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CST3 (cystatin C)

Identity

Other namesARMD11
HGNC (Hugo) CST3
LocusID (NCBI) 1471
Location 20p11.21
Location_base_pair Starts at 23614294 and ends at 23618685 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CST3   2475
Cards
Entrez_Gene (NCBI)CST3  1471  cystatin C
GeneCards (Weizmann)CST3
Ensembl (Hinxton)ENSG00000101439 [Gene_View]  chr20:23614294-23618685 [Contig_View]  CST3 [Vega]
ICGC DataPortalENSG00000101439
AceView (NCBI)CST3
Genatlas (Paris)CST3
WikiGenes1471
SOURCE (Princeton)NM_000099 NM_001288614
Genomic and cartography
GoldenPath (UCSC)CST3  -  20p11.21   chr20:23614294-23618685 -  20p11.21   [Description]    (hg19-Feb_2009)
EnsemblCST3 - 20p11.21 [CytoView]
Mapping of homologs : NCBICST3 [Mapview]
OMIM105150   604312   611953   
Gene and transcription
Genbank (Entrez)AB587083 AK312213 BC013083 BC110305 BF509512
RefSeq transcript (Entrez)NM_000099 NM_001288614
RefSeq genomic (Entrez)AC_000152 NC_000020 NC_018931 NG_012887 NT_011387 NW_001838653 NW_004929416
Consensus coding sequences : CCDS (NCBI)CST3
Cluster EST : UnigeneHs.304682 [ NCBI ]
CGAP (NCI)Hs.304682
Alternative Splicing : Fast-db (Paris)GSHG0019070
Alternative Splicing GalleryENSG00000101439
Gene ExpressionCST3 [ NCBI-GEO ]     CST3 [ SEEK ]   CST3 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01034 (Uniprot)
NextProtP01034  [Medical]
With graphics : InterProP01034
Splice isoforms : SwissVarP01034 (Swissvar)
Domaine pattern : Prosite (Expaxy)CYSTATIN (PS00287)   
Domains : Interpro (EBI)Cystatin    Prot_inh_cystat    Prot_inh_cystat_CS   
Related proteins : CluSTrP01034
Domain families : Pfam (Sanger)Cystatin (PF00031)   
Domain families : Pfam (NCBI)pfam00031   
Domain families : Smart (EMBL)CY (SM00043)  
DMDM Disease mutations1471
Blocks (Seattle)P01034
PDB (SRS)1G96    1R4C    1TIJ    3GAX    3NX0    3PS8    3QRD    3S67    3SVA   
PDB (PDBSum)1G96    1R4C    1TIJ    3GAX    3NX0    3PS8    3QRD    3S67    3SVA   
PDB (IMB)1G96    1R4C    1TIJ    3GAX    3NX0    3PS8    3QRD    3S67    3SVA   
PDB (RSDB)1G96    1R4C    1TIJ    3GAX    3NX0    3PS8    3QRD    3S67    3SVA   
Human Protein AtlasENSG00000101439
Peptide AtlasP01034
HPRD05056
IPIIPI00032293   
Protein Interaction databases
DIP (DOE-UCLA)P01034
IntAct (EBI)P01034
FunCoupENSG00000101439
BioGRIDCST3
IntegromeDBCST3
STRING (EMBL)CST3
Ontologies - Pathways
QuickGOP01034
Ontology : AmiGObeta-amyloid binding  protease binding  endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  protein binding  extracellular region  extracellular region  extracellular space  defense response  negative regulation of peptidase activity  negative regulation of collagen catabolic process  negative regulation of extracellular matrix disassembly  negative regulation of extracellular matrix disassembly  negative regulation of endopeptidase activity  negative regulation of endopeptidase activity  regulation of tissue remodeling  extracellular fibril organization  negative regulation of proteolysis  negative regulation of elastin catabolic process  negative regulation of blood vessel remodeling  extracellular vesicular exosome  
Ontology : EGO-EBIbeta-amyloid binding  protease binding  endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  protein binding  extracellular region  extracellular region  extracellular space  defense response  negative regulation of peptidase activity  negative regulation of collagen catabolic process  negative regulation of extracellular matrix disassembly  negative regulation of extracellular matrix disassembly  negative regulation of endopeptidase activity  negative regulation of endopeptidase activity  regulation of tissue remodeling  extracellular fibril organization  negative regulation of proteolysis  negative regulation of elastin catabolic process  negative regulation of blood vessel remodeling  extracellular vesicular exosome  
Pathways : KEGGSalivary secretion   
Protein Interaction DatabaseCST3
Wikipedia pathwaysCST3
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CST3
SNP (GeneSNP Utah)CST3
SNP : HGBaseCST3
Genetic variants : HAPMAPCST3
1000_GenomesCST3 
ICGC programENSG00000101439 
CONAN: Copy Number AnalysisCST3 
Somatic Mutations in Cancer : COSMICCST3 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)20:23614294-23618685
Mutations and Diseases : HGMDCST3
OMIM105150    604312    611953   
MedgenCST3
GENETestsCST3
Disease Genetic AssociationCST3
Huge Navigator CST3 [HugePedia]  CST3 [HugeCancerGEM]
Genomic VariantsCST3  CST3 [DGVbeta]
Exome VariantCST3
dbVarCST3
ClinVarCST3
snp3D : Map Gene to Disease1471
General knowledge
Homologs : HomoloGeneCST3
Homology/Alignments : Family Browser (UCSC)CST3
Phylogenetic Trees/Animal Genes : TreeFamCST3
Chemical/Protein Interactions : CTD1471
Chemical/Pharm GKB GenePA26976
Clinical trialCST3
Cancer Resource (Charite)ENSG00000101439
Other databases
Probes
Litterature
PubMed337 Pubmed reference(s) in Entrez
CoreMineCST3
GoPubMedCST3
iHOPCST3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:20:19 CET 2014

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