CYP2F1 (cytochrome P450 family 2 subfamily F member 1)

2007-07-01  

Identity

HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
C2F1,CYP2F,CYPIIF1

Other Information

Locus ID:

NCBI: 1572
MIM: 124070
HGNC: 2632
Ensembl: ENSG00000197446

Variants:

dbSNP: 1572
ClinVar: 1572
TCGA: ENSG00000197446
COSMIC: CYP2F1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197446ENST00000331105P24903
ENSG00000197446ENST00000439903H0YGI9
ENSG00000197446ENST00000532164P24903
ENSG00000197446ENST00000534009A0A075B795

Expression (GTEx)

0
1
2
3
4

Pathways

PathwaySourceExternal ID
Metabolism of xenobiotics by cytochrome P450KEGGko00980
Metabolism of xenobiotics by cytochrome P450KEGGhsa00980
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase 1 - Functionalization of compoundsREACTOMER-HSA-211945
Cytochrome P450 - arranged by substrate typeREACTOMER-HSA-211897
XenobioticsREACTOMER-HSA-211981
CYP2E1 reactionsREACTOMER-HSA-211999
Fatty acidsREACTOMER-HSA-211935

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA10804imatinibChemicalClinicalAnnotationassociatedPD30237583
PA151958383Gastrointestinal Stromal TumorsDiseaseClinicalAnnotationassociatedPD30237583

References

Pubmed IDYearTitleCitations
291714552017Association between effectiveness of tuberculosis treatment and cytochrome P-4502E1 polymorphism of the patients.2
291714552017Association between effectiveness of tuberculosis treatment and cytochrome P-4502E1 polymorphism of the patients.2
223978532012Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse model.18
223978532012Generation and characterization of a CYP2A13/2B6/2F1-transgenic mouse model.18
222329292011[Polymorphic markers of the CYP1B1 (4326C > G), CYP2F1 (c.14_15insC), CYP2J2 (-76G > T), and CYP2S1 (13106C > T and 13255A > G) genes and genetic predisposition to chronic respiratory diseases induced by smoking and occupational factors].1
222329292011[Polymorphic markers of the CYP1B1 (4326C > G), CYP2F1 (c.14_15insC), CYP2J2 (-76G > T), and CYP2S1 (13106C > T and 13255A > G) genes and genetic predisposition to chronic respiratory diseases induced by smoking and occupational factors].1
201988572010[The CYP1B1 and CYP2F1 genes polymorphisms frequency in three ethnic groups of Bashkortostan and chronic obstructive pulmonary disease patients].2
201988572010[The CYP1B1 and CYP2F1 genes polymorphisms frequency in three ethnic groups of Bashkortostan and chronic obstructive pulmonary disease patients].2
201988572010[The CYP1B1 and CYP2F1 genes polymorphisms frequency in three ethnic groups of Bashkortostan and chronic obstructive pulmonary disease patients].2
201988572010[The CYP1B1 and CYP2F1 genes polymorphisms frequency in three ethnic groups of Bashkortostan and chronic obstructive pulmonary disease patients].2
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.4
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.4
173271312007Molecular analysis of the CYP2F1 gene: identification of a frequent non-functional allelic variant.6
173271312007Molecular analysis of the CYP2F1 gene: identification of a frequent non-functional allelic variant.6
179436602007CYP2F1 genetic polymorphism: identification of interethnic variations.3

Citation

Dessen P

CYP2F1 (cytochrome P450 family 2 subfamily F member 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-07-01

Online version: http://atlasgeneticsoncology.org/gene/47587/cyp2f1