ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive))

2007-02-01  

Identity

HGNC
LOCATION
14q24.3
LOCUSID
ALIAS
CD39L4,NTPDase-5,PCPH
FUSION GENES

Other Information

Locus ID:

NCBI: 957
MIM: 603162
HGNC: 3367
Ensembl: ENSG00000187097

Variants:

dbSNP: 957
ClinVar: 957
TCGA: ENSG00000187097
COSMIC: ENTPD5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000187097ENST00000334696O75356
ENSG00000187097ENST00000334696A0A024R6D3
ENSG00000187097ENST00000553284G3V450
ENSG00000187097ENST00000555829H0YJH1
ENSG00000187097ENST00000556242G3V3Y0
ENSG00000187097ENST00000557325G3V4I0

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Purine metabolismKEGGko00230
Pyrimidine metabolismKEGGko00240
Purine metabolismKEGGhsa00230
Pyrimidine metabolismKEGGhsa00240
MetabolismREACTOMER-HSA-1430728
Metabolism of nucleotidesREACTOMER-HSA-15869
Phosphate bond hydrolysis by NTPDase proteinsREACTOMER-HSA-8850843

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
368494242023The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation.3
368494242023The UDPase ENTPD5 regulates ER stress-associated renal injury by mediating protein N-glycosylation.3
339637152021[ENTPD5 gene is highly expressed in epithelial ovarian cancer: analysis based on Oncomine database and bioinformatics].1
340755262021ENTPD5: identification of splicing variants and their impact on cancer survival.3
342726512021ENTPD5 splice variants: novel players in cancer?0
339637152021[ENTPD5 gene is highly expressed in epithelial ovarian cancer: analysis based on Oncomine database and bioinformatics].1
340755262021ENTPD5: identification of splicing variants and their impact on cancer survival.3
342726512021ENTPD5 splice variants: novel players in cancer?0
279566232016Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.55
279566232016Mutant p53 promotes tumor progression and metastasis by the endoplasmic reticulum UDPase ENTPD5.55
257940102015ENTPD5 induces apoptosis in lung cancer cells via regulating caspase 3 expression.6
257940102015ENTPD5 induces apoptosis in lung cancer cells via regulating caspase 3 expression.6
250456562014NTPDase5/PCPH as a new target in highly aggressive tumors: a systematic review.3
250456562014NTPDase5/PCPH as a new target in highly aggressive tumors: a systematic review.3
239214412013The ENTPD5/mt-PCPH oncoprotein is a catalytically inactive member of the ectonucleoside triphosphate diphosphohydrolase family.9

Citation

Dessen P

ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive))

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45704/entpd5