Atlas of Genetics and Cytogenetics in Oncology and Haematology


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ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5)

Identity

Alias_namesCD39L4
PCPH
proto-oncogene CPH
Alias_symbol (synonym)NTPDase-5
Other alias
HGNC (Hugo) ENTPD5
LocusID (NCBI) 957
Atlas_Id 45704
Location 14q24.3  [Link to chromosome band 14q24]
Location_base_pair Starts at 73963231 and ends at 74019323 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ENTPD5 (14q24.3) / ENTPD5 (14q24.3)ENTPD5 (14q24.3) / TCTN3 (10q24.1)MARK3 (14q32.32) / ENTPD5 (14q24.3)
MARK3 14q32.32 / ENTPD5 14q24.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ENTPD5   3367
Cards
Entrez_Gene (NCBI)ENTPD5  957  ectonucleoside triphosphate diphosphohydrolase 5
AliasesCD39L4; NTPDase-5; PCPH
GeneCards (Weizmann)ENTPD5
Ensembl hg19 (Hinxton)ENSG00000187097 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187097 [Gene_View]  chr14:73963231-74019323 [Contig_View]  ENTPD5 [Vega]
ICGC DataPortalENSG00000187097
TCGA cBioPortalENTPD5
AceView (NCBI)ENTPD5
Genatlas (Paris)ENTPD5
WikiGenes957
SOURCE (Princeton)ENTPD5
Genetics Home Reference (NIH)ENTPD5
Genomic and cartography
GoldenPath hg38 (UCSC)ENTPD5  -     chr14:73963231-74019323 -  14q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)ENTPD5  -     14q24.3   [Description]    (hg19-Feb_2009)
EnsemblENTPD5 - 14q24.3 [CytoView hg19]  ENTPD5 - 14q24.3 [CytoView hg38]
Mapping of homologs : NCBIENTPD5 [Mapview hg19]  ENTPD5 [Mapview hg38]
OMIM603162   
Gene and transcription
Genbank (Entrez)AF039918 AF136572 AK025209 AW028387 AY430094
RefSeq transcript (Entrez)NM_001249 NM_001321984 NM_001321985 NM_001321986 NM_001321987 NM_001321988 NM_001330189
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)ENTPD5
Cluster EST : UnigeneHs.720540 [ NCBI ]
CGAP (NCI)Hs.720540
Alternative Splicing GalleryENSG00000187097
Gene ExpressionENTPD5 [ NCBI-GEO ]   ENTPD5 [ EBI - ARRAY_EXPRESS ]   ENTPD5 [ SEEK ]   ENTPD5 [ MEM ]
Gene Expression Viewer (FireBrowse)ENTPD5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)957
GTEX Portal (Tissue expression)ENTPD5
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75356   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75356  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75356
Splice isoforms : SwissVarO75356
Catalytic activity : Enzyme3.6.1.6 [ Enzyme-Expasy ]   3.6.1.63.6.1.6 [ IntEnz-EBI ]   3.6.1.6 [ BRENDA ]   3.6.1.6 [ KEGG ]   
PhosPhoSitePlusO75356
Domaine pattern : Prosite (Expaxy)GDA1_CD39_NTPASE (PS01238)   
Domains : Interpro (EBI)GDA1_CD39_NTPase   
Domain families : Pfam (Sanger)GDA1_CD39 (PF01150)   
Domain families : Pfam (NCBI)pfam01150   
Conserved Domain (NCBI)ENTPD5
DMDM Disease mutations957
Blocks (Seattle)ENTPD5
SuperfamilyO75356
Human Protein AtlasENSG00000187097
Peptide AtlasO75356
HPRD16015
IPIIPI00215952   IPI01025727   IPI01025855   IPI01026461   IPI01026586   
Protein Interaction databases
DIP (DOE-UCLA)O75356
IntAct (EBI)O75356
FunCoupENSG00000187097
BioGRIDENTPD5
STRING (EMBL)ENTPD5
ZODIACENTPD5
Ontologies - Pathways
QuickGOO75356
Ontology : AmiGOguanosine-diphosphatase activity  protein binding  extracellular region  endoplasmic reticulum  protein N-linked glycosylation  cell proliferation  regulation of phosphatidylinositol 3-kinase signaling  cell growth  nucleoside-diphosphatase activity  uridine-diphosphatase activity  positive regulation of glycolytic process  ATP metabolic process  'de novo' posttranslational protein folding  nucleobase-containing small molecule metabolic process  extracellular exosome  
Ontology : EGO-EBIguanosine-diphosphatase activity  protein binding  extracellular region  endoplasmic reticulum  protein N-linked glycosylation  cell proliferation  regulation of phosphatidylinositol 3-kinase signaling  cell growth  nucleoside-diphosphatase activity  uridine-diphosphatase activity  positive regulation of glycolytic process  ATP metabolic process  'de novo' posttranslational protein folding  nucleobase-containing small molecule metabolic process  extracellular exosome  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism   
NDEx NetworkENTPD5
Atlas of Cancer Signalling NetworkENTPD5
Wikipedia pathwaysENTPD5
Orthology - Evolution
OrthoDB957
GeneTree (enSembl)ENSG00000187097
Phylogenetic Trees/Animal Genes : TreeFamENTPD5
HOVERGENO75356
HOGENOMO75356
Homologs : HomoloGeneENTPD5
Homology/Alignments : Family Browser (UCSC)ENTPD5
Gene fusions - Rearrangements
Fusion : MitelmanMARK3/ENTPD5 [14q32.32/14q24.3]  [t(14;14)(q24;q32)]  
Fusion: TCGAMARK3 14q32.32 ENTPD5 14q24.3 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerENTPD5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ENTPD5
dbVarENTPD5
ClinVarENTPD5
1000_GenomesENTPD5 
Exome Variant ServerENTPD5
ExAC (Exome Aggregation Consortium)ENTPD5 (select the gene name)
Genetic variants : HAPMAP957
Genomic Variants (DGV)ENTPD5 [DGVbeta]
DECIPHERENTPD5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisENTPD5 
Mutations
ICGC Data PortalENTPD5 
TCGA Data PortalENTPD5 
Broad Tumor PortalENTPD5
OASIS PortalENTPD5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICENTPD5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDENTPD5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ENTPD5
DgiDB (Drug Gene Interaction Database)ENTPD5
DoCM (Curated mutations)ENTPD5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ENTPD5 (select a term)
intoGenENTPD5
Cancer3DENTPD5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603162   
Orphanet
MedgenENTPD5
Genetic Testing Registry ENTPD5
NextProtO75356 [Medical]
TSGene957
GENETestsENTPD5
Target ValidationENTPD5
Huge Navigator ENTPD5 [HugePedia]
snp3D : Map Gene to Disease957
BioCentury BCIQENTPD5
ClinGenENTPD5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD957
Chemical/Pharm GKB GenePA27802
Clinical trialENTPD5
Miscellaneous
canSAR (ICR)ENTPD5 (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineENTPD5
EVEXENTPD5
GoPubMedENTPD5
iHOPENTPD5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:32:39 CEST 2017

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