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CRTAM (cytotoxic and regulatory T cell molecule)

Identity

Alias (NCBI)CD355
HGNC (Hugo) CRTAM
HGNC Alias symbCD355
HGNC Alias nameclass I MHC restricted T cell associated molecule
LocusID (NCBI) 56253
Atlas_Id 45934
Location 11q24.1  [Link to chromosome band 11q24]
Location_base_pair Starts at 122838500 and ends at 122872643 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CRTAM (11q24.1) / ACTG1 (17q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CRTAM   24313
Cards
Entrez_Gene (NCBI)CRTAM    cytotoxic and regulatory T cell molecule
AliasesCD355
GeneCards (Weizmann)CRTAM
Ensembl hg19 (Hinxton)ENSG00000109943 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109943 [Gene_View]  ENSG00000109943 [Sequence]  chr11:122838500-122872643 [Contig_View]  CRTAM [Vega]
ICGC DataPortalENSG00000109943
TCGA cBioPortalCRTAM
AceView (NCBI)CRTAM
Genatlas (Paris)CRTAM
SOURCE (Princeton)CRTAM
Genetics Home Reference (NIH)CRTAM
Genomic and cartography
GoldenPath hg38 (UCSC)CRTAM  -     chr11:122838500-122872643 +  11q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CRTAM  -     11q24.1   [Description]    (hg19-Feb_2009)
GoldenPathCRTAM - 11q24.1 [CytoView hg19]  CRTAM - 11q24.1 [CytoView hg38]
ImmunoBaseENSG00000109943
genome Data Viewer NCBICRTAM [Mapview hg19]  
OMIM612597   
Gene and transcription
Genbank (Entrez)AB209830 AF001622 AK293470 AK313578 BC070266
RefSeq transcript (Entrez)NM_001304782 NM_019604
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CRTAM
Alternative Splicing GalleryENSG00000109943
Gene ExpressionCRTAM [ NCBI-GEO ]   CRTAM [ EBI - ARRAY_EXPRESS ]   CRTAM [ SEEK ]   CRTAM [ MEM ]
Gene Expression Viewer (FireBrowse)CRTAM [ Firebrowse - Broad ]
GenevisibleExpression of CRTAM in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56253
GTEX Portal (Tissue expression)CRTAM
Human Protein AtlasENSG00000109943-CRTAM [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95727   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95727  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95727
Splice isoforms : SwissVarO95727
PhosPhoSitePlusO95727
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)CD80_C2-set    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)C2-set_2 (PF08205)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam08205    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)CRTAM
Blocks (Seattle)CRTAM
PDB (RSDB)3RBG    4H5S   
PDB Europe3RBG    4H5S   
PDB (PDBSum)3RBG    4H5S   
PDB (IMB)3RBG    4H5S   
Structural Biology KnowledgeBase3RBG    4H5S   
SCOP (Structural Classification of Proteins)3RBG    4H5S   
CATH (Classification of proteins structures)3RBG    4H5S   
SuperfamilyO95727
Human Protein Atlas [tissue]ENSG00000109943-CRTAM [tissue]
Peptide AtlasO95727
HPRD16760
IPIIPI00159048   IPI00847808   
Protein Interaction databases
DIP (DOE-UCLA)O95727
IntAct (EBI)O95727
BioGRIDCRTAM
STRING (EMBL)CRTAM
ZODIACCRTAM
Ontologies - Pathways
QuickGOO95727
Ontology : AmiGOestablishment of T cell polarity  immunological synapse  T cell mediated cytotoxicity  detection of tumor cell  detection of tumor cell  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  signaling receptor binding  signaling receptor binding  plasma membrane  plasma membrane  plasma membrane  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  cell recognition  integral component of membrane  positive regulation of interferon-gamma production  regulation of T cell differentiation  positive regulation of natural killer cell mediated cytotoxicity  negative regulation of activated T cell proliferation  positive regulation of cytokine secretion  regulation of immune response  activated T cell proliferation  regulation of T cell activation  detection of stimulus  lymphocyte migration into lymphoid organs  regulation of CD8-positive, alpha-beta T cell activation  
Ontology : EGO-EBIestablishment of T cell polarity  immunological synapse  T cell mediated cytotoxicity  detection of tumor cell  detection of tumor cell  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target  signaling receptor binding  signaling receptor binding  plasma membrane  plasma membrane  plasma membrane  heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules  cell recognition  cell recognition  integral component of membrane  positive regulation of interferon-gamma production  regulation of T cell differentiation  positive regulation of natural killer cell mediated cytotoxicity  negative regulation of activated T cell proliferation  positive regulation of cytokine secretion  regulation of immune response  activated T cell proliferation  regulation of T cell activation  detection of stimulus  lymphocyte migration into lymphoid organs  regulation of CD8-positive, alpha-beta T cell activation  
NDEx NetworkCRTAM
Atlas of Cancer Signalling NetworkCRTAM
Wikipedia pathwaysCRTAM
Orthology - Evolution
OrthoDB56253
GeneTree (enSembl)ENSG00000109943
Phylogenetic Trees/Animal Genes : TreeFamCRTAM
HOGENOMO95727
Homologs : HomoloGeneCRTAM
Homology/Alignments : Family Browser (UCSC)CRTAM
Gene fusions - Rearrangements
Fusion : QuiverCRTAM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCRTAM [hg38]
dbVarCRTAM
ClinVarCRTAM
MonarchCRTAM
1000_GenomesCRTAM 
Exome Variant ServerCRTAM
GNOMAD BrowserENSG00000109943
Varsome BrowserCRTAM
Genomic Variants (DGV)CRTAM [DGVbeta]
DECIPHERCRTAM [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCRTAM 
Mutations
ICGC Data PortalCRTAM 
TCGA Data PortalCRTAM 
Broad Tumor PortalCRTAM
OASIS PortalCRTAM [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCRTAM  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCRTAM
Mutations and Diseases : HGMDCRTAM
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CRTAM
DgiDB (Drug Gene Interaction Database)CRTAM
DoCM (Curated mutations)CRTAM (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CRTAM (select a term)
intoGenCRTAM
Cancer3DCRTAM(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612597   
Orphanet
DisGeNETCRTAM
MedgenCRTAM
Genetic Testing Registry CRTAM
NextProtO95727 [Medical]
GENETestsCRTAM
Target ValidationCRTAM
Huge Navigator CRTAM [HugePedia]
ClinGenCRTAM
Clinical trials, drugs, therapy
MyCancerGenomeCRTAM
Protein Interactions : CTD
Pharm GKB GenePA145149072
PharosO95727
Clinical trialCRTAM
Miscellaneous
canSAR (ICR)CRTAM (select the gene name)
HarmonizomeCRTAM
DataMed IndexCRTAM
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCRTAM
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri Jan 1 18:11:27 CET 2021
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