Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DDX49 (DEAD-box helicase 49)

Identity

Alias_namesDEAD (Asp-Glu-Ala-Asp) box polypeptide 49
Alias_symbol (synonym)FLJ10432
Other aliasR27090_2
HGNC (Hugo) DDX49
LocusID (NCBI) 54555
Atlas_Id 40289
Location 19p13.11  [Link to chromosome band 19p13]
Location_base_pair Starts at 18919675 and ends at 18928633 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EEF1A1 (6q13) / DDX49 (19p13.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DDX49   18684
Cards
Entrez_Gene (NCBI)DDX49  54555  DEAD-box helicase 49
AliasesR27090_2
GeneCards (Weizmann)DDX49
Ensembl hg19 (Hinxton)ENSG00000105671 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105671 [Gene_View]  chr19:18919675-18928633 [Contig_View]  DDX49 [Vega]
ICGC DataPortalENSG00000105671
TCGA cBioPortalDDX49
AceView (NCBI)DDX49
Genatlas (Paris)DDX49
WikiGenes54555
SOURCE (Princeton)DDX49
Genetics Home Reference (NIH)DDX49
Genomic and cartography
GoldenPath hg38 (UCSC)DDX49  -     chr19:18919675-18928633 +  19p13.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DDX49  -     19p13.11   [Description]    (hg19-Feb_2009)
EnsemblDDX49 - 19p13.11 [CytoView hg19]  DDX49 - 19p13.11 [CytoView hg38]
Mapping of homologs : NCBIDDX49 [Mapview hg19]  DDX49 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK001294 AK223294 AK291916 AL110272 AL137702
RefSeq transcript (Entrez)NM_019070
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DDX49
Cluster EST : UnigeneHs.143187 [ NCBI ]
CGAP (NCI)Hs.143187
Alternative Splicing GalleryENSG00000105671
Gene ExpressionDDX49 [ NCBI-GEO ]   DDX49 [ EBI - ARRAY_EXPRESS ]   DDX49 [ SEEK ]   DDX49 [ MEM ]
Gene Expression Viewer (FireBrowse)DDX49 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54555
GTEX Portal (Tissue expression)DDX49
Human Protein AtlasENSG00000105671-DDX49 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6V7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6V7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6V7
Splice isoforms : SwissVarQ9Y6V7
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ9Y6V7
Domaine pattern : Prosite (Expaxy)DEAD_ATP_HELICASE (PS00039)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase    RNA-helicase_DEAD-box_CS    RNA_helicase_DEAD_Q_motif   
Domain families : Pfam (Sanger)DEAD (PF00270)    Helicase_C (PF00271)   
Domain families : Pfam (NCBI)pfam00270    pfam00271   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
Conserved Domain (NCBI)DDX49
DMDM Disease mutations54555
Blocks (Seattle)DDX49
SuperfamilyQ9Y6V7
Human Protein Atlas [tissue]ENSG00000105671-DDX49 [tissue]
Peptide AtlasQ9Y6V7
HPRD10864
IPIIPI00003739   IPI00012192   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6V7
IntAct (EBI)Q9Y6V7
FunCoupENSG00000105671
BioGRIDDDX49
STRING (EMBL)DDX49
ZODIACDDX49
Ontologies - Pathways
QuickGOQ9Y6V7
Ontology : AmiGORNA binding  ATP-dependent RNA helicase activity  ATP binding  nucleoplasm  rRNA processing  RNA secondary structure unwinding  
Ontology : EGO-EBIRNA binding  ATP-dependent RNA helicase activity  ATP binding  nucleoplasm  rRNA processing  RNA secondary structure unwinding  
NDEx NetworkDDX49
Atlas of Cancer Signalling NetworkDDX49
Wikipedia pathwaysDDX49
Orthology - Evolution
OrthoDB54555
GeneTree (enSembl)ENSG00000105671
Phylogenetic Trees/Animal Genes : TreeFamDDX49
HOVERGENQ9Y6V7
HOGENOMQ9Y6V7
Homologs : HomoloGeneDDX49
Homology/Alignments : Family Browser (UCSC)DDX49
Gene fusions - Rearrangements
Tumor Fusion PortalDDX49
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDX49 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDX49
dbVarDDX49
ClinVarDDX49
1000_GenomesDDX49 
Exome Variant ServerDDX49
ExAC (Exome Aggregation Consortium)ENSG00000105671
GNOMAD BrowserENSG00000105671
Genetic variants : HAPMAP54555
Genomic Variants (DGV)DDX49 [DGVbeta]
DECIPHERDDX49 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDDX49 
Mutations
ICGC Data PortalDDX49 
TCGA Data PortalDDX49 
Broad Tumor PortalDDX49
OASIS PortalDDX49 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDX49  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDX49
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DDX49
DgiDB (Drug Gene Interaction Database)DDX49
DoCM (Curated mutations)DDX49 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDX49 (select a term)
intoGenDDX49
Cancer3DDDX49(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETDDX49
MedgenDDX49
Genetic Testing Registry DDX49
NextProtQ9Y6V7 [Medical]
TSGene54555
GENETestsDDX49
Target ValidationDDX49
Huge Navigator DDX49 [HugePedia]
snp3D : Map Gene to Disease54555
BioCentury BCIQDDX49
ClinGenDDX49
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54555
Chemical/Pharm GKB GenePA134956171
Clinical trialDDX49
Miscellaneous
canSAR (ICR)DDX49 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDX49
EVEXDDX49
GoPubMedDDX49
iHOPDDX49
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:10:16 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.