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DISC1 (DISC1 scaffold protein)

Identity

Alias (NCBI)C1orf136
SCZD9
HGNC (Hugo) DISC1
HGNC Previous namedisrupted in schizophrenia 1
LocusID (NCBI) 27185
Atlas_Id 46081
Location 1q42.2  [Link to chromosome band 1q42]
Location_base_pair Starts at 231626790 and ends at 232041272 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LYST (1q42.3) / DISC1 (1q42.2)OBSCN (1q42.13) / DISC1 (1q42.2)PBX1 (1q23.3) / DISC1 (1q42.2)
TSNAX (1q42.2) / DISC1 (1q42.2)LYST 1q42.3 / DISC1 1q42.2OBSCN 1q42.13 / DISC1 1q42.2
PBX1 1q23.3 / DISC1 1q42.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(5;16)(q32;p13) NDE1/PDGFRB


External links

Nomenclature
HGNC (Hugo)DISC1   2888
Cards
Entrez_Gene (NCBI)DISC1    DISC1 scaffold protein
AliasesC1orf136; SCZD9
GeneCards (Weizmann)DISC1
Ensembl hg19 (Hinxton)ENSG00000162946 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162946 [Gene_View]  ENSG00000162946 [Sequence]  chr1:231626790-232041272 [Contig_View]  DISC1 [Vega]
ICGC DataPortalENSG00000162946
TCGA cBioPortalDISC1
AceView (NCBI)DISC1
Genatlas (Paris)DISC1
SOURCE (Princeton)DISC1
Genetics Home Reference (NIH)DISC1
Genomic and cartography
GoldenPath hg38 (UCSC)DISC1  -     chr1:231626790-232041272 +  1q42.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DISC1  -     1q42.2   [Description]    (hg19-Feb_2009)
GoldenPathDISC1 - 1q42.2 [CytoView hg19]  DISC1 - 1q42.2 [CytoView hg38]
ImmunoBaseENSG00000162946
Genome Data Viewer NCBIDISC1 [Mapview hg19]  
OMIM604906   605210   
Gene and transcription
Genbank (Entrez)AB007926 AF222980 AI075754 AJ506177 AJ506178
RefSeq transcript (Entrez)NM_001012957 NM_001012958 NM_001012959 NM_001039383 NM_001164537 NM_001164538 NM_001164539 NM_001164540 NM_001164541 NM_001164542 NM_001164544 NM_001164545 NM_001164546 NM_001164547 NM_001164548 NM_001164549 NM_001164550 NM_001164551 NM_001164552 NM_001164553 NM_001164554 NM_001164555 NM_001164556 NM_018662
Consensus coding sequences : CCDS (NCBI)DISC1
Gene ExpressionDISC1 [ NCBI-GEO ]   DISC1 [ EBI - ARRAY_EXPRESS ]   DISC1 [ SEEK ]   DISC1 [ MEM ]
Gene Expression Viewer (FireBrowse)DISC1 [ Firebrowse - Broad ]
GenevisibleExpression of DISC1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27185
GTEX Portal (Tissue expression)DISC1
Human Protein AtlasENSG00000162946-DISC1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)DISC1
Human Protein Atlas [tissue]ENSG00000162946-DISC1 [tissue]
HPRD05553
Protein Interaction databases
BioGRIDDISC1
STRING (EMBL)DISC1
ZODIACDISC1
Ontologies - Pathways
Litterature
PubMed277 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDISC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:06:47 CEST 2021

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