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CRTAM (cytotoxic and regulatory T cell molecule)

Identity

Alias_namescytotoxic and regulatory T cell molecule
Alias_symbol (synonym)CD355
Other alias
HGNC (Hugo) CRTAM
LocusID (NCBI) 56253
Atlas_Id 45934
Location 11q24.1  [Link to chromosome band 11q24]
Location_base_pair Starts at 122838498 and ends at 122872639 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CRTAM (11q24.1) / ACTG1 (17q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CRTAM   24313
Cards
Entrez_Gene (NCBI)CRTAM  56253  cytotoxic and regulatory T cell molecule
AliasesCD355
GeneCards (Weizmann)CRTAM
Ensembl hg19 (Hinxton)ENSG00000109943 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109943 [Gene_View]  ENSG00000109943 [Sequence]  chr11:122838498-122872639 [Contig_View]  CRTAM [Vega]
ICGC DataPortalENSG00000109943
TCGA cBioPortalCRTAM
AceView (NCBI)CRTAM
Genatlas (Paris)CRTAM
WikiGenes56253
SOURCE (Princeton)CRTAM
Genetics Home Reference (NIH)CRTAM
Genomic and cartography
GoldenPath hg38 (UCSC)CRTAM  -     chr11:122838498-122872639 +  11q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CRTAM  -     11q24.1   [Description]    (hg19-Feb_2009)
EnsemblCRTAM - 11q24.1 [CytoView hg19]  CRTAM - 11q24.1 [CytoView hg38]
Mapping of homologs : NCBICRTAM [Mapview hg19]  CRTAM [Mapview hg38]
OMIM612597   
Gene and transcription
Genbank (Entrez)AB209830 AF001622 AK293470 AK313578 BC070266
RefSeq transcript (Entrez)NM_001304782 NM_019604
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CRTAM
Cluster EST : UnigeneHs.159523 [ NCBI ]
CGAP (NCI)Hs.159523
Alternative Splicing GalleryENSG00000109943
Gene ExpressionCRTAM [ NCBI-GEO ]   CRTAM [ EBI - ARRAY_EXPRESS ]   CRTAM [ SEEK ]   CRTAM [ MEM ]
Gene Expression Viewer (FireBrowse)CRTAM [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56253
GTEX Portal (Tissue expression)CRTAM
Human Protein AtlasENSG00000109943-CRTAM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95727   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95727  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95727
Splice isoforms : SwissVarO95727
PhosPhoSitePlusO95727
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)CD80_C2-set    Ig-like_dom    Ig-like_fold    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)C2-set_2 (PF08205)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam08205    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)CRTAM
DMDM Disease mutations56253
Blocks (Seattle)CRTAM
PDB (SRS)3RBG    4H5S   
PDB (PDBSum)3RBG    4H5S   
PDB (IMB)3RBG    4H5S   
PDB (RSDB)3RBG    4H5S   
Structural Biology KnowledgeBase3RBG    4H5S   
SCOP (Structural Classification of Proteins)3RBG    4H5S   
CATH (Classification of proteins structures)3RBG    4H5S   
SuperfamilyO95727
Human Protein Atlas [tissue]ENSG00000109943-CRTAM [tissue]
Peptide AtlasO95727
HPRD16760
IPIIPI00159048   IPI00847808   
Protein Interaction databases
DIP (DOE-UCLA)O95727
IntAct (EBI)O95727
FunCoupENSG00000109943
BioGRIDCRTAM
STRING (EMBL)CRTAM
ZODIACCRTAM
Ontologies - Pathways
QuickGOO95727
Ontology : AmiGOT cell mediated cytotoxicity  detection of tumor cell  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  receptor activity  receptor binding  plasma membrane  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  protein homodimerization activity  positive regulation of natural killer cell mediated cytotoxicity  positive regulation of cytokine secretion  regulation of immune response  activated T cell proliferation  cell adhesion molecule binding  detection of stimulus  
Ontology : EGO-EBIT cell mediated cytotoxicity  detection of tumor cell  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  receptor activity  receptor binding  plasma membrane  plasma membrane  integral component of plasma membrane  cell-cell adherens junction  homophilic cell adhesion via plasma membrane adhesion molecules  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  protein homodimerization activity  positive regulation of natural killer cell mediated cytotoxicity  positive regulation of cytokine secretion  regulation of immune response  activated T cell proliferation  cell adhesion molecule binding  detection of stimulus  
NDEx NetworkCRTAM
Atlas of Cancer Signalling NetworkCRTAM
Wikipedia pathwaysCRTAM
Orthology - Evolution
OrthoDB56253
GeneTree (enSembl)ENSG00000109943
Phylogenetic Trees/Animal Genes : TreeFamCRTAM
HOVERGENO95727
HOGENOMO95727
Homologs : HomoloGeneCRTAM
Homology/Alignments : Family Browser (UCSC)CRTAM
Gene fusions - Rearrangements
Fusion : QuiverCRTAM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCRTAM [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CRTAM
dbVarCRTAM
ClinVarCRTAM
1000_GenomesCRTAM 
Exome Variant ServerCRTAM
ExAC (Exome Aggregation Consortium)ENSG00000109943
GNOMAD BrowserENSG00000109943
Genetic variants : HAPMAP56253
Genomic Variants (DGV)CRTAM [DGVbeta]
DECIPHERCRTAM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCRTAM 
Mutations
ICGC Data PortalCRTAM 
TCGA Data PortalCRTAM 
Broad Tumor PortalCRTAM
OASIS PortalCRTAM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCRTAM  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCRTAM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CRTAM
DgiDB (Drug Gene Interaction Database)CRTAM
DoCM (Curated mutations)CRTAM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CRTAM (select a term)
intoGenCRTAM
Cancer3DCRTAM(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612597   
Orphanet
DisGeNETCRTAM
MedgenCRTAM
Genetic Testing Registry CRTAM
NextProtO95727 [Medical]
TSGene56253
GENETestsCRTAM
Target ValidationCRTAM
Huge Navigator CRTAM [HugePedia]
snp3D : Map Gene to Disease56253
BioCentury BCIQCRTAM
ClinGenCRTAM
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56253
Chemical/Pharm GKB GenePA145149072
Clinical trialCRTAM
Miscellaneous
canSAR (ICR)CRTAM (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCRTAM
EVEXCRTAM
GoPubMedCRTAM
iHOPCRTAM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri Jun 22 16:20:58 CEST 2018
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