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DPYSL5 (dihydropyrimidinase like 5)

Identity

Alias_namesdihydropyrimidinase-like 5
Alias_symbol (synonym)CRMP5
Ulip6
CRMP-5
CRAM
Other alias
HGNC (Hugo) DPYSL5
LocusID (NCBI) 56896
Atlas_Id 50119
Location 2p23.3  [Link to chromosome band 2p23]
Location_base_pair Starts at 27071157 and ends at 27173219 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ARPC3 (12q24.11) / DPYSL5 (2p23.3)BRE (2p23.2) / DPYSL5 (2p23.3)DPYSL5 (2p23.3) / RNF103-CHMP3 (2p11.2)
HIGD2A (5q35.2) / DPYSL5 (2p23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DPYSL5   20637
Cards
Entrez_Gene (NCBI)DPYSL5  56896  dihydropyrimidinase like 5
AliasesCRAM; CRMP-5; CRMP5; Ulip6
GeneCards (Weizmann)DPYSL5
Ensembl hg19 (Hinxton)ENSG00000157851 [Gene_View]  chr2:27071157-27173219 [Contig_View]  DPYSL5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000157851 [Gene_View]  chr2:27071157-27173219 [Contig_View]  DPYSL5 [Vega]
ICGC DataPortalENSG00000157851
TCGA cBioPortalDPYSL5
AceView (NCBI)DPYSL5
Genatlas (Paris)DPYSL5
WikiGenes56896
SOURCE (Princeton)DPYSL5
Genetics Home Reference (NIH)DPYSL5
Genomic and cartography
GoldenPath hg19 (UCSC)DPYSL5  -     chr2:27071157-27173219 +  2p23.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DPYSL5  -     2p23.3   [Description]    (hg38-Dec_2013)
EnsemblDPYSL5 - 2p23.3 [CytoView hg19]  DPYSL5 - 2p23.3 [CytoView hg38]
Mapping of homologs : NCBIDPYSL5 [Mapview hg19]  DPYSL5 [Mapview hg38]
OMIM608383   
Gene and transcription
Genbank (Entrez)AF157634 AF264015 AJ251275 AK022795 AK127314
RefSeq transcript (Entrez)NM_001253723 NM_001253724 NM_020134
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_022184 NW_004929300
Consensus coding sequences : CCDS (NCBI)DPYSL5
Cluster EST : UnigeneHs.299315 [ NCBI ]
CGAP (NCI)Hs.299315
Alternative Splicing GalleryENSG00000157851
Gene ExpressionDPYSL5 [ NCBI-GEO ]   DPYSL5 [ EBI - ARRAY_EXPRESS ]   DPYSL5 [ SEEK ]   DPYSL5 [ MEM ]
Gene Expression Viewer (FireBrowse)DPYSL5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56896
GTEX Portal (Tissue expression)DPYSL5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BPU6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BPU6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BPU6
Splice isoforms : SwissVarQ9BPU6
PhosPhoSitePlusQ9BPU6
Domains : Interpro (EBI)Amidohydro-rel    DRP5    Hydantoinase/dihydroPyrase    Metal-dep_hydrolase_composite    Metal_Hydrolase   
Domain families : Pfam (Sanger)Amidohydro_1 (PF01979)   
Domain families : Pfam (NCBI)pfam01979   
Conserved Domain (NCBI)DPYSL5
DMDM Disease mutations56896
Blocks (Seattle)DPYSL5
PDB (SRS)4B90    4B91    4B92   
PDB (PDBSum)4B90    4B91    4B92   
PDB (IMB)4B90    4B91    4B92   
PDB (RSDB)4B90    4B91    4B92   
Structural Biology KnowledgeBase4B90    4B91    4B92   
SCOP (Structural Classification of Proteins)4B90    4B91    4B92   
CATH (Classification of proteins structures)4B90    4B91    4B92   
SuperfamilyQ9BPU6
Human Protein AtlasENSG00000157851
Peptide AtlasQ9BPU6
HPRD10522
IPIIPI00335509   IPI00894526   IPI00894420   IPI00894120   
Protein Interaction databases
DIP (DOE-UCLA)Q9BPU6
IntAct (EBI)Q9BPU6
FunCoupENSG00000157851
BioGRIDDPYSL5
STRING (EMBL)DPYSL5
ZODIACDPYSL5
Ontologies - Pathways
QuickGOQ9BPU6
Ontology : AmiGOprotein binding  cytosol  signal transduction  nervous system development  axon guidance  microtubule binding  metabolic process  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds  dendrite  neuronal cell body  
Ontology : EGO-EBIprotein binding  cytosol  signal transduction  nervous system development  axon guidance  microtubule binding  metabolic process  hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds  dendrite  neuronal cell body  
Pathways : KEGGAxon guidance   
NDEx NetworkDPYSL5
Atlas of Cancer Signalling NetworkDPYSL5
Wikipedia pathwaysDPYSL5
Orthology - Evolution
OrthoDB56896
GeneTree (enSembl)ENSG00000157851
Phylogenetic Trees/Animal Genes : TreeFamDPYSL5
HOVERGENQ9BPU6
HOGENOMQ9BPU6
Homologs : HomoloGeneDPYSL5
Homology/Alignments : Family Browser (UCSC)DPYSL5
Gene fusions - Rearrangements
Fusion : MitelmanBRE/DPYSL5 [2p23.2/2p23.3]  [t(2;2)(p23;p23)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDPYSL5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DPYSL5
dbVarDPYSL5
ClinVarDPYSL5
1000_GenomesDPYSL5 
Exome Variant ServerDPYSL5
ExAC (Exome Aggregation Consortium)DPYSL5 (select the gene name)
Genetic variants : HAPMAP56896
Genomic Variants (DGV)DPYSL5 [DGVbeta]
DECIPHER (Syndromes)2:27071157-27173219  ENSG00000157851
CONAN: Copy Number AnalysisDPYSL5 
Mutations
ICGC Data PortalDPYSL5 
TCGA Data PortalDPYSL5 
Broad Tumor PortalDPYSL5
OASIS PortalDPYSL5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDPYSL5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDPYSL5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DPYSL5
DgiDB (Drug Gene Interaction Database)DPYSL5
DoCM (Curated mutations)DPYSL5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DPYSL5 (select a term)
intoGenDPYSL5
Cancer3DDPYSL5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608383   
Orphanet
MedgenDPYSL5
Genetic Testing Registry DPYSL5
NextProtQ9BPU6 [Medical]
TSGene56896
GENETestsDPYSL5
Huge Navigator DPYSL5 [HugePedia]
snp3D : Map Gene to Disease56896
BioCentury BCIQDPYSL5
ClinGenDPYSL5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD56896
Chemical/Pharm GKB GenePA134927413
Clinical trialDPYSL5
Miscellaneous
canSAR (ICR)DPYSL5 (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDPYSL5
EVEXDPYSL5
GoPubMedDPYSL5
iHOPDPYSL5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:03:50 CET 2017

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