Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CNR1 (cannabinoid receptor 1 (brain))

Identity

Alias_namesCNR
cannabinoid receptor 1 (brain)
Alias_symbol (synonym)CB1K5
CB-R
CB1
CANN6
CB1A
HGNC (Hugo) CNR1
LocusID (NCBI) 1268
Atlas_Id 45964
Location 6q15  [Link to chromosome band 6q15]
Location_base_pair Starts at 88849585 and ends at 88875767 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CNR1   2159
Cards
Entrez_Gene (NCBI)CNR1  1268  cannabinoid receptor 1 (brain)
AliasesCANN6; CB-R; CB1; CB1A; 
CB1K5; CB1R; CNR
GeneCards (Weizmann)CNR1
Ensembl hg19 (Hinxton)ENSG00000118432 [Gene_View]  chr6:88849585-88875767 [Contig_View]  CNR1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000118432 [Gene_View]  chr6:88849585-88875767 [Contig_View]  CNR1 [Vega]
ICGC DataPortalENSG00000118432
TCGA cBioPortalCNR1
AceView (NCBI)CNR1
Genatlas (Paris)CNR1
WikiGenes1268
SOURCE (Princeton)CNR1
Genetics Home Reference (NIH)CNR1
Genomic and cartography
GoldenPath hg19 (UCSC)CNR1  -     chr6:88849585-88875767 -  6q15   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CNR1  -     6q15   [Description]    (hg38-Dec_2013)
EnsemblCNR1 - 6q15 [CytoView hg19]  CNR1 - 6q15 [CytoView hg38]
Mapping of homologs : NCBICNR1 [Mapview hg19]  CNR1 [Mapview hg38]
OMIM114610   
Gene and transcription
Genbank (Entrez)AF107262 AK313908 AY766182 AY995204 BC074811
RefSeq transcript (Entrez)NM_001160226 NM_001160258 NM_001160259 NM_001160260 NM_016083 NM_033181
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_025741 NW_004929327
Consensus coding sequences : CCDS (NCBI)CNR1
Cluster EST : UnigeneHs.75110 [ NCBI ]
CGAP (NCI)Hs.75110
Alternative Splicing GalleryENSG00000118432
Gene ExpressionCNR1 [ NCBI-GEO ]   CNR1 [ EBI - ARRAY_EXPRESS ]   CNR1 [ SEEK ]   CNR1 [ MEM ]
Gene Expression Viewer (FireBrowse)CNR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1268
GTEX Portal (Tissue expression)CNR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP21554   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP21554  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP21554
Splice isoforms : SwissVarP21554
PhosPhoSitePlusP21554
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)Canbinoid_rcpt_1    Cnbnoid_rcpt    GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)CNR1
DMDM Disease mutations1268
Blocks (Seattle)CNR1
PDB (SRS)1LVQ    1LVR    2B0Y    2KOE   
PDB (PDBSum)1LVQ    1LVR    2B0Y    2KOE   
PDB (IMB)1LVQ    1LVR    2B0Y    2KOE   
PDB (RSDB)1LVQ    1LVR    2B0Y    2KOE   
Structural Biology KnowledgeBase1LVQ    1LVR    2B0Y    2KOE   
SCOP (Structural Classification of Proteins)1LVQ    1LVR    2B0Y    2KOE   
CATH (Classification of proteins structures)1LVQ    1LVR    2B0Y    2KOE   
SuperfamilyP21554
Human Protein AtlasENSG00000118432
Peptide AtlasP21554
HPRD00259
IPIIPI00009396   IPI00215993   IPI00655874   IPI01018356   IPI00985031   
Protein Interaction databases
DIP (DOE-UCLA)P21554
IntAct (EBI)P21554
FunCoupENSG00000118432
BioGRIDCNR1
STRING (EMBL)CNR1
ZODIACCNR1
Ontologies - Pathways
QuickGOP21554
Ontology : AmiGOpositive regulation of acute inflammatory response to antigenic stimulus  cannabinoid receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  spermatogenesis  axonal fasciculation  aging  response to nutrient  memory  drug binding  positive regulation of neuron projection development  sensory perception of pain  axon  growth cone  positive regulation of fever generation  negative regulation of fatty acid beta-oxidation  regulation of synaptic transmission, GABAergic  response to lipopolysaccharide  negative regulation of mast cell activation  negative regulation of dopamine secretion  response to nicotine  cannabinoid signaling pathway  response to cocaine  glucose homeostasis  positive regulation of apoptotic process  intracellular membrane-bounded organelle  response to morphine  membrane raft  response to ethanol  negative regulation of action potential  negative regulation of blood pressure  positive regulation of blood pressure  regulation of insulin secretion  negative regulation of nitric-oxide synthase activity  regulation of synaptic transmission, glutamatergic  maternal process involved in female pregnancy  regulation of feeding behavior  regulation of penile erection  
