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DTX1 (deltex 1)

Identity

Alias_namesdeltex homolog 1 (Drosophila)
Alias_symbol (synonym)hDx-1
Other alias
HGNC (Hugo) DTX1
LocusID (NCBI) 1840
Atlas_Id 40370
Location 12q24.13  [Link to chromosome band 12q24]
Location_base_pair Starts at 113495662 and ends at 113535833 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CHD4 (12p13.31) / DTX1 (12q24.13)CHD4 12p13.31 / DTX1 12q24.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DTX1   3060
Cards
Entrez_Gene (NCBI)DTX1  1840  deltex 1
AliaseshDx-1
GeneCards (Weizmann)DTX1
Ensembl hg19 (Hinxton)ENSG00000135144 [Gene_View]  chr12:113495662-113535833 [Contig_View]  DTX1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000135144 [Gene_View]  chr12:113495662-113535833 [Contig_View]  DTX1 [Vega]
ICGC DataPortalENSG00000135144
TCGA cBioPortalDTX1
AceView (NCBI)DTX1
Genatlas (Paris)DTX1
WikiGenes1840
SOURCE (Princeton)DTX1
Genetics Home Reference (NIH)DTX1
Genomic and cartography
GoldenPath hg19 (UCSC)DTX1  -     chr12:113495662-113535833 +  12q24.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DTX1  -     12q24.13   [Description]    (hg38-Dec_2013)
EnsemblDTX1 - 12q24.13 [CytoView hg19]  DTX1 - 12q24.13 [CytoView hg38]
Mapping of homologs : NCBIDTX1 [Mapview hg19]  DTX1 [Mapview hg38]
OMIM602582   
Gene and transcription
Genbank (Entrez)AF053700 BC005816 BC008321 BC048216
RefSeq transcript (Entrez)NM_004416
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_029419 NW_004929385
Consensus coding sequences : CCDS (NCBI)DTX1
Cluster EST : UnigeneHs.372152 [ NCBI ]
CGAP (NCI)Hs.372152
Alternative Splicing GalleryENSG00000135144
Gene ExpressionDTX1 [ NCBI-GEO ]   DTX1 [ EBI - ARRAY_EXPRESS ]   DTX1 [ SEEK ]   DTX1 [ MEM ]
Gene Expression Viewer (FireBrowse)DTX1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1840
GTEX Portal (Tissue expression)DTX1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86Y01   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86Y01  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86Y01
Splice isoforms : SwissVarQ86Y01
Catalytic activity : Enzyme6.3.2.- [ Enzyme-Expasy ]   6.3.2.-6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   
PhosPhoSitePlusQ86Y01
Domaine pattern : Prosite (Expaxy)WWE (PS50918)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)WWE-dom    WWE-dom_subgr    Znf_C3HC4_RING-type    Znf_RING    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)WWE (PF02825)    zf-C3HC4 (PF00097)   
Domain families : Pfam (NCBI)pfam02825    pfam00097   
Domain families : Smart (EMBL)RING (SM00184)  WWE (SM00678)  
Conserved Domain (NCBI)DTX1
DMDM Disease mutations1840
Blocks (Seattle)DTX1
SuperfamilyQ86Y01
Human Protein AtlasENSG00000135144
Peptide AtlasQ86Y01
HPRD03991
IPIIPI00004554   
Protein Interaction databases
DIP (DOE-UCLA)Q86Y01
IntAct (EBI)Q86Y01
FunCoupENSG00000135144
BioGRIDDTX1
STRING (EMBL)DTX1
ZODIACDTX1
Ontologies - Pathways
QuickGOQ86Y01
Ontology : AmiGOtranscription coactivator activity  Notch binding  protein binding  nucleus  cytoplasm  cytosol  transcription, DNA-templated  transcription from RNA polymerase II promoter  cell surface receptor signaling pathway  Notch signaling pathway  zinc ion binding  regulation of Notch signaling pathway  glial cell differentiation  protein ubiquitination  ligase activity  SH3 domain binding  ubiquitin protein ligase binding  negative regulation of T cell differentiation  negative regulation of neuron differentiation  regulation of nucleic acid-templated transcription  
Ontology : EGO-EBItranscription coactivator activity  Notch binding  protein binding  nucleus  cytoplasm  cytosol  transcription, DNA-templated  transcription from RNA polymerase II promoter  cell surface receptor signaling pathway  Notch signaling pathway  zinc ion binding  regulation of Notch signaling pathway  glial cell differentiation  protein ubiquitination  ligase activity  SH3 domain binding  ubiquitin protein ligase binding  negative regulation of T cell differentiation  negative regulation of neuron differentiation  regulation of nucleic acid-templated transcription  
Pathways : KEGGNotch signaling pathway   
NDEx NetworkDTX1
Atlas of Cancer Signalling NetworkDTX1
Wikipedia pathwaysDTX1
Orthology - Evolution
OrthoDB1840
GeneTree (enSembl)ENSG00000135144
Phylogenetic Trees/Animal Genes : TreeFamDTX1
HOVERGENQ86Y01
HOGENOMQ86Y01
Homologs : HomoloGeneDTX1
Homology/Alignments : Family Browser (UCSC)DTX1
Gene fusions - Rearrangements
Fusion : MitelmanCHD4/DTX1 [12p13.31/12q24.13]  [t(12;12)(p13;q24)]  
Fusion: TCGACHD4 12p13.31 DTX1 12q24.13 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDTX1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DTX1
dbVarDTX1
ClinVarDTX1
1000_GenomesDTX1 
Exome Variant ServerDTX1
ExAC (Exome Aggregation Consortium)DTX1 (select the gene name)
Genetic variants : HAPMAP1840
Genomic Variants (DGV)DTX1 [DGVbeta]
DECIPHER (Syndromes)12:113495662-113535833  ENSG00000135144
CONAN: Copy Number AnalysisDTX1 
Mutations
ICGC Data PortalDTX1 
TCGA Data PortalDTX1 
Broad Tumor PortalDTX1
OASIS PortalDTX1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDTX1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDTX1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DTX1
DgiDB (Drug Gene Interaction Database)DTX1
DoCM (Curated mutations)DTX1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DTX1 (select a term)
intoGenDTX1
Cancer3DDTX1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602582   
Orphanet
MedgenDTX1
Genetic Testing Registry DTX1
NextProtQ86Y01 [Medical]
TSGene1840
GENETestsDTX1
Huge Navigator DTX1 [HugePedia]
snp3D : Map Gene to Disease1840
BioCentury BCIQDTX1
ClinGenDTX1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1840
Chemical/Pharm GKB GenePA27514
Clinical trialDTX1
Miscellaneous
canSAR (ICR)DTX1 (select the gene name)
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDTX1
EVEXDTX1
GoPubMedDTX1
iHOPDTX1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:03:57 CET 2017

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