV)CLTB [DGVbeta]
DECIPHERCLTB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLTB 
Mutations
ICGC Data PortalCLTB 
TCGA Data PortalCLTB 
Broad Tumor PortalCLTB
OASIS PortalCLTB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLTB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLTB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLTB
DgiDB (Drug Gene Interaction Database)CLTB
DoCM (Curated mutations)CLTB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLTB (select a term)
intoGenCLTB
Cancer3DCLTB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM118970   
Orphanet
DisGeNETCLTB
MedgenCLTB
Genetic Testing Registry CLTB
NextProtP09497 [Medical]
TSGene1212
GENETestsCLTB
Target ValidationCLTB
Huge Navigator CLTB [HugePedia]
snp3D : Map Gene to Disease1212
BioCentury BCIQCLTB
ClinGenCLTB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1212
Chemical/Pharm GKB GenePA26617
Clinical trialCLTB
Miscellaneous
canSAR (ICR)CLTB (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLTB
EVEXCLTB
GoPubMedCLTB
iHOPCLTB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:08:12 CET 2017

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