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EBI3 (Epstein-Barr virus induced 3)

Identity

Alias_symbol (synonym)IL27B
IL35B
Other aliasIL-27B
HGNC (Hugo) EBI3
LocusID (NCBI) 10148
Atlas_Id 52627
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 4229540 and ends at 4237524 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
EBI3 (19p13.3) / PPP6R1 (19q13.42)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)EBI3   3129
Cards
Entrez_Gene (NCBI)EBI3  10148  Epstein-Barr virus induced 3
AliasesIL-27B; IL27B
GeneCards (Weizmann)EBI3
Ensembl hg19 (Hinxton)ENSG00000105246 [Gene_View]  chr19:4229540-4237524 [Contig_View]  EBI3 [Vega]
Ensembl hg38 (Hinxton)ENSG00000105246 [Gene_View]  chr19:4229540-4237524 [Contig_View]  EBI3 [Vega]
ICGC DataPortalENSG00000105246
TCGA cBioPortalEBI3
AceView (NCBI)EBI3
Genatlas (Paris)EBI3
WikiGenes10148
SOURCE (Princeton)EBI3
Genetics Home Reference (NIH)EBI3
Genomic and cartography
GoldenPath hg19 (UCSC)EBI3  -     chr19:4229540-4237524 +  19p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)EBI3  -     19p13.3   [Description]    (hg38-Dec_2013)
EnsemblEBI3 - 19p13.3 [CytoView hg19]  EBI3 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIEBI3 [Mapview hg19]  EBI3 [Mapview hg38]
OMIM605816   
Gene and transcription
Genbank (Entrez)BC015364 BC046112 DQ891589 EU176581 L08187
RefSeq transcript (Entrez)NM_005755
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929412
Consensus coding sequences : CCDS (NCBI)EBI3
Cluster EST : UnigeneHs.501452 [ NCBI ]
CGAP (NCI)Hs.501452
Alternative Splicing GalleryENSG00000105246
Gene ExpressionEBI3 [ NCBI-GEO ]   EBI3 [ EBI - ARRAY_EXPRESS ]   EBI3 [ SEEK ]   EBI3 [ MEM ]
Gene Expression Viewer (FireBrowse)EBI3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10148
GTEX Portal (Tissue expression)EBI3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14213   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14213  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14213
Splice isoforms : SwissVarQ14213
PhosPhoSitePlusQ14213
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    HEMATOPO_REC_L_F3 (PS01354)   
Domains : Interpro (EBI)FN3_dom    Hematopoietin_rcpt_L_F3_CS    Ig-like_fold   
Domain families : Pfam (Sanger)fn3 (PF00041)   
Domain families : Pfam (NCBI)pfam00041   
Domain families : Smart (EMBL)FN3 (SM00060)  
Conserved Domain (NCBI)EBI3
DMDM Disease mutations10148
Blocks (Seattle)EBI3
SuperfamilyQ14213
Human Protein AtlasENSG00000105246
Peptide AtlasQ14213
HPRD12051
IPIIPI00034088   
Protein Interaction databases
DIP (DOE-UCLA)Q14213
IntAct (EBI)Q14213
FunCoupENSG00000105246
BioGRIDEBI3
STRING (EMBL)EBI3
ZODIACEBI3
Ontologies - Pathways
QuickGOQ14213
Ontology : AmiGOcytokine receptor activity  cytokine activity  protein binding  extracellular region  extracellular space  plasma membrane  humoral immune response  cytokine-mediated signaling pathway  cytokine-mediated signaling pathway  T-helper 1 type immune response  T cell proliferation  positive regulation of interferon-gamma biosynthetic process  interleukin-27 receptor binding  positive regulation of alpha-beta T cell proliferation  
Ontology : EGO-EBIcytokine receptor activity  cytokine activity  protein binding  extracellular region  extracellular space  plasma membrane  humoral immune response  cytokine-mediated signaling pathway  cytokine-mediated signaling pathway  T-helper 1 type immune response  T cell proliferation  positive regulation of interferon-gamma biosynthetic process  interleukin-27 receptor binding  positive regulation of alpha-beta T cell proliferation  
NDEx NetworkEBI3
Atlas of Cancer Signalling NetworkEBI3
Wikipedia pathwaysEBI3
Orthology - Evolution
OrthoDB10148
GeneTree (enSembl)ENSG00000105246
Phylogenetic Trees/Animal Genes : TreeFamEBI3
HOVERGENQ14213
HOGENOMQ14213
Homologs : HomoloGeneEBI3
Homology/Alignments : Family Browser (UCSC)EBI3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerEBI3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)EBI3
dbVarEBI3
ClinVarEBI3
1000_GenomesEBI3 
Exome Variant ServerEBI3
ExAC (Exome Aggregation Consortium)EBI3 (select the gene name)
Genetic variants : HAPMAP10148
Genomic Variants (DGV)EBI3 [DGVbeta]
DECIPHER (Syndromes)19:4229540-4237524  ENSG00000105246
CONAN: Copy Number AnalysisEBI3 
Mutations
ICGC Data PortalEBI3 
TCGA Data PortalEBI3 
Broad Tumor PortalEBI3
OASIS PortalEBI3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICEBI3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDEBI3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch EBI3
DgiDB (Drug Gene Interaction Database)EBI3
DoCM (Curated mutations)EBI3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)EBI3 (select a term)
intoGenEBI3
Cancer3DEBI3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605816   
Orphanet
MedgenEBI3
Genetic Testing Registry EBI3
NextProtQ14213 [Medical]
TSGene10148
GENETestsEBI3
Huge Navigator EBI3 [HugePedia]
snp3D : Map Gene to Disease10148
BioCentury BCIQEBI3
ClinGenEBI3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10148
Chemical/Pharm GKB GenePA27584
Clinical trialEBI3
Miscellaneous
canSAR (ICR)EBI3 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineEBI3
EVEXEBI3
GoPubMedEBI3
iHOPEBI3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Thu Mar 30 14:59:38 CEST 2017

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