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FBXO45 (F-box protein 45)

Identity

Alias_symbol (synonym)Fbx45
Other alias
HGNC (Hugo) FBXO45
LocusID (NCBI) 200933
Atlas_Id 46728
Location 3q29  [Link to chromosome band 3q29]
Location_base_pair Starts at 196568854 and ends at 196589059 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NAALADL2 (3q26.31) / FBXO45 (3q29)NAALADL2 3q26.31 / FBXO45 3q29

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXO45   29148
Cards
Entrez_Gene (NCBI)FBXO45  200933  F-box protein 45
AliasesFbx45
GeneCards (Weizmann)FBXO45
Ensembl hg19 (Hinxton)ENSG00000174013 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174013 [Gene_View]  chr3:196568854-196589059 [Contig_View]  FBXO45 [Vega]
ICGC DataPortalENSG00000174013
TCGA cBioPortalFBXO45
AceView (NCBI)FBXO45
Genatlas (Paris)FBXO45
WikiGenes200933
SOURCE (Princeton)FBXO45
Genetics Home Reference (NIH)FBXO45
Genomic and cartography
GoldenPath hg38 (UCSC)FBXO45  -     chr3:196568854-196589059 +  3q29   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXO45  -     3q29   [Description]    (hg19-Feb_2009)
EnsemblFBXO45 - 3q29 [CytoView hg19]  FBXO45 - 3q29 [CytoView hg38]
Mapping of homologs : NCBIFBXO45 [Mapview hg19]  FBXO45 [Mapview hg38]
OMIM609112   
Gene and transcription
Genbank (Entrez)AK025697 BC172382 BE047625 BE778263 CA445163
RefSeq transcript (Entrez)NM_001105573
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBXO45
Cluster EST : UnigeneHs.169815 [ NCBI ]
CGAP (NCI)Hs.169815
Alternative Splicing GalleryENSG00000174013
Gene ExpressionFBXO45 [ NCBI-GEO ]   FBXO45 [ EBI - ARRAY_EXPRESS ]   FBXO45 [ SEEK ]   FBXO45 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO45 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)200933
GTEX Portal (Tissue expression)FBXO45
Protein : pattern, domain, 3D structure
UniProt/SwissProtP0C2W1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP0C2W1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP0C2W1
Splice isoforms : SwissVarP0C2W1
PhosPhoSitePlusP0C2W1
Domaine pattern : Prosite (Expaxy)B302_SPRY (PS50188)    FBOX (PS50181)   
Domains : Interpro (EBI)B30.2/SPRY    ConA-like_dom    F-box_dom    SPRY_dom   
Domain families : Pfam (Sanger)F-box-like (PF12937)    SPRY (PF00622)   
Domain families : Pfam (NCBI)pfam12937    pfam00622   
Domain families : Smart (EMBL)FBOX (SM00256)  SPRY (SM00449)  
Conserved Domain (NCBI)FBXO45
DMDM Disease mutations200933
Blocks (Seattle)FBXO45
SuperfamilyP0C2W1
Human Protein AtlasENSG00000174013
Peptide AtlasP0C2W1
IPIIPI00174438   IPI00927873   
Protein Interaction databases
DIP (DOE-UCLA)P0C2W1
IntAct (EBI)P0C2W1
FunCoupENSG00000174013
BioGRIDFBXO45
STRING (EMBL)FBXO45
ZODIACFBXO45
Ontologies - Pathways
QuickGOP0C2W1
Ontology : AmiGOneuron migration  protein binding  cellular response to DNA damage stimulus  postsynaptic density  protein ubiquitination  protein ubiquitination  cerebral cortex radially oriented cell migration  cerebral cortex tangential migration  corticospinal tract morphogenesis  anterior commissure morphogenesis  cell junction  presynaptic membrane  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  postsynaptic membrane  synapse assembly involved in innervation  
Ontology : EGO-EBIneuron migration  protein binding  cellular response to DNA damage stimulus  postsynaptic density  protein ubiquitination  protein ubiquitination  cerebral cortex radially oriented cell migration  cerebral cortex tangential migration  corticospinal tract morphogenesis  anterior commissure morphogenesis  cell junction  presynaptic membrane  protein ubiquitination involved in ubiquitin-dependent protein catabolic process  proteasome-mediated ubiquitin-dependent protein catabolic process  postsynaptic membrane  synapse assembly involved in innervation  
NDEx NetworkFBXO45
Atlas of Cancer Signalling NetworkFBXO45
Wikipedia pathwaysFBXO45
Orthology - Evolution
OrthoDB200933
GeneTree (enSembl)ENSG00000174013
Phylogenetic Trees/Animal Genes : TreeFamFBXO45
HOVERGENP0C2W1
HOGENOMP0C2W1
Homologs : HomoloGeneFBXO45
Homology/Alignments : Family Browser (UCSC)FBXO45
Gene fusions - Rearrangements
Fusion : MitelmanNAALADL2/FBXO45 [3q26.31/3q29]  [t(3;3)(q26;q29)]  
Fusion: TCGANAALADL2 3q26.31 FBXO45 3q29 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO45 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO45
dbVarFBXO45
ClinVarFBXO45
1000_GenomesFBXO45 
Exome Variant ServerFBXO45
ExAC (Exome Aggregation Consortium)FBXO45 (select the gene name)
Genetic variants : HAPMAP200933
Genomic Variants (DGV)FBXO45 [DGVbeta]
DECIPHERFBXO45 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXO45 
Mutations
ICGC Data PortalFBXO45 
TCGA Data PortalFBXO45 
Broad Tumor PortalFBXO45
OASIS PortalFBXO45 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO45  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXO45
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXO45
DgiDB (Drug Gene Interaction Database)FBXO45
DoCM (Curated mutations)FBXO45 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXO45 (select a term)
intoGenFBXO45
Cancer3DFBXO45(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609112   
Orphanet
MedgenFBXO45
Genetic Testing Registry FBXO45
NextProtP0C2W1 [Medical]
TSGene200933
GENETestsFBXO45
Target ValidationFBXO45
Huge Navigator FBXO45 [HugePedia]
snp3D : Map Gene to Disease200933
BioCentury BCIQFBXO45
ClinGenFBXO45
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD200933
Chemical/Pharm GKB GenePA134904114
Clinical trialFBXO45
Miscellaneous
canSAR (ICR)FBXO45 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXO45
EVEXFBXO45
GoPubMedFBXO45
iHOPFBXO45
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:01:04 CEST 2017

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