Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DSC3 (desmocollin 3)

Identity

Alias_namesDSC4
Alias_symbol (synonym)CDHF3
DSC
DSC1
DSC2
Other aliasHT-CP
HGNC (Hugo) DSC3
LocusID (NCBI) 1825
Atlas_Id 40364
Location 18q12.1  [Link to chromosome band 18q12]
Location_base_pair Starts at 28569331 and ends at 28622781 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
MIR100HG (11q24.1) / DSC3 (18q12.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DSC3   3037
Cards
Entrez_Gene (NCBI)DSC3  1825  desmocollin 3
AliasesCDHF3; DSC; DSC1; DSC2; 
DSC4; HT-CP
GeneCards (Weizmann)DSC3
Ensembl hg19 (Hinxton)ENSG00000134762 [Gene_View]  chr18:28569331-28622781 [Contig_View]  DSC3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000134762 [Gene_View]  chr18:28569331-28622781 [Contig_View]  DSC3 [Vega]
ICGC DataPortalENSG00000134762
TCGA cBioPortalDSC3
AceView (NCBI)DSC3
Genatlas (Paris)DSC3
WikiGenes1825
SOURCE (Princeton)DSC3
Genetics Home Reference (NIH)DSC3
Genomic and cartography
GoldenPath hg19 (UCSC)DSC3  -     chr18:28569331-28622781 -  18q12.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DSC3  -     18q12.1   [Description]    (hg38-Dec_2013)
EnsemblDSC3 - 18q12.1 [CytoView hg19]  DSC3 - 18q12.1 [CytoView hg38]
Mapping of homologs : NCBIDSC3 [Mapview hg19]  DSC3 [Mapview hg38]
OMIM600271   
Gene and transcription
Genbank (Entrez)AF297090 AI123917 AK001100 AK074475 AK291748
RefSeq transcript (Entrez)NM_001941 NM_024423
RefSeq genomic (Entrez)NC_000018 NC_018929 NG_016782 NT_010966 NW_004929410
Consensus coding sequences : CCDS (NCBI)DSC3
Cluster EST : UnigeneHs.41690 [ NCBI ]
CGAP (NCI)Hs.41690
Alternative Splicing GalleryENSG00000134762
Gene ExpressionDSC3 [ NCBI-GEO ]   DSC3 [ EBI - ARRAY_EXPRESS ]   DSC3 [ SEEK ]   DSC3 [ MEM ]
Gene Expression Viewer (FireBrowse)DSC3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1825
GTEX Portal (Tissue expression)DSC3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14574   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14574  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14574
Splice isoforms : SwissVarQ14574
PhosPhoSitePlusQ14574
Domaine pattern : Prosite (Expaxy)CADHERIN_1 (PS00232)    CADHERIN_2 (PS50268)   
Domains : Interpro (EBI)Cadherin    Cadherin-like    Cadherin_CS    Cadherin_cytoplasmic-dom    Cadherin_pro_dom    Catenin_binding_dom    Desmosomal_cadherin   
Domain families : Pfam (Sanger)Cadherin (PF00028)    Cadherin_C (PF01049)    Cadherin_pro (PF08758)   
Domain families : Pfam (NCBI)pfam00028    pfam01049    pfam08758   
Domain families : Smart (EMBL)CA (SM00112)  Cadherin_pro (SM01055)  
Conserved Domain (NCBI)DSC3
DMDM Disease mutations1825
Blocks (Seattle)DSC3
SuperfamilyQ14574
Human Protein AtlasENSG00000134762
Peptide AtlasQ14574
HPRD02604
IPIIPI00031549   IPI00218928   
Protein Interaction databases
DIP (DOE-UCLA)Q14574
IntAct (EBI)Q14574
FunCoupENSG00000134762
BioGRIDDSC3
STRING (EMBL)DSC3
ZODIACDSC3
Ontologies - Pathways
QuickGOQ14574
Ontology : AmiGOcalcium ion binding  plasma membrane  cell-cell junction  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  membrane  integral component of membrane  desmosome  gamma-catenin binding  protein stabilization  
Ontology : EGO-EBIcalcium ion binding  plasma membrane  cell-cell junction  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  membrane  integral component of membrane  desmosome  gamma-catenin binding  protein stabilization  
NDEx NetworkDSC3
Atlas of Cancer Signalling NetworkDSC3
Wikipedia pathwaysDSC3
Orthology - Evolution
OrthoDB1825
GeneTree (enSembl)ENSG00000134762
Phylogenetic Trees/Animal Genes : TreeFamDSC3
HOVERGENQ14574
HOGENOMQ14574
Homologs : HomoloGeneDSC3
Homology/Alignments : Family Browser (UCSC)DSC3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDSC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DSC3
dbVarDSC3
ClinVarDSC3
1000_GenomesDSC3 
Exome Variant ServerDSC3
ExAC (Exome Aggregation Consortium)DSC3 (select the gene name)
Genetic variants : HAPMAP1825
Genomic Variants (DGV)DSC3 [DGVbeta]
DECIPHER (Syndromes)18:28569331-28622781  ENSG00000134762
CONAN: Copy Number AnalysisDSC3 
Mutations
ICGC Data PortalDSC3 
TCGA Data PortalDSC3 
Broad Tumor PortalDSC3
OASIS PortalDSC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDSC3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDSC3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DSC3
DgiDB (Drug Gene Interaction Database)DSC3
DoCM (Curated mutations)DSC3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DSC3 (select a term)
intoGenDSC3
Cancer3DDSC3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600271   
Orphanet18856   
MedgenDSC3
Genetic Testing Registry DSC3
NextProtQ14574 [Medical]
TSGene1825
GENETestsDSC3
Huge Navigator DSC3 [HugePedia]
snp3D : Map Gene to Disease1825
BioCentury BCIQDSC3
ClinGenDSC3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1825
Chemical/Pharm GKB GenePA164741482
Clinical trialDSC3
Miscellaneous
canSAR (ICR)DSC3 (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDSC3
EVEXDSC3
GoPubMedDSC3
iHOPDSC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:03:53 CET 2017

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