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DKK4 (dickkopf WNT signaling pathway inhibitor 4)

Identity

Alias_namesdickkopf (Xenopus laevis) homolog 4
dickkopf homolog 4 (Xenopus laevis)
Other aliasDKK-4
HGNC (Hugo) DKK4
LocusID (NCBI) 27121
Atlas_Id 50347
Location 8p11.21  [Link to chromosome band 8p11]
Location_base_pair Starts at 42231586 and ends at 42234674 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DKK4   2894
Cards
Entrez_Gene (NCBI)DKK4  27121  dickkopf WNT signaling pathway inhibitor 4
AliasesDKK-4
GeneCards (Weizmann)DKK4
Ensembl hg19 (Hinxton)ENSG00000104371 [Gene_View]  chr8:42231586-42234674 [Contig_View]  DKK4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104371 [Gene_View]  chr8:42231586-42234674 [Contig_View]  DKK4 [Vega]
ICGC DataPortalENSG00000104371
TCGA cBioPortalDKK4
AceView (NCBI)DKK4
Genatlas (Paris)DKK4
WikiGenes27121
SOURCE (Princeton)DKK4
Genetics Home Reference (NIH)DKK4
Genomic and cartography
GoldenPath hg19 (UCSC)DKK4  -     chr8:42231586-42234674 -  8p11.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DKK4  -     8p11.21   [Description]    (hg38-Dec_2013)
EnsemblDKK4 - 8p11.21 [CytoView hg19]  DKK4 - 8p11.21 [CytoView hg38]
Mapping of homologs : NCBIDKK4 [Mapview hg19]  DKK4 [Mapview hg38]
OMIM605417   
Gene and transcription
Genbank (Entrez)AB017788 AF177397 AK301609 BC107046 BC107047
RefSeq transcript (Entrez)NM_014420
RefSeq genomic (Entrez)NC_000008 NC_018919 NT_167187 NW_004929337
Consensus coding sequences : CCDS (NCBI)DKK4
Cluster EST : UnigeneHs.159311 [ NCBI ]
CGAP (NCI)Hs.159311
Alternative Splicing GalleryENSG00000104371
Gene ExpressionDKK4 [ NCBI-GEO ]   DKK4 [ EBI - ARRAY_EXPRESS ]   DKK4 [ SEEK ]   DKK4 [ MEM ]
Gene Expression Viewer (FireBrowse)DKK4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27121
GTEX Portal (Tissue expression)DKK4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBT3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UBT3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBT3
Splice isoforms : SwissVarQ9UBT3
PhosPhoSitePlusQ9UBT3
Domains : Interpro (EBI)Dickkopf_N    Prokineticin_domain   
Domain families : Pfam (Sanger)Dickkopf_N (PF04706)    Prokineticin (PF06607)   
Domain families : Pfam (NCBI)pfam04706    pfam06607   
Domain structure : Prodom (Prabi Lyon)Prokineticin (PD059788)   
Conserved Domain (NCBI)DKK4
DMDM Disease mutations27121
Blocks (Seattle)DKK4
SuperfamilyQ9UBT3
Human Protein AtlasENSG00000104371
Peptide AtlasQ9UBT3
HPRD05660
IPIIPI00002771   IPI01016000   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBT3
IntAct (EBI)Q9UBT3
FunCoupENSG00000104371
BioGRIDDKK4
STRING (EMBL)DKK4
ZODIACDKK4
Ontologies - Pathways
QuickGOQ9UBT3
Ontology : AmiGOmolecular_function  cellular_component  extracellular region  multicellular organism development  Wnt signaling pathway  negative regulation of Wnt signaling pathway  negative regulation of hair follicle placode formation  negative regulation of canonical Wnt signaling pathway  
Ontology : EGO-EBImolecular_function  cellular_component  extracellular region  multicellular organism development  Wnt signaling pathway  negative regulation of Wnt signaling pathway  negative regulation of hair follicle placode formation  negative regulation of canonical Wnt signaling pathway  
Pathways : KEGGWnt signaling pathway   
NDEx NetworkDKK4
Atlas of Cancer Signalling NetworkDKK4
Wikipedia pathwaysDKK4
Orthology - Evolution
OrthoDB27121
GeneTree (enSembl)ENSG00000104371
Phylogenetic Trees/Animal Genes : TreeFamDKK4
HOVERGENQ9UBT3
HOGENOMQ9UBT3
Homologs : HomoloGeneDKK4
Homology/Alignments : Family Browser (UCSC)DKK4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDKK4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DKK4
dbVarDKK4
ClinVarDKK4
1000_GenomesDKK4 
Exome Variant ServerDKK4
ExAC (Exome Aggregation Consortium)DKK4 (select the gene name)
Genetic variants : HAPMAP27121
Genomic Variants (DGV)DKK4 [DGVbeta]
DECIPHER (Syndromes)8:42231586-42234674  ENSG00000104371
CONAN: Copy Number AnalysisDKK4 
Mutations
ICGC Data PortalDKK4 
TCGA Data PortalDKK4 
Broad Tumor PortalDKK4
OASIS PortalDKK4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDKK4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDKK4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DKK4
DgiDB (Drug Gene Interaction Database)DKK4
DoCM (Curated mutations)DKK4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DKK4 (select a term)
intoGenDKK4
Cancer3DDKK4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605417   
Orphanet
MedgenDKK4
Genetic Testing Registry DKK4
NextProtQ9UBT3 [Medical]
TSGene27121
GENETestsDKK4
Huge Navigator DKK4 [HugePedia]
snp3D : Map Gene to Disease27121
BioCentury BCIQDKK4
ClinGenDKK4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27121
Chemical/Pharm GKB GenePA27348
Clinical trialDKK4
Miscellaneous
canSAR (ICR)DKK4 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDKK4
EVEXDKK4
GoPubMedDKK4
iHOPDKK4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:58:56 CEST 2017

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