CTNNAL1 (catenin alpha like 1)

2003-02-01  

Identity

HGNC
LOCATION
9q31.3
LOCUSID
ALIAS
ACRP,CLLP,alpha-CATU
FUSION GENES

Other Information

Locus ID:

NCBI: 8727
MIM: 604785
HGNC: 2512
Ensembl: ENSG00000119326

Variants:

dbSNP: 8727
ClinVar: 8727
TCGA: ENSG00000119326
COSMIC: CTNNAL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000119326ENST00000325551Q9UBT7
ENSG00000119326ENST00000374593Q5JTQ6
ENSG00000119326ENST00000374594Q5JTQ9
ENSG00000119326ENST00000374595Q9UBT7

Expression (GTEx)

0
50
100
150
200
250

References

Pubmed IDYearTitleCitations
122709172002Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation.23
149932802004Distinct activities of the alpha-catenin family, alpha-catulin and alpha-catenin, on beta-catenin-mediated signaling.18
211158372010Alpha-dystrobrevin-1 recruits alpha-catulin to the alpha1D-adrenergic receptor/dystrophin-associated protein complex signalosome.18
183744112008Seven placental transcripts characterize HELLP-syndrome.16
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.16
227334552013α-Catulin downregulates E-cadherin and promotes melanoma progression and invasion.16
179521172008Alpha-catulin, a Rho signalling component, can regulate NF-kappaB through binding to IKK-beta, and confers resistance to apoptosis.15
230478662013α-Catulin drives metastasis by activating ILK and driving an αvβ3 integrin signaling axis.13
206967642010The Lbc Rho guanine nucleotide exchange factor α-catulin axis functions in serotonin-induced vascular smooth muscle cell mitogenesis and RhoA/ROCK activation.11
226487982012α-Catulin marks the invasion front of squamous cell carcinoma and is important for tumor cell metastasis.9

Citation

Dessen P

CTNNAL1 (catenin alpha like 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40194/ctnnal1