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CYP2F1 (cytochrome P450 family 2 subfamily F member 1)

Identity

Alias_namesCYP2F
cytochrome P450, subfamily IIF, polypeptide 1
cytochrome P450, family 2, subfamily F, polypeptide 1
Other aliasC2F1
CYPIIF1
HGNC (Hugo) CYP2F1
LocusID (NCBI) 1572
Atlas_Id 47587
Location 19q13.2  [Link to chromosome band 19q13]
Location_base_pair Starts at 41114432 and ends at 41128381 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CYP2F1   2632
Cards
Entrez_Gene (NCBI)CYP2F1  1572  cytochrome P450 family 2 subfamily F member 1
AliasesC2F1; CYP2F; CYPIIF1
GeneCards (Weizmann)CYP2F1
Ensembl hg19 (Hinxton)ENSG00000197446 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197446 [Gene_View]  chr19:41114432-41128381 [Contig_View]  CYP2F1 [Vega]
ICGC DataPortalENSG00000197446
TCGA cBioPortalCYP2F1
AceView (NCBI)CYP2F1
Genatlas (Paris)CYP2F1
WikiGenes1572
SOURCE (Princeton)CYP2F1
Genetics Home Reference (NIH)CYP2F1
Genomic and cartography
GoldenPath hg38 (UCSC)CYP2F1  -     chr19:41114432-41128381 +  19q13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CYP2F1  -     19q13.2   [Description]    (hg19-Feb_2009)
EnsemblCYP2F1 - 19q13.2 [CytoView hg19]  CYP2F1 - 19q13.2 [CytoView hg38]
Mapping of homologs : NCBICYP2F1 [Mapview hg19]  CYP2F1 [Mapview hg38]
OMIM124070   
Gene and transcription
Genbank (Entrez)AK296884 AK298082 AK316498 BC109056 BC109057
RefSeq transcript (Entrez)NM_000774
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CYP2F1
Cluster EST : UnigeneHs.676472 [ NCBI ]
CGAP (NCI)Hs.676472
Alternative Splicing GalleryENSG00000197446
Gene ExpressionCYP2F1 [ NCBI-GEO ]   CYP2F1 [ EBI - ARRAY_EXPRESS ]   CYP2F1 [ SEEK ]   CYP2F1 [ MEM ]
Gene Expression Viewer (FireBrowse)CYP2F1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1572
GTEX Portal (Tissue expression)CYP2F1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP24903   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP24903  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP24903
Splice isoforms : SwissVarP24903
PhosPhoSitePlusP24903
Domaine pattern : Prosite (Expaxy)CYTOCHROME_P450 (PS00086)   
Domains : Interpro (EBI)Cyt_P450    Cyt_P450_CS    Cyt_P450_CYP2_fam    Cyt_P450_E_grp-I   
Domain families : Pfam (Sanger)p450 (PF00067)   
Domain families : Pfam (NCBI)pfam00067   
Conserved Domain (NCBI)CYP2F1
DMDM Disease mutations1572
Blocks (Seattle)CYP2F1
SuperfamilyP24903
Human Protein AtlasENSG00000197446
Peptide AtlasP24903
HPRD00490
IPIIPI00103355   IPI00655573   IPI01013134   
Protein Interaction databases
DIP (DOE-UCLA)P24903
IntAct (EBI)P24903
FunCoupENSG00000197446
BioGRIDCYP2F1
STRING (EMBL)CYP2F1
ZODIACCYP2F1
Ontologies - Pathways
QuickGOP24903
Ontology : AmiGOmonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  xenobiotic metabolic process  arachidonic acid epoxygenase activity  response to toxic substance  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen  naphthalene metabolic process  trichloroethylene metabolic process  epoxygenase P450 pathway  oxygen binding  heme binding  organelle membrane  intracellular membrane-bounded organelle  oxidation-reduction process  aromatase activity  
Ontology : EGO-EBImonooxygenase activity  iron ion binding  endoplasmic reticulum membrane  xenobiotic metabolic process  arachidonic acid epoxygenase activity  response to toxic substance  oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen  naphthalene metabolic process  trichloroethylene metabolic process  epoxygenase P450 pathway  oxygen binding  heme binding  organelle membrane  intracellular membrane-bounded organelle  oxidation-reduction process  aromatase activity  
Pathways : KEGGMetabolism of xenobiotics by cytochrome P450   
NDEx NetworkCYP2F1
Atlas of Cancer Signalling NetworkCYP2F1
Wikipedia pathwaysCYP2F1
Orthology - Evolution
OrthoDB1572
GeneTree (enSembl)ENSG00000197446
Phylogenetic Trees/Animal Genes : TreeFamCYP2F1
HOVERGENP24903
HOGENOMP24903
Homologs : HomoloGeneCYP2F1
Homology/Alignments : Family Browser (UCSC)CYP2F1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCYP2F1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CYP2F1
dbVarCYP2F1
ClinVarCYP2F1
1000_GenomesCYP2F1 
Exome Variant ServerCYP2F1
ExAC (Exome Aggregation Consortium)CYP2F1 (select the gene name)
Genetic variants : HAPMAP1572
Genomic Variants (DGV)CYP2F1 [DGVbeta]
DECIPHERCYP2F1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCYP2F1 
Mutations
ICGC Data PortalCYP2F1 
TCGA Data PortalCYP2F1 
Broad Tumor PortalCYP2F1
OASIS PortalCYP2F1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCYP2F1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCYP2F1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch CYP2F1
DgiDB (Drug Gene Interaction Database)CYP2F1
DoCM (Curated mutations)CYP2F1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CYP2F1 (select a term)
intoGenCYP2F1
Cancer3DCYP2F1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM124070   
Orphanet
MedgenCYP2F1
Genetic Testing Registry CYP2F1
NextProtP24903 [Medical]
TSGene1572
GENETestsCYP2F1
Target ValidationCYP2F1
Huge Navigator CYP2F1 [HugePedia]
snp3D : Map Gene to Disease1572
BioCentury BCIQCYP2F1
ClinGenCYP2F1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1572
Chemical/Pharm GKB GenePA27109
Clinical trialCYP2F1
Miscellaneous
canSAR (ICR)CYP2F1 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCYP2F1
EVEXCYP2F1
GoPubMedCYP2F1
iHOPCYP2F1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 16:59:06 CEST 2017

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