| DDB1 (11q12.2) / ADCY2 (5p15.31) | DDB1 (11q12.2) / DDB1 (11q12.2) | DDB1 (11q12.2) / FOXP1 (3p13) |
|
DDB1 (11q12.2) / MALAT1 (11q13.1) | DDB1 (11q12.2) / PPM1M (3p21.2) | DDB1 (11q12.2) / SIGMAR1 (9p13.3) |
|
DDB1 (11q12.2) / TMEM258 (11q12.2) | DDB1 (11q12.2) / ZNF408 (11p11.2) | PRPF19 (11q12.2) / DDB1 (11q12.2) |
|
RASSF4 (10q11.21) / DDB1 (11q12.2) | DDB1 11q12.2 C11orf10 | PRPF19 11q12.2 / DDB1 11q12.2 |
|
| Nomenclature |
HGNC (Hugo) | DDB1 2717 |
LRG (Locus Reference Genomic) | LRG_474 |
| Cards |
Entrez_Gene (NCBI) | DDB1 damage specific DNA binding protein 1 |
Aliases | DDBA; UV-DDB1; XAP1; XPCE; |
| XPE; XPE-BF |
GeneCards (Weizmann) | DDB1 |
Ensembl hg19 (Hinxton) | ENSG00000167986 [Gene_View] |
Ensembl hg38 (Hinxton) | ENSG00000167986 [Gene_View]  ENSG00000167986 [Sequence] chr11:61299452-61333105 [Contig_View] DDB1 [Vega] |
ICGC DataPortal | ENSG00000167986 |
TCGA cBioPortal | DDB1 |
AceView (NCBI) | DDB1 |
Genatlas (Paris) | DDB1 |
SOURCE (Princeton) | DDB1 |
Genetics Home Reference (NIH) | DDB1 |
| Genomic and cartography |
GoldenPath hg38 (UCSC) | DDB1 - chr11:61299452-61333105 - 11q12.2 [Description] (hg38-Dec_2013) |
GoldenPath hg19 (UCSC) | DDB1 - 11q12.2 [Description] (hg19-Feb_2009) |
GoldenPath | DDB1 - 11q12.2 [CytoView hg19] DDB1 - 11q12.2 [CytoView hg38] |
ImmunoBase | ENSG00000167986 |
genome Data Viewer NCBI | DDB1 [Mapview hg19] |
OMIM | 600045 |
| Gene and transcription |
Genbank (Entrez) | AA665872 AJ002955 AK294341 AK294493 AK299650 |
RefSeq transcript (Entrez) | NM_001923 |
RefSeq genomic (Entrez) | |
Consensus coding sequences : CCDS (NCBI) | DDB1 |
Alternative Splicing Gallery | ENSG00000167986 |
Gene Expression | DDB1 [ NCBI-GEO ] DDB1 [ EBI - ARRAY_EXPRESS ]
DDB1 [ SEEK ] DDB1 [ MEM ] |
Gene Expression Viewer (FireBrowse) | DDB1 [ Firebrowse - Broad ] |
Genevisible | Expression of DDB1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]   |
BioGPS (Tissue expression) | 1642 |
GTEX Portal (Tissue expression) | DDB1 |
Human Protein Atlas | ENSG00000167986-DDB1 [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
UniProt/SwissProt | Q16531 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
NextProt | Q16531 [Sequence] [Exons] [Medical] [Publications] |
With graphics : InterPro | Q16531 |
Splice isoforms : SwissVar | Q16531 |
PhosPhoSitePlus | Q16531 |
Domains : Interpro (EBI) | Cleavage/polyA-sp_fac_asu_C DDB1 WD40/YVTN_repeat-like_dom_sf WD40_repeat_dom_sf |
Domain families : Pfam (Sanger) | CPSF_A (PF03178) |
Domain families : Pfam (NCBI) | pfam03178 |
Conserved Domain (NCBI) | DDB1 |
Blocks (Seattle) | DDB1 |
PDB (RSDB) | 2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4CI1 4CI2 4CI3 4E54 4E5Z 4TZ4 5FQD 5HXB 5JK7 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6DSZ 6FCV 6H0F 6H0G 6PAI 6Q0R 6Q0V 6Q0W 6R8Y 6R8Z 6R90 6R91 6R92 6SJ7 6UD7 6UE5 |
PDB Europe | 2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4CI1 4CI2 4CI3 4E54 4E5Z 4TZ4 5FQD 5HXB 5JK7 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6DSZ 6FCV 6H0F 6H0G 6PAI 6Q0R 6Q0V 6Q0W 6R8Y 6R8Z 6R90 6R91 6R92 6SJ7 6UD7 6UE5 |
PDB (PDBSum) | 2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4CI1 4CI2 4CI3 4E54 4E5Z 4TZ4 5FQD 5HXB 5JK7 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6DSZ 6FCV 6H0F 6H0G 6PAI 6Q0R 6Q0V 6Q0W 6R8Y 6R8Z 6R90 6R91 6R92 6SJ7 6UD7 6UE5 |
PDB (IMB) | 2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4CI1 4CI2 4CI3 4E54 4E5Z 4TZ4 5FQD 5HXB 5JK7 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6DSZ 6FCV 6H0F 6H0G 6PAI 6Q0R 6Q0V 6Q0W 6R8Y 6R8Z 6R90 6R91 6R92 6SJ7 6UD7 6UE5 |
Structural Biology KnowledgeBase | 2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4CI1 4CI2 4CI3 4E54 4E5Z 4TZ4 5FQD 5HXB 5JK7 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6DSZ 6FCV 6H0F 6H0G 6PAI 6Q0R 6Q0V 6Q0W 6R8Y 6R8Z 6R90 6R91 6R92 6SJ7 6UD7 6UE5 |