Ontology : EGO-EBIpositive regulation of acute inflammatory response to antigenic stimulus  cannabinoid receptor activity  plasma membrane  integral component of plasma membrane  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  spermatogenesis  axonal fasciculation  aging  response to nutrient  memory  drug binding  positive regulation of neuron projection development  sensory perception of pain  axon  growth cone  positive regulation of fever generation  negative regulation of fatty acid beta-oxidation  regulation of synaptic transmission, GABAergic  response to lipopolysaccharide  negative regulation of mast cell activation  negative regulation of dopamine secretion  response to nicotine  cannabinoid signaling pathway  response to cocaine  glucose homeostasis  positive regulation of apoptotic process  intracellular membrane-bounded organelle  response to morphine  membrane raft  response to ethanol  negative regulation of action potential  negative regulation of blood pressure  positive regulation of blood pressure  regulation of insulin secretion  negative regulation of nitric-oxide synthase activity  regulation of synaptic transmission, glutamatergic  maternal process involved in female pregnancy  regulation of feeding behavior  regulation of penile erection  
Pathways : BIOCARTAMetabolism of Anandamide, an Endogenous Cannabinoid [Genes]   
Pathways : KEGGRap1 signaling pathway    Neuroactive ligand-receptor interaction    Retrograde endocannabinoid signaling   
NDEx NetworkCNR1
Atlas of Cancer Signalling NetworkCNR1
Wikipedia pathwaysCNR1
Orthology - Evolution
OrthoDB1268
GeneTree (enSembl)ENSG00000118432
Phylogenetic Trees/Animal Genes : TreeFamCNR1
HOVERGENP21554
HOGENOMP21554
Homologs : HomoloGeneCNR1
Homology/Alignments : Family Browser (UCSC)CNR1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCNR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CNR1
dbVarCNR1
ClinVarCNR1
1000_GenomesCNR1 
Exome Variant ServerCNR1
ExAC (Exome Aggregation Consortium)CNR1 (select the gene name)
Genetic variants : HAPMAP1268
Genomic Variants (DGV)CNR1 [DGVbeta]
DECIPHER (Syndromes)6:88849585-88875767  ENSG00000118432
CONAN: Copy Number AnalysisCNR1 
Mutations
ICGC Data PortalCNR1 
TCGA Data PortalCNR1 
Broad Tumor PortalCNR1
OASIS PortalCNR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCNR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCNR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CNR1
DgiDB (Drug Gene Interaction Database)CNR1
DoCM (Curated mutations)CNR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CNR1 (select a term)
intoGenCNR1
Cancer3DCNR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM114610   
Orphanet
MedgenCNR1
Genetic Testing Registry CNR1
NextProtP21554 [Medical]
TSGene1268
GENETestsCNR1
Huge Navigator CNR1 [HugePedia]
snp3D : Map Gene to Disease1268
BioCentury BCIQCNR1
ClinGenCNR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1268
Chemical/Pharm GKB GenePA26681
Clinical trialCNR1
Miscellaneous
canSAR (ICR)CNR1 (select the gene name)
Probes
Litterature
PubMed378 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCNR1
EVEXCNR1
GoPubMedCNR1
iHOPCNR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Nov 18 19:34:21 CET 2016

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