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FMO3 (flavin containing dimethylaniline monoxygenase 3)

Identity

Alias (NCBI)FMOII
TMAU
dJ127D3.1
HGNC (Hugo) FMO3
HGNC Alias symbFMOII
HGNC Alias nameDimethylaniline monooxygenase [N-oxide-forming] 3
HGNC Previous nameflavin containing monooxygenase 3
LocusID (NCBI) 2328
Atlas_Id 45891
Location 1q24.3  [Link to chromosome band 1q24]
Location_base_pair Starts at 171090905 and ends at 171117819 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)FMO3   3771
Cards
Entrez_Gene (NCBI)FMO3    flavin containing dimethylaniline monoxygenase 3
AliasesFMOII; TMAU; dJ127D3.1
GeneCards (Weizmann)FMO3
Ensembl hg19 (Hinxton)ENSG00000007933 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000007933 [Gene_View]  ENSG00000007933 [Sequence]  chr1:171090905-171117819 [Contig_View]  FMO3 [Vega]
ICGC DataPortalENSG00000007933
TCGA cBioPortalFMO3
AceView (NCBI)FMO3
Genatlas (Paris)FMO3
SOURCE (Princeton)FMO3
Genetics Home Reference (NIH)FMO3
Genomic and cartography
GoldenPath hg38 (UCSC)FMO3  -     chr1:171090905-171117819 +  1q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FMO3  -     1q24.3   [Description]    (hg19-Feb_2009)
GoldenPathFMO3 - 1q24.3 [CytoView hg19]  FMO3 - 1q24.3 [CytoView hg38]
ImmunoBaseENSG00000007933
Genome Data Viewer NCBIFMO3 [Mapview hg19]  
OMIM136132   602079   
Gene and transcription
Genbank (Entrez)AI478384 AK223166 AK296105 AK298406 AK310785
RefSeq transcript (Entrez)NM_001002294 NM_001319173 NM_001319174 NM_006894
Consensus coding sequences : CCDS (NCBI)FMO3
Gene ExpressionFMO3 [ NCBI-GEO ]   FMO3 [ EBI - ARRAY_EXPRESS ]   FMO3 [ SEEK ]   FMO3 [ MEM ]
Gene Expression Viewer (FireBrowse)FMO3 [ Firebrowse - Broad ]
GenevisibleExpression of FMO3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2328
GTEX Portal (Tissue expression)FMO3
Human Protein AtlasENSG00000007933-FMO3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP31513   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP31513  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP31513
PhosPhoSitePlusP31513
Domains : Interpro (EBI)FAD/NAD-bd_sf    Flavin_mOase    Flavin_mOase-like    Flavin_mOase_3   
Domain families : Pfam (Sanger)FMO-like (PF00743)   
Domain families : Pfam (NCBI)pfam00743   
Conserved Domain (NCBI)FMO3
SuperfamilyP31513
AlphaFold pdb e-kbP31513   
Human Protein Atlas [tissue]ENSG00000007933-FMO3 [tissue]
HPRD00633
Protein Interaction databases
DIP (DOE-UCLA)P31513
IntAct (EBI)P31513
BioGRIDFMO3
STRING (EMBL)FMO3
ZODIACFMO3
Ontologies - Pathways
QuickGOP31513
Ontology : AmiGOmonooxygenase activity  N,N-dimethylaniline monooxygenase activity  protein binding  endoplasmic reticulum membrane  xenobiotic metabolic process  integral component of membrane  trimethylamine monooxygenase activity  intracellular membrane-bounded organelle  flavin adenine dinucleotide binding  NADP binding  
Ontology : EGO-EBImonooxygenase activity  N,N-dimethylaniline monooxygenase activity  protein binding  endoplasmic reticulum membrane  xenobiotic metabolic process  integral component of membrane  trimethylamine monooxygenase activity  intracellular membrane-bounded organelle  flavin adenine dinucleotide binding  NADP binding  
Pathways : KEGGDrug metabolism - cytochrome P450   
NDEx NetworkFMO3
Atlas of Cancer Signalling NetworkFMO3
Wikipedia pathwaysFMO3
Orthology - Evolution
OrthoDB2328
GeneTree (enSembl)ENSG00000007933
Phylogenetic Trees/Animal Genes : TreeFamFMO3
Homologs : HomoloGeneFMO3
Homology/Alignments : Family Browser (UCSC)FMO3
Gene fusions - Rearrangements
Fusion : QuiverFMO3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFMO3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FMO3
dbVarFMO3
ClinVarFMO3
MonarchFMO3
1000_GenomesFMO3 
Exome Variant ServerFMO3
GNOMAD BrowserENSG00000007933
Varsome BrowserFMO3
ACMGFMO3 variants
VarityP31513
Genomic Variants (DGV)FMO3 [DGVbeta]
DECIPHERFMO3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFMO3 
Mutations
ICGC Data PortalFMO3 
TCGA Data PortalFMO3 
Broad Tumor PortalFMO3
OASIS PortalFMO3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFMO3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DFMO3
Mutations and Diseases : HGMDFMO3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaFMO3
DgiDB (Drug Gene Interaction Database)FMO3
DoCM (Curated mutations)FMO3
CIViC (Clinical Interpretations of Variants in Cancer)FMO3
Cancer3DFMO3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM136132    602079   
Orphanet
DisGeNETFMO3
MedgenFMO3
Genetic Testing Registry FMO3
NextProtP31513 [Medical]
GENETestsFMO3
Target ValidationFMO3
Huge Navigator FMO3 [HugePedia]
ClinGenFMO3
Clinical trials, drugs, therapy
MyCancerGenomeFMO3
Protein Interactions : CTDFMO3
Pharm GKB GenePA166
Pharm GKB PathwaysPA145011119   PA165374494   PA2011   
PharosP31513
Clinical trialFMO3
Miscellaneous
canSAR (ICR)FMO3
HarmonizomeFMO3
DataMed IndexFMO3
Probes
Litterature
PubMed122 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXFMO3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:09:41 CEST 2021

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