Atlas of Genetics and Cytogenetics in Oncology and Haematology


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COX10 (cytochrome c oxidase assembly homolog 10 (yeast))

Identity

Other names-
HGNC (Hugo) COX10
LocusID (NCBI) 1352
Location 17p12
Location_base_pair Starts at 13972719 and ends at 14111996 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)COX10   2260
Cards
Entrez_Gene (NCBI)COX10  1352  cytochrome c oxidase assembly homolog 10 (yeast)
GeneCards (Weizmann)COX10
Ensembl (Hinxton)ENSG00000006695 [Gene_View]  chr17:13972719-14111996 [Contig_View]  COX10 [Vega]
ICGC DataPortalENSG00000006695
cBioPortalCOX10
AceView (NCBI)COX10
Genatlas (Paris)COX10
WikiGenes1352
SOURCE (Princeton)NM_001303
Genomic and cartography
GoldenPath (UCSC)COX10  -  17p12   chr17:13972719-14111996 +  17p12   [Description]    (hg19-Feb_2009)
EnsemblCOX10 - 17p12 [CytoView]
Mapping of homologs : NCBICOX10 [Mapview]
OMIM220110   602125   
Gene and transcription
Genbank (Entrez)AK294213 AK295925 AK312718 BC000060 BC006394
RefSeq transcript (Entrez)NM_001303
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_008034 NT_010718 NW_001838403 NW_004929405
Consensus coding sequences : CCDS (NCBI)COX10
Cluster EST : UnigeneHs.462278 [ NCBI ]
CGAP (NCI)Hs.462278
Alternative Splicing : Fast-db (Paris)GSHG0012241
Alternative Splicing GalleryENSG00000006695
Gene ExpressionCOX10 [ NCBI-GEO ]     COX10 [ SEEK ]   COX10 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ12887 (Uniprot)
NextProtQ12887  [Medical]
With graphics : InterProQ12887
Splice isoforms : SwissVarQ12887 (Swissvar)
Catalytic activity : Enzyme2.5.1.- [ Enzyme-Expasy ]   2.5.1.-2.5.1.- [ IntEnz-EBI ]   2.5.1.- [ BRENDA ]   2.5.1.- [ KEGG ]   
Domaine pattern : Prosite (Expaxy)UBIA (PS00943)   
Domains : Interpro (EBI)Protohaem_IX_farnesylTrfase [organisation]   Protohaem_IX_farnesylTrfase_mt [organisation]   UbiA_prenyltransferase [organisation]  
Related proteins : CluSTrQ12887
Domain families : Pfam (Sanger)UbiA (PF01040)   
Domain families : Pfam (NCBI)pfam01040   
DMDM Disease mutations1352
Blocks (Seattle)Q12887
Human Protein AtlasENSG00000006695 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ12887
HPRD03673
IPIIPI00290099   IPI01009495   IPI01010758   IPI00795355   
Protein Interaction databases
DIP (DOE-UCLA)Q12887
IntAct (EBI)Q12887
FunCoupENSG00000006695
BioGRIDCOX10
InParanoidQ12887
Interologous Interaction database Q12887
IntegromeDBCOX10
STRING (EMBL)COX10
Ontologies - Pathways
Ontology : AmiGOmitochondrial fission  cytochrome-c oxidase activity  farnesyltranstransferase activity  mitochondrion  mitochondrial inner membrane  mitochondrial electron transport, cytochrome c to oxygen  porphyrin-containing compound metabolic process  heme biosynthetic process  heme a biosynthetic process  protoheme IX farnesyltransferase activity  respiratory chain complex IV assembly  aerobic respiration  integral component of membrane  small molecule metabolic process  cellular respiration  heme O biosynthetic process  hydrogen ion transmembrane transport  
Ontology : EGO-EBImitochondrial fission  cytochrome-c oxidase activity  farnesyltranstransferase activity  mitochondrion  mitochondrial inner membrane  mitochondrial electron transport, cytochrome c to oxygen  porphyrin-containing compound metabolic process  heme biosynthetic process  heme a biosynthetic process  protoheme IX farnesyltransferase activity  respiratory chain complex IV assembly  aerobic respiration  integral component of membrane  small molecule metabolic process  cellular respiration  heme O biosynthetic process  hydrogen ion transmembrane transport  
Pathways : KEGGOxidative phosphorylation    Porphyrin and chlorophyll metabolism   
Protein Interaction DatabaseCOX10
Wikipedia pathwaysCOX10
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)COX10
snp3D : Map Gene to Disease1352
SNP (GeneSNP Utah)COX10
SNP : HGBaseCOX10
Genetic variants : HAPMAPCOX10
Exome VariantCOX10
1000_GenomesCOX10 
ICGC programENSG00000006695 
Somatic Mutations in Cancer : COSMICCOX10 
CONAN: Copy Number AnalysisCOX10 
Mutations and Diseases : HGMDCOX10
Genomic VariantsCOX10  COX10 [DGVbeta]
dbVarCOX10
ClinVarCOX10
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM220110    602125   
MedgenCOX10
GENETestsCOX10
Disease Genetic AssociationCOX10
Huge Navigator COX10 [HugePedia]  COX10 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCOX10
Homology/Alignments : Family Browser (UCSC)COX10
Phylogenetic Trees/Animal Genes : TreeFamCOX10
Chemical/Protein Interactions : CTD1352
Chemical/Pharm GKB GenePA26776
Clinical trialCOX10
Cancer Resource (Charite)ENSG00000006695
Other databases
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
CoreMineCOX10
iHOPCOX10
OncoSearchCOX10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jul 30 13:49:17 CEST 2014

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