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CST3 (cystatin C)

Identity

Other namesARMD11
HGNC (Hugo) CST3
LocusID (NCBI) 1471
Location 20p11.21
Location_base_pair Starts at 23614294 and ends at 23618574 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CST3   2475
Entrez_Gene (NCBI)CST3  1471  cystatin C
Cards
GeneCards (Weizmann)CST3
Ensembl (Hinxton)ENSG00000101439 [Gene_View]  chr20:23614294-23618574 [Contig_View]  CST3 [Vega]
AceView (NCBI)CST3
Genatlas (Paris)CST3
SOURCE (Stanford)NM_000099
Genomic and cartography
GoldenPath (UCSC)CST3  -  20p11.21   chr20:23614294-23618574 -  20p11.21   [Description]    (hg19-Feb_2009)
EnsemblCST3 - 20p11.21 [CytoView]
Mapping of homologs : NCBICST3 [Mapview]
OMIM105150   604312   611953   
Gene and transcription
Genbank (Entrez)AB587083 AK312213 BC013083 BC110305 BT006839
RefSeq transcript (SRS)NM_000099
RefSeq transcript (Entrez)NM_000099
RefSeq genomic (SRS)AC_000152 NC_000020 NC_018931 NG_012887 NT_011387 NW_001838653 NW_004078100
RefSeq genomic (Entrez)AC_000152 NC_000020 NC_018931 NG_012887 NT_011387 NW_001838653 NW_004078100
Consensus coding sequences : CCDS (NCBI)CST3
Cluster EST : UnigeneHs.304682 [ SRS ] Hs.304682 [ NCBI ]
CGAP (NCI)Hs.304682
Alternative Splicing : Fast-db (Paris)GSHG0019070
Alternative Splicing GalleryENSG00000101439
Gene ExpressionCST3 [ NCBI-GEO ]   CST3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP01034 (SRS) P01034 (Uniprot)
NextProtP01034
With graphics : InterProP01034
Splice isoforms : SwissVarP01034(Swissvar)
Domaine pattern : Prosite (SRS)CYSTATIN (PS00287)   
Domaine pattern : Prosite (Expaxy)CYSTATIN (PS00287)   
Domains : Interpro (SRS)Prot_inh_cystat    Prot_inh_cystat_CS   
Domains : Interpro (EBI)Prot_inh_cystat    Prot_inh_cystat_CS   
Related proteins : CluSTrP01034
Domain families : Pfam (SRS)Cystatin (PF00031)   
Domain families : Pfam (Sanger)Cystatin (PF00031)   
Domain families : Pfam (NCBI)pfam00031   
Domain families : Smart (EMBL)CY (SM00043)  
DMDM1471
Blocks (Seattle)P01034
PDB (SRS)1G96    1R4C    1TIJ    3GAX    3NX0    3PS8    3QRD    3S67    3SVA   
PDB (PDBSum)1G96    1R4C    1TIJ    3GAX    3NX0    3PS8    3QRD    3S67    3SVA   
PDB (IMB)1G96    1R4C    1TIJ    3GAX    3NX0    3PS8    3QRD    3S67    3SVA   
PDB (RSDB)1G96    1R4C    1TIJ    3GAX    3NX0    3PS8    3QRD    3S67    3SVA   
Human Protein AtlasENSG00000101439
HPRD05056
IPIIPI00032293   
Protein Interaction databases
DIP (DOE-UCLA)P01034
IntAct (EBI)P01034
FunCoupENSG00000101439
REACTOMECST3
Protein Interaction Database1471
BioGRIDCST3
InParanoidP01034
Interologous Interaction database P01034
IntegromeDBCST3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CST3
SNP (GeneSNP Utah)CST3
SNP : HGBaseCST3
Genetic variants : HAPMAPCST3
Somatic Mutations in Cancer : COSMICCST3 
CONAN: Copy Number AnalysisCST3 
Mutations and Diseases : HGMDCST3
OMIM105150    604312    611953   
GENETests105150    604312    611953   
Disease Genetic AssociationCST3
Huge Navigator CST3 [HugePedia]  CST3 [HugeCancerGEM]
Genomic VariantsCST3  CST3 [DGVbeta]
snp3D : Map Gene to Disease1471
General knowledge
Homologs : HomoloGeneCST3
Homology/Alignments : Family Browser (UCSC)CST3
Phylogenetic Trees/Animal Genes : TreeFamCST3
Chemical/Protein Interactions : CTD1471
Chemical/Pharm GKB GenePA26976
Clinical trialCST3
Cancer Resource (Charite)ENSG00000101439
Ontology : AmiGObeta-amyloid binding  eye development  response to hypoxia  cell activation  protease binding  endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  protein binding  extracellular region  extracellular region  basement membrane  extracellular space  lysosome  multivesicular body  endoplasmic reticulum  apoptotic process  defense response  brain development  salivary gland development  embryo implantation  positive regulation of cell proliferation  response to toxin  response to carbohydrate stimulus  response to inorganic substance  negative regulation of peptidase activity  negative regulation of histolysis  negative regulation of collagen catabolic process  negative regulation of extracellular matrix disassembly  negative regulation of endopeptidase activity  response to nutrient levels  nuclear membrane  vesicle  response to estradiol stimulus  axon part  regulation of tissue remodeling  response to drug  circadian sleep/wake cycle, REM sleep  neuronal cell body  regulation of programmed cell death  extracellular fibril organization  contractile fiber  positive regulation of DNA replication  perinuclear region of cytoplasm  response to axon injury  Sertoli cell development  negative regulation of elastin catabolic process  negative regulation of blood vessel remodeling  negative regulation of cell death  cellular response to hydrogen peroxide  
Ontology : EGO-EBIbeta-amyloid binding  eye development  response to hypoxia  cell activation  protease binding  endopeptidase inhibitor activity  cysteine-type endopeptidase inhibitor activity  protein binding  extracellular region  extracellular region  basement membrane  extracellular space  lysosome  multivesicular body  endoplasmic reticulum  apoptotic process  defense response  brain development  salivary gland development  embryo implantation  positive regulation of cell proliferation  response to toxin  response to carbohydrate stimulus  response to inorganic substance  negative regulation of peptidase activity  negative regulation of histolysis  negative regulation of collagen catabolic process  negative regulation of extracellular matrix disassembly  negative regulation of endopeptidase activity  response to nutrient levels  nuclear membrane  vesicle  response to estradiol stimulus  axon part  regulation of tissue remodeling  response to drug  circadian sleep/wake cycle, REM sleep  neuronal cell body  regulation of programmed cell death  extracellular fibril organization  contractile fiber  positive regulation of DNA replication  perinuclear region of cytoplasm  response to axon injury  Sertoli cell development  negative regulation of elastin catabolic process  negative regulation of blood vessel remodeling  negative regulation of cell death  cellular response to hydrogen peroxide  
Other databases
Probes
Litterature
PubMed262 Pubmed reference(s) in Entrez
PubGeneCST3
iHOPCST3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:48:52 CEST 2013
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