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FMO3 (flavin containing monooxygenase 3)

Identity

Other namesFMOII
TMAU
dJ127D3.1
HGNC (Hugo) FMO3
LocusID (NCBI) 2328
Location 1q24.3
Location_base_pair Starts at 171060018 and ends at 171086959 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)FMO3   3771
Cards
Entrez_Gene (NCBI)FMO3  2328  flavin containing monooxygenase 3
GeneCards (Weizmann)FMO3
Ensembl (Hinxton)ENSG00000007933 [Gene_View]  chr1:171060018-171086959 [Contig_View]  FMO3 [Vega]
ICGC DataPortalENSG00000007933
cBioPortalFMO3
AceView (NCBI)FMO3
Genatlas (Paris)FMO3
WikiGenes2328
SOURCE (Princeton)NM_001002294 NM_006894
Genomic and cartography
GoldenPath (UCSC)FMO3  -  1q24.3   chr1:171060018-171086959 +  1q24.3   [Description]    (hg19-Feb_2009)
EnsemblFMO3 - 1q24.3 [CytoView]
Mapping of homologs : NCBIFMO3 [Mapview]
OMIM136132   602079   
Gene and transcription
Genbank (Entrez)AI478384 AK223166 AK296105 AK298406 AK310785
RefSeq transcript (Entrez)NM_001002294 NM_006894
RefSeq genomic (Entrez)AC_000133 NC_000001 NC_018912 NG_012690 NT_004487 NW_001838533 NW_004929293
Consensus coding