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FBXO8 (F-box protein 8)

Identity

Alias_namesF-box only protein 8
Alias_symbol (synonym)FBX8
FBS
Other aliasDC10
HGNC (Hugo) FBXO8
LocusID (NCBI) 26269
Atlas_Id 43256
Location 4q34.1  [Link to chromosome band 4q34]
Location_base_pair Starts at 175157810 and ends at 175205402 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FBXO8   13587
Cards
Entrez_Gene (NCBI)FBXO8  26269  F-box protein 8
AliasesDC10; FBS; FBX8
GeneCards (Weizmann)FBXO8
Ensembl hg19 (Hinxton)ENSG00000164117 [Gene_View]  chr4:175157810-175205402 [Contig_View]  FBXO8 [Vega]
Ensembl hg38 (Hinxton)ENSG00000164117 [Gene_View]  chr4:175157810-175205402 [Contig_View]  FBXO8 [Vega]
ICGC DataPortalENSG00000164117
TCGA cBioPortalFBXO8
AceView (NCBI)FBXO8
Genatlas (Paris)FBXO8
WikiGenes26269
SOURCE (Princeton)FBXO8
Genetics Home Reference (NIH)FBXO8
Genomic and cartography
GoldenPath hg19 (UCSC)FBXO8  -     chr4:175157810-175205402 -  4q34.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)FBXO8  -     4q34.1   [Description]    (hg38-Dec_2013)
EnsemblFBXO8 - 4q34.1 [CytoView hg19]  FBXO8 - 4q34.1 [CytoView hg38]
Mapping of homologs : NCBIFBXO8 [Mapview hg19]  FBXO8 [Mapview hg38]
OMIM605649   
Gene and transcription
Genbank (Entrez)AF115514 AF174596 AF201932 AF233224 AK026319
RefSeq transcript (Entrez)NM_012180
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)FBXO8
Cluster EST : UnigeneHs.76917 [ NCBI ]
CGAP (NCI)Hs.76917
Alternative Splicing GalleryENSG00000164117
Gene ExpressionFBXO8 [ NCBI-GEO ]   FBXO8 [ EBI - ARRAY_EXPRESS ]   FBXO8 [ SEEK ]   FBXO8 [ MEM ]
Gene Expression Viewer (FireBrowse)FBXO8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26269
GTEX Portal (Tissue expression)FBXO8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRD0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NRD0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NRD0
Splice isoforms : SwissVarQ9NRD0
PhosPhoSitePlusQ9NRD0
Domaine pattern : Prosite (Expaxy)FBOX (PS50181)    SEC7 (PS50190)   
Domains : Interpro (EBI)F-box_dom    Sec7_alpha_orthog    Sec7_dom   
Domain families : Pfam (Sanger)F-box-like (PF12937)    Sec7 (PF01369)   
Domain families : Pfam (NCBI)pfam12937    pfam01369   
Domain families : Smart (EMBL)Sec7 (SM00222)  
Conserved Domain (NCBI)FBXO8
DMDM Disease mutations26269
Blocks (Seattle)FBXO8
SuperfamilyQ9NRD0
Human Protein AtlasENSG00000164117
Peptide AtlasQ9NRD0
HPRD07293
IPIIPI00016355   IPI00440377   IPI00383464   IPI00965051   IPI00965351   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRD0
IntAct (EBI)Q9NRD0
FunCoupENSG00000164117
BioGRIDFBXO8
STRING (EMBL)FBXO8
ZODIACFBXO8
Ontologies - Pathways
QuickGOQ9NRD0
Ontology : AmiGOubiquitin ligase complex  ARF guanyl-nucleotide exchange factor activity  ubiquitin-dependent protein catabolic process  regulation of ARF protein signal transduction  positive regulation of GTPase activity  
Ontology : EGO-EBIubiquitin ligase complex  ARF guanyl-nucleotide exchange factor activity  ubiquitin-dependent protein catabolic process  regulation of ARF protein signal transduction  positive regulation of GTPase activity  
NDEx NetworkFBXO8
Atlas of Cancer Signalling NetworkFBXO8
Wikipedia pathwaysFBXO8
Orthology - Evolution
OrthoDB26269
GeneTree (enSembl)ENSG00000164117
Phylogenetic Trees/Animal Genes : TreeFamFBXO8
HOVERGENQ9NRD0
HOGENOMQ9NRD0
Homologs : HomoloGeneFBXO8
Homology/Alignments : Family Browser (UCSC)FBXO8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFBXO8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FBXO8
dbVarFBXO8
ClinVarFBXO8
1000_GenomesFBXO8 
Exome Variant ServerFBXO8
ExAC (Exome Aggregation Consortium)FBXO8 (select the gene name)
Genetic variants : HAPMAP26269
Genomic Variants (DGV)FBXO8 [DGVbeta]
DECIPHER (Syndromes)4:175157810-175205402  ENSG00000164117
CONAN: Copy Number AnalysisFBXO8 
Mutations
ICGC Data PortalFBXO8 
TCGA Data PortalFBXO8 
Broad Tumor PortalFBXO8
OASIS PortalFBXO8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFBXO8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFBXO8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FBXO8
DgiDB (Drug Gene Interaction Database)FBXO8
DoCM (Curated mutations)FBXO8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FBXO8 (select a term)
intoGenFBXO8
Cancer3DFBXO8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605649   
Orphanet
MedgenFBXO8
Genetic Testing Registry FBXO8
NextProtQ9NRD0 [Medical]
TSGene26269
GENETestsFBXO8
Huge Navigator FBXO8 [HugePedia]
snp3D : Map Gene to Disease26269
BioCentury BCIQFBXO8
ClinGenFBXO8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26269
Chemical/Pharm GKB GenePA28048
Clinical trialFBXO8
Miscellaneous
canSAR (ICR)FBXO8 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFBXO8
EVEXFBXO8
GoPubMedFBXO8
iHOPFBXO8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:01:01 CEST 2017

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