Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CUL4B (cullin 4B)

Identity

Other namesMRXHF2
MRXS15
MRXSC
SFM2
HGNC (Hugo) CUL4B
LocusID (NCBI) 8450
Location Xq24
Location_base_pair Starts at 119658446 and ends at 119694817 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CUL4B   2555
Cards
Entrez_Gene (NCBI)CUL4B  8450  cullin 4B
GeneCards (Weizmann)CUL4B
Ensembl (Hinxton)ENSG00000158290 [Gene_View]  chrX:119658446-119694817 [Contig_View]  CUL4B [Vega]
AceView (NCBI)CUL4B
Genatlas (Paris)CUL4B
WikiGenes8450
SOURCE (Princeton)NM_001079872 NM_003588
Genomic and cartography
GoldenPath (UCSC)CUL4B  -  Xq24   chrX:119658446-119694817 -  Xq24   [Description]    (hg19-Feb_2009)
EnsemblCUL4B - Xq24 [CytoView]
Mapping of homologs : NCBICUL4B [Mapview]
OMIM300304   300354   300639   
Gene and transcription
Genbank (Entrez)AB014595 AF212995 AK123688 AK299081 AK315037
RefSeq transcript (Entrez)NM_001079872 NM_003588
RefSeq genomic (Entrez)AC_000155 NC_000023 NC_018934 NG_009388 NT_011786 NW_001842396 NW_004929446
Consensus coding sequences : CCDS (NCBI)CUL4B
Cluster EST : UnigeneHs.102914 [ NCBI ]
CGAP (NCI)Hs.102914
Alternative Splicing : Fast-db (Paris)GSHG0032306
Alternative Splicing GalleryENSG00000158290
Gene ExpressionCUL4B [ NCBI-GEO ]     CUL4B [ SEEK ]   CUL4B [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13620 (Uniprot)
NextProtQ13620  [Medical]
With graphics : InterProQ13620
Splice isoforms : SwissVarQ13620 (Swissvar)
Domaine pattern : Prosite (Expaxy)CULLIN_1 (PS01256)    CULLIN_2 (PS50069)   
Domains : Interpro (EBI)Cullin_CS    Cullin_homology    Cullin_N    Cullin_neddylation_domain    Cullin_repeat-like_dom    WHTH_DNA-bd_dom   
Related proteins : CluSTrQ13620
Domain families : Pfam (Sanger)Cullin (PF00888)    Cullin_Nedd8 (PF10557)   
Domain families : Pfam (NCBI)pfam00888    pfam10557   
Domain families : Smart (EMBL)CULLIN (SM00182)  Cullin_Nedd8 (SM00884)  
DMDM Disease mutations8450
Blocks (Seattle)Q13620
PDB (SRS)2DO7    4A0C    4A0L    4A64   
PDB (PDBSum)2DO7    4A0C    4A0L    4A64   
PDB (IMB)2DO7    4A0C    4A0L    4A64   
PDB (RSDB)2DO7    4A0C    4A0L    4A64   
Human Protein AtlasENSG00000158290
Peptide AtlasQ13620
HPRD02251
IPIIPI00179057   IPI00480142   IPI00965290   IPI00643885   IPI00644450   
Protein Interaction databases
DIP (DOE-UCLA)Q13620
IntAct (EBI)Q13620
FunCoupENSG00000158290
BioGRIDCUL4B
InParanoidQ13620
Interologous Interaction database Q13620
IntegromeDBCUL4B
STRING (EMBL)CUL4B
Ontologies - Pathways
Ontology : AmiGOprotein binding  nucleus  nucleolus  plasma membrane  DNA repair  ubiquitin-dependent protein catabolic process  cell cycle  protein ubiquitination  Cul4B-RING ubiquitin ligase complex  ubiquitin protein ligase binding  positive regulation of protein catabolic process  
Ontology : EGO-EBIprotein binding  nucleus  nucleolus  plasma membrane  DNA repair  ubiquitin-dependent protein catabolic process  cell cycle  protein ubiquitination  Cul4B-RING ubiquitin ligase complex  ubiquitin protein ligase binding  positive regulation of protein catabolic process  
Pathways : KEGGNucleotide excision repair    Ubiquitin mediated proteolysis   
REACTOMECUL4B
Protein Interaction DatabaseCUL4B
Wikipedia pathwaysCUL4B
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CUL4B
SNP (GeneSNP Utah)CUL4B
SNP : HGBaseCUL4B
Genetic variants : HAPMAPCUL4B
1000_GenomesCUL4B 
ICGC programENSG00000158290 
Somatic Mutations in Cancer : COSMICCUL4B 
CONAN: Copy Number AnalysisCUL4B 
Mutations and Diseases : HGMDCUL4B
OMIM300304    300354    300639   
GENETestsCUL4B
Disease Genetic AssociationCUL4B
Huge Navigator CUL4B [HugePedia]  CUL4B [HugeCancerGEM]
Genomic VariantsCUL4B  CUL4B [DGVbeta]
Exome VariantCUL4B
dbVarCUL4B
ClinVarCUL4B
snp3D : Map Gene to Disease8450
General knowledge
Homologs : HomoloGeneCUL4B
Homology/Alignments : Family Browser (UCSC)CUL4B
Phylogenetic Trees/Animal Genes : TreeFamCUL4B
Chemical/Protein Interactions : CTD8450
Chemical/Pharm GKB GenePA27051
Clinical trialCUL4B
Cancer Resource (Charite)ENSG00000158290
Other databases
Probes
Litterature
PubMed81 Pubmed reference(s) in Entrez
CoreMineCUL4B
iHOPCUL4B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 16:52:23 CEST 2014

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