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FBXO6 (F-box protein 6)

Identity

Alias_namesF-box only protein 6
Alias_symbol (synonym)FBX6
FBG2
FBS2
Fbx6b
Other alias
HGNC (Hugo) FBXO6
LocusID (NCBI) 26270
Atlas_Id 46885
Location 1p36.22  [Link to chromosome band 1p36]
Location_base_pair Starts at 11664093 and ends at 11674352 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FBXO6 (1p36.22) / GPR108 (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXO6   13585
Cards
Entrez_Gene (NCBI)FBXO6  26270  F-box protein 6
AliasesFBG2; FBS2; FBX6; Fbx6b
GeneCards (Weizmann)FBXO6
Ensembl hg19 (Hinxton)ENSG00000116663 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000116663 [Gene_View]  chr1:11664093-11674352 [Contig_View]  FBXO6 [Vega]
ICGC DataPortalENSG00000116663
TCGA cBioPortalFBXO6
AceView (NCBI)FBXO6
Genatlas (Paris)FBXO6
WikiGenes26270
SOURCE (Princeton)FBXO6
Genetics Home Reference (NIH)FBXO6
Genomic and cartography
GoldenPath hg38 (UCSC)FBXO6  -     chr1:11664093-11674352 +  1p36.22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FBXO6  -     1p36.22   [Description]    (hg19-Feb_2009)
EnsemblFBXO6 - 1p36.22 [CytoView hg19]  FBXO6 - 1p36.22 [CytoView hg38]
Mapping of homologs : NCBIFBXO6 [Mapview hg19]  FBXO6 [Mapview hg38]
OMIM605647   
Gene and transcription
Genbank (Entrez)AF129536 AF233223 AK314989 BC020880 HQ447671
RefSeq transcript (Entrez)NM_018438
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FBXO6
Cluster EST : UnigeneHs.464419 [ NCBI ]
CGAP (NCI)Hs.464419
Alternative Splicing GalleryENSG00000116663
Gene ExpressionFBXO6 [ NCBI-GEO ]   FBXO6 [ EBI - ARRAY_EXPRESS ]   FBXO6 [ SEEK ]   FBXO6 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26270
GTEX Portal (Tissue expression)FBXO6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRD1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRD1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRD1
Splice isoforms : SwissVarQ9NRD1
PhosPhoSitePlusQ9NRD1
Domaine pattern : Prosite (Expaxy)FBA (PS51114)    FBOX (PS50181)   
Domains : Interpro (EBI)F-box-assoc_dom    F-box_dom    Galactose-bd-like   
Domain families : Pfam (Sanger)F-box-like (PF12937)    FBA (PF04300)   
Domain families : Pfam (NCBI)pfam12937    pfam04300   
Domain families : Smart (EMBL)FBA (SM01198)  FBOX (SM00256)  
Conserved Domain (NCBI)FBXO6
DMDM Disease mutations26270
Blocks (Seattle)FBXO6
SuperfamilyQ9NRD1
Human Protein AtlasENSG00000116663
Peptide AtlasQ9NRD1
HPRD07291
IPIIPI00171291   IPI00514344   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRD1
IntAct (EBI)Q9NRD1
FunCoupENSG00000116663
BioGRIDFBXO6
STRING (EMBL)FBXO6
ZODIACFBXO6
Ontologies - Pathways
QuickGOQ9NRD1
Ontology : AmiGODNA damage checkpoint  protein polyubiquitination  glycoprotein binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  DNA repair  proteolysis  glycoprotein catabolic process  response to unfolded protein  SCF ubiquitin ligase complex  carbohydrate binding  ubiquitin-dependent ERAD pathway  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  endoplasmic reticulum quality control compartment  ubiquitin protein ligase activity  
Ontology : EGO-EBIDNA damage checkpoint  protein polyubiquitination  glycoprotein binding  ubiquitin-protein transferase activity  ubiquitin-protein transferase activity  protein binding  cytoplasm  cytosol  DNA repair  proteolysis  glycoprotein catabolic process  response to unfolded protein  SCF ubiquitin ligase complex  carbohydrate binding  ubiquitin-dependent ERAD pathway  SCF-dependent proteasomal ubiquitin-dependent protein catabolic process  endoplasmic reticulum quality control compartment  ubiquitin protein ligase activity  
Pathways : KEGGProtein processing in endoplasmic reticulum   
NDEx NetworkFBXO6
Atlas of Cancer Signalling NetworkFBXO6
Wikipedia pathwaysFBXO6
Orthology - Evolution
OrthoDB26270
GeneTree (enSembl)ENSG00000116663
Phylogenetic Trees/Animal Genes : TreeFamFBXO6
HOVERGENQ9NRD1
HOGENOMQ9NRD1
Homologs : HomoloGeneFBXO6
Homology/Alignments : Family Browser (UCSC)FBXO6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO6
dbVarFBXO6
ClinVarFBXO6
1000_GenomesFBXO6 
Exome Variant ServerFBXO6
ExAC (Exome Aggregation Consortium)FBXO6 (select the gene name)
Genetic variants : HAPMAP26270
Genomic Variants (DGV)FBXO6 [DGVbeta]
DECIPHERFBXO6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFBXO6 
Mutations
ICGC Data PortalFBXO6 
TCGA Data PortalFBXO6 
Broad Tumor PortalFBXO6
OASIS PortalFBXO6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXO6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXO6
DgiDB (Drug Gene Interaction Database)FBXO6
DoCM (Curated mutations)FBXO6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXO6 (select a term)
intoGenFBXO6
Cancer3DFBXO6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605647   
Orphanet
MedgenFBXO6
Genetic Testing Registry FBXO6
NextProtQ9NRD1 [Medical]
TSGene26270
GENETestsFBXO6
Target ValidationFBXO6
Huge Navigator FBXO6 [HugePedia]
snp3D : Map Gene to Disease26270
BioCentury BCIQFBXO6
ClinGenFBXO6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26270
Chemical/Pharm GKB GenePA28046
Clinical trialFBXO6
Miscellaneous
canSAR (ICR)FBXO6 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXO6
EVEXFBXO6
GoPubMedFBXO6
iHOPFBXO6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:53:16 CEST 2017

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