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EN1 (engrailed homeobox 1)

Identity

Other names-
HGNC (Hugo) EN1
LocusID (NCBI) 2019
Location 2q14.2
Location_base_pair Starts at 119599747 and ends at 119605759 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)EN1   3342
Entrez_Gene (NCBI)EN1  2019  engrailed homeobox 1
Cards
GeneCards (Weizmann)EN1
Ensembl (Hinxton)ENSG00000163064 [Gene_View]  chr2:119599747-119605759 [Contig_View]  EN1 [Vega]
AceView (NCBI)EN1
Genatlas (Paris)EN1
SOURCE (Stanford)NM_001426
Genomic and cartography
GoldenPath (UCSC)EN1  -  2q14.2   chr2:119599747-119605759 -  2q14.2   [Description]    (hg19-Feb_2009)
EnsemblEN1 - 2q14.2 [CytoView]
Mapping of homologs : NCBIEN1 [Mapview]
OMIM131290   
Gene and transcription
Genbank (Entrez)BC111840
RefSeq transcript (SRS)NM_001426
RefSeq transcript (Entrez)NM_001426
RefSeq genomic (SRS)AC_000134 NC_000002 NC_018913 NG_007123 NT_022135 NW_001838847 NW_004078008
RefSeq genomic (Entrez)AC_000134 NC_000002 NC_018913 NG_007123 NT_022135 NW_001838847 NW_004078008
Consensus coding sequences : CCDS (NCBI)EN1
Cluster EST : UnigeneHs.271977 [ SRS ] Hs.271977 [ NCBI ]
CGAP (NCI)Hs.271977
Alternative Splicing : Fast-db (Paris)GSHG0017950
Alternative Splicing GalleryENSG00000163064
Gene ExpressionEN1 [ NCBI-GEO ]   EN1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ05925 (SRS) Q05925 (Uniprot)
NextProtQ05925
With graphics : InterProQ05925
Splice isoforms : SwissVarQ05925(Swissvar)
Domaine pattern : Prosite (SRS)ENGRAILED (PS00033)    HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domaine pattern : Prosite (Expaxy)ENGRAILED (PS00033)    HOMEOBOX_1 (PS00027)    HOMEOBOX_2 (PS50071)   
Domains : Interpro (SRS)Homeobox-engrailed_C-terminal    Homeobox_CS    Homeobox_metazoa    Homeodomain    Homeodomain-like    Homeodomain_engrailed    Homoebox-engrailed_CS   
Domains : Interpro (EBI)Homeobox-engrailed_C-terminal    Homeobox_CS    Homeobox_metazoa    Homeodomain    Homeodomain-like    Homeodomain_engrailed    Homoebox-engrailed_CS   
Related proteins : CluSTrQ05925
Domain families : Pfam (SRS)Engrail_1_C_sig (PF10525)    Homeobox (PF00046)   
Domain families : Pfam (Sanger)Engrail_1_C_sig (PF10525)    Homeobox (PF00046)   
Domain families : Pfam (NCBI)pfam10525    pfam00046   
Domain families : Smart (EMBL)HOX (SM00389)  
DMDM2019
Blocks (Seattle)Q05925
Human Protein AtlasENSG00000163064
HPRD08835
IPIIPI00016734   
Protein Interaction databases
DIP (DOE-UCLA)Q05925
IntAct (EBI)Q05925
FunCoupENSG00000163064
REACTOMEEN1
Protein Interaction Database2019
BioGRIDEN1
InParanoidQ05925
Interologous Interaction database Q05925
IntegromeDBEN1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)EN1
SNP (GeneSNP Utah)EN1
SNP : HGBaseEN1
Genetic variants : HAPMAPEN1
Somatic Mutations in Cancer : COSMICEN1 
CONAN: Copy Number AnalysisEN1 
Mutations and Diseases : HGMDEN1
OMIM131290   
GENETests131290   
Disease Genetic AssociationEN1
Huge Navigator EN1 [HugePedia]  EN1 [HugeCancerGEM]
Genomic VariantsEN1  EN1 [DGVbeta]
ClinVarEN1
snp3D : Map Gene to Disease2019
General knowledge
Homologs : HomoloGeneEN1
Homology/Alignments : Family Browser (UCSC)EN1
Phylogenetic Trees/Animal Genes : TreeFamEN1
Chemical/Protein Interactions : CTD2019
Chemical/Pharm GKB GenePA27779
Clinical trialEN1
Cancer Resource (Charite)ENSG00000163064
Ontology : AmiGOskeletal system development  sequence-specific DNA binding transcription factor activity  nucleus  anatomical structure morphogenesis  dorsal/ventral pattern formation  proximal/distal pattern formation  midbrain development  hindbrain development  midbrain-hindbrain boundary development  embryonic forelimb morphogenesis  pigmentation  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  neuron development  
Ontology : EGO-EBIskeletal system development  sequence-specific DNA binding transcription factor activity  nucleus  anatomical structure morphogenesis  dorsal/ventral pattern formation  proximal/distal pattern formation  midbrain development  hindbrain development  midbrain-hindbrain boundary development  embryonic forelimb morphogenesis  pigmentation  sequence-specific DNA binding  positive regulation of transcription from RNA polymerase II promoter  neuron development  
Other databases
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
PubGeneEN1
iHOPEN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 14 17:53:15 CEST 2013
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