Identity
HGNC
LOCATION
9q31.3
LOCUSID
ALIAS
ACRP,CLLP,alpha-CATU
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8727
MIM: 604785
HGNC: 2512
Ensembl: ENSG00000119326
Variants:
dbSNP: 8727
ClinVar: 8727
TCGA: ENSG00000119326
COSMIC: CTNNAL1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000119326 | ENST00000325551 | Q9UBT7 |
| ENSG00000119326 | ENST00000374593 | Q5JTQ6 |
| ENSG00000119326 | ENST00000374594 | Q5JTQ9 |
| ENSG00000119326 | ENST00000374595 | Q9UBT7 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37715489 | 2023 | CTNNAL1 deficiency suppresses CFTR expression in HDM-induced asthma mouse model through ROCK1-CAL signaling pathway. | 1 |
| 37715489 | 2023 | CTNNAL1 deficiency suppresses CFTR expression in HDM-induced asthma mouse model through ROCK1-CAL signaling pathway. | 1 |
| 35154481 | 2022 | α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer. | 9 |
| 35154481 | 2022 | α-Catulin promotes cancer stemness by antagonizing WWP1-mediated KLF5 degradation in lung cancer. | 9 |
| 32139661 | 2020 | Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease. | 4 |
| 32139661 | 2020 | Genetic variants in RET, ARHGEF3 and CTNNAL1, and relevant interaction networks, contribute to the risk of Hirschsprung disease. | 4 |
| 29791759 | 2018 | CTNNAL1 inhibits ozone-induced epithelial-mesenchymal transition in human bronchial epithelial cells. | 10 |
| 29791759 | 2018 | CTNNAL1 inhibits ozone-induced epithelial-mesenchymal transition in human bronchial epithelial cells. | 10 |
| 26311049 | 2016 | The upregulated α-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition. | 3 |
| 26311049 | 2016 | The upregulated α-catulin expression was involved in head-neck squamous cell carcinogenesis by promoting proliferation, migration, invasion, and epithelial to mesenchymal transition. | 3 |
| 25793618 | 2015 | Alpha-catulin contributes to drug-resistance of melanoma by activating NF-κB and AP-1. | 14 |
| 25793618 | 2015 | Alpha-catulin contributes to drug-resistance of melanoma by activating NF-κB and AP-1. | 14 |
| 22733455 | 2013 | α-Catulin downregulates E-cadherin and promotes melanoma progression and invasion. | 21 |
| 23047866 | 2013 | α-Catulin drives metastasis by activating ILK and driving an αvβ3 integrin signaling axis. | 21 |
| 22733455 | 2013 | α-Catulin downregulates E-cadherin and promotes melanoma progression and invasion. | 21 |
Citation
Dessen P
CTNNAL1 (catenin alpha like 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/40194/ctnnal1