SCOP (Structural Classification of Proteins) | 2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4CI1 4CI2 4CI3 4E54 4E5Z 4TZ4 5FQD 5HXB 5JK7 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6DSZ 6FCV 6H0F 6H0G 6PAI 6Q0R 6Q0V 6Q0W 6R8Y 6R8Z 6R90 6R91 6R92 6SJ7 6UD7 6UE5 |
CATH (Classification of proteins structures) | 2B5L 2B5M 2B5N 2HYE 3E0C 3EI1 3EI2 3EI3 3EI4 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E 4A08 4A09 4A0A 4A0B 4A0K 4A0L 4A11 4CI1 4CI2 4CI3 4E54 4E5Z 4TZ4 5FQD 5HXB 5JK7 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6DSZ 6FCV 6H0F 6H0G 6PAI 6Q0R 6Q0V 6Q0W 6R8Y 6R8Z 6R90 6R91 6R92 6SJ7 6UD7 6UE5 |
Superfamily | Q16531 |
Human Protein Atlas [tissue] | ENSG00000167986-DDB1 [tissue] |
Peptide Atlas | Q16531 |
HPRD | 10952 |
IPI | IPI00293464 IPI00909177 IPI00909008 IPI00909251 IPI00922069 IPI00942006 IPI00977083 IPI01010454 IPI01014884 IPI01015574 IPI01013521 IPI01013765 IPI01014222 IPI01011208 IPI01011629 IPI01011929 IPI01012348 |
| Protein Interaction databases |
DIP (DOE-UCLA) | Q16531 |
IntAct (EBI) | Q16531 |
BioGRID | DDB1 |
STRING (EMBL) | DDB1 |
ZODIAC | DDB1 |
| Ontologies - Pathways |
QuickGO | Q16531 |
Ontology : AmiGO | nucleotide-excision repair, DNA damage recognition nucleotide-excision repair, DNA duplex unwinding nuclear chromosome, telomeric region DNA binding damaged DNA binding protein binding extracellular space nucleus nucleus nucleoplasm nucleoplasm cytoplasm DNA repair transcription-coupled nucleotide-excision repair nucleotide-excision repair nucleotide-excision repair, preincision complex stabilization nucleotide-excision repair, preincision complex assembly nucleotide-excision repair, DNA incision, 3'-to lesion nucleotide-excision repair, DNA incision, 5'-to lesion ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process cellular response to DNA damage stimulus proteasomal protein catabolic process viral process Wnt signaling pathway protein ubiquitination protein ubiquitination protein binding, bridging cullin-RING ubiquitin ligase complex Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex protein-containing complex nucleotide-excision repair, DNA incision histone H2A monoubiquitination regulation of circadian rhythm DNA damage response, detection of DNA damage negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process post-translational protein modification protein-containing complex binding positive regulation of viral genome replication positive regulation of gluconeogenesis positive regulation of protein catabolic process positive regulation by virus of viral protein levels in host cell rhythmic process interaction with symbiont extracellular exosome global genome nucleotide-excision repair UV-damage excision repair WD40-repeat domain binding Cul4-RING E3 ubiquitin ligase complex Cul4-RING E3 ubiquitin ligase complex cullin family protein binding regulation of mitotic cell cycle phase transition positive regulation of viral release from host cell |
Ontology : EGO-EBI | nucleotide-excision repair, DNA damage recognition nucleotide-excision repair, DNA duplex unwinding nuclear chromosome, telomeric region DNA binding damaged DNA binding protein binding extracellular space nucleus nucleus nucleoplasm nucleoplasm cytoplasm DNA repair transcription-coupled nucleotide-excision repair nucleotide-excision repair nucleotide-excision repair, preincision complex stabilization nucleotide-excision repair, preincision complex assembly nucleotide-excision repair, DNA incision, 3'-to lesion nucleotide-excision repair, DNA incision, 5'-to lesion ubiquitin-dependent protein catabolic process ubiquitin-dependent protein catabolic process cellular response to DNA damage stimulus