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FMO1 (flavin containing monooxygenase 1)

Identity

Other alias-
HGNC (Hugo) FMO1
LocusID (NCBI) 2326
Atlas_Id 40614
Location 1q24.3  [Link to chromosome band 1q24]
Location_base_pair Starts at 171257923 and ends at 171285978 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FMO1   3769
Cards
Entrez_Gene (NCBI)FMO1  2326  flavin containing monooxygenase 1
Aliases
GeneCards (Weizmann)FMO1
Ensembl hg19 (Hinxton)ENSG00000010932 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000010932 [Gene_View]  chr1:171257923-171285978 [Contig_View]  FMO1 [Vega]
ICGC DataPortalENSG00000010932
TCGA cBioPortalFMO1
AceView (NCBI)FMO1
Genatlas (Paris)FMO1
WikiGenes2326
SOURCE (Princeton)FMO1
Genetics Home Reference (NIH)FMO1
Genomic and cartography
GoldenPath hg38 (UCSC)FMO1  -     chr1:171257923-171285978 +  1q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FMO1  -     1q24.3   [Description]    (hg19-Feb_2009)
EnsemblFMO1 - 1q24.3 [CytoView hg19]  FMO1 - 1q24.3 [CytoView hg38]
Mapping of homologs : NCBIFMO1 [Mapview hg19]  FMO1 [Mapview hg38]
OMIM136130   
Gene and transcription
Genbank (Entrez)AK097039 AK290113 AK296198 AK315100 BC047129
RefSeq transcript (Entrez)NM_001282692 NM_001282693 NM_001282694 NM_002021
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FMO1
Cluster EST : UnigeneHs.1424 [ NCBI ]
CGAP (NCI)Hs.1424
Alternative Splicing GalleryENSG00000010932
Gene ExpressionFMO1 [ NCBI-GEO ]   FMO1 [ EBI - ARRAY_EXPRESS ]   FMO1 [ SEEK ]   FMO1 [ MEM ]
Gene Expression Viewer (FireBrowse)FMO1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2326
GTEX Portal (Tissue expression)FMO1
Human Protein AtlasENSG00000010932-FMO1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ01740   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ01740  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ01740
Splice isoforms : SwissVarQ01740
Catalytic activity : Enzyme1.14.13.8 [ Enzyme-Expasy ]   1.14.13.81.14.13.8 [ IntEnz-EBI ]   1.14.13.8 [ BRENDA ]   1.14.13.8 [ KEGG ]   
PhosPhoSitePlusQ01740
Domains : Interpro (EBI)DiMe-aniline_mOase    FAD/NAD-binding_dom    Flavin_mOase    Flavin_mOase-like    Flavin_mOase_1    NAD(P)-bd_dom   
Domain families : Pfam (Sanger)FMO-like (PF00743)   
Domain families : Pfam (NCBI)pfam00743   
Conserved Domain (NCBI)FMO1
DMDM Disease mutations2326
Blocks (Seattle)FMO1
SuperfamilyQ01740
Human Protein Atlas [tissue]ENSG00000010932-FMO1 [tissue]
Peptide AtlasQ01740
HPRD00631
IPIIPI00182179   IPI00922643   IPI00642823   
Protein Interaction databases
DIP (DOE-UCLA)Q01740
IntAct (EBI)Q01740
FunCoupENSG00000010932
BioGRIDFMO1
STRING (EMBL)FMO1
ZODIACFMO1
Ontologies - Pathways
QuickGOQ01740
Ontology : AmiGOmonooxygenase activity  N,N-dimethylaniline monooxygenase activity  N,N-dimethylaniline monooxygenase activity  protein binding  endoplasmic reticulum lumen  endoplasmic reticulum membrane  organic acid metabolic process  xenobiotic metabolic process  response to osmotic stress  toxin metabolic process  integral component of membrane  drug metabolic process  organelle membrane  response to lipopolysaccharide  flavin adenine dinucleotide binding  NADP binding  NADPH oxidation  
Ontology : EGO-EBImonooxygenase activity  N,N-dimethylaniline monooxygenase activity  N,N-dimethylaniline monooxygenase activity  protein binding  endoplasmic reticulum lumen  endoplasmic reticulum membrane  organic acid metabolic process  xenobiotic metabolic process  response to osmotic stress  toxin metabolic process  integral component of membrane  drug metabolic process  organelle membrane  response to lipopolysaccharide  flavin adenine dinucleotide binding  NADP binding  NADPH oxidation  
Pathways : KEGGDrug metabolism - cytochrome P450   
NDEx NetworkFMO1
Atlas of Cancer Signalling NetworkFMO1
Wikipedia pathwaysFMO1
Orthology - Evolution
OrthoDB2326
GeneTree (enSembl)ENSG00000010932
Phylogenetic Trees/Animal Genes : TreeFamFMO1
HOVERGENQ01740
HOGENOMQ01740
Homologs : HomoloGeneFMO1
Homology/Alignments : Family Browser (UCSC)FMO1
Gene fusions - Rearrangements
Fusion: Tumor Portal FMO1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFMO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FMO1
dbVarFMO1
ClinVarFMO1
1000_GenomesFMO1 
Exome Variant ServerFMO1
ExAC (Exome Aggregation Consortium)ENSG00000010932
GNOMAD BrowserENSG00000010932
Genetic variants : HAPMAP2326
Genomic Variants (DGV)FMO1 [DGVbeta]
DECIPHERFMO1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFMO1 
Mutations
ICGC Data PortalFMO1 
TCGA Data PortalFMO1 
Broad Tumor PortalFMO1
OASIS PortalFMO1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFMO1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFMO1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FMO1
DgiDB (Drug Gene Interaction Database)FMO1
DoCM (Curated mutations)FMO1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FMO1 (select a term)
intoGenFMO1
Cancer3DFMO1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM136130   
Orphanet
MedgenFMO1
Genetic Testing Registry FMO1
NextProtQ01740 [Medical]
TSGene2326
GENETestsFMO1
Target ValidationFMO1
Huge Navigator FMO1 [HugePedia]
snp3D : Map Gene to Disease2326
BioCentury BCIQFMO1
ClinGenFMO1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2326
Chemical/Pharm GKB GenePA165
Clinical trialFMO1
Miscellaneous
canSAR (ICR)FMO1 (select the gene name)
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFMO1
EVEXFMO1
GoPubMedFMO1
iHOPFMO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 12:50:15 CET 2017

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