proteasomal protein catabolic process viral process Wnt signaling pathway protein ubiquitination protein ubiquitination protein binding, bridging cullin-RING ubiquitin ligase complex Cul4A-RING E3 ubiquitin ligase complex Cul4B-RING E3 ubiquitin ligase complex protein-containing complex nucleotide-excision repair, DNA incision histone H2A monoubiquitination regulation of circadian rhythm DNA damage response, detection of DNA damage negative regulation of apoptotic process proteasome-mediated ubiquitin-dependent protein catabolic process proteasome-mediated ubiquitin-dependent protein catabolic process post-translational protein modification protein-containing complex binding positive regulation of viral genome replication positive regulation of gluconeogenesis positive regulation of protein catabolic process positive regulation by virus of viral protein levels in host cell rhythmic process interaction with symbiont extracellular exosome global genome nucleotide-excision repair UV-damage excision repair WD40-repeat domain binding Cul4-RING E3 ubiquitin ligase complex Cul4-RING E3 ubiquitin ligase complex cullin family protein binding regulation of mitotic cell cycle phase transition positive regulation of viral release from host cell |
Pathways : KEGG | Nucleotide excision repair Ubiquitin mediated proteolysis Hepatitis B Viral carcinogenesis |
NDEx Network | DDB1 |
Atlas of Cancer Signalling Network | DDB1 |
Wikipedia pathways | DDB1 |
| Orthology - Evolution |
OrthoDB | 1642 |
GeneTree (enSembl) | ENSG00000167986 |
Phylogenetic Trees/Animal Genes : TreeFam | DDB1 |
HOGENOM | Q16531 |
Homologs : HomoloGene | DDB1 |
Homology/Alignments : Family Browser (UCSC) | DDB1 |
| Gene fusions - Rearrangements |
Fusion : Mitelman | DDB1/TMEM258 [11q12.2/11q12.2]   |
Fusion : Mitelman | PRPF19/DDB1 [11q12.2/11q12.2]   |
Fusion Portal | DDB1 11q12.2 C11orf10 BRCA |
Fusion Portal | PRPF19 11q12.2 DDB1 11q12.2 BRCA |
Fusion : Quiver | DDB1 |
| Polymorphisms : SNP and Copy number variants |
NCBI Variation Viewer | DDB1 [hg38] |
dbVar | DDB1 |
ClinVar | DDB1 |
Monarch | DDB1 |
1000_Genomes | DDB1 |
Exome Variant Server | DDB1 |
GNOMAD Browser | ENSG00000167986 |
Varsome Browser | DDB1 |
Genomic Variants (DGV) | DDB1 [DGVbeta] |
DECIPHER | DDB1 [patients] [syndromes] [variants] [genes] |
CONAN: Copy Number Analysis | DDB1 |
| Mutations |
ICGC Data Portal | DDB1 |
TCGA Data Portal | DDB1 |
Broad Tumor Portal | DDB1 |
OASIS Portal | DDB1 [ Somatic mutations - Copy number] |
Somatic Mutations in Cancer : COSMIC | DDB1 [overview] [genome browser] [tissue] [distribution] |
Somatic Mutations in Cancer : COSMIC3D | DDB1 |
Mutations and Diseases : HGMD | DDB1 |
LOVD (Leiden Open Variation Database) | Whole genome datasets |
LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
BioMuta | search DDB1 |
DgiDB (Drug Gene Interaction Database) | DDB1 |
DoCM (Curated mutations) | DDB1 (select the gene name) |
CIViC (Clinical Interpretations of Variants in Cancer) | DDB1 (select a term) |
intoGen | DDB1 |
Cancer3D | DDB1(select the gene name) |
Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
---|
OMIM | 600045 |
Orphanet | |
DisGeNET | DDB1 |
Medgen | DDB1 |
Genetic Testing Registry | DDB1
|
NextProt | Q16531 [Medical] |
GENETests | DDB1 |
Target Validation | DDB1 |
Huge Navigator |
DDB1 [HugePedia] |
ClinGen | DDB1 |
| Clinical trials, drugs, therapy |
---|
MyCancerGenome | DDB1 |
Protein Interactions : CTD | |
Pharm GKB Gene | PA27187 |
Pharos | Q16531 |
Clinical trial | DDB1 |
| Miscellaneous |
---|
canSAR (ICR) | DDB1 (select the gene name) |
Harmonizome | DDB1 |
DataMed Index | DDB1 |
| Probes |
---|
| Litterature |
---|
PubMed | 414 Pubmed reference(s) in Entrez |
GeneRIFs | Gene References Into Functions (Entrez) |
EVEX | DDB1 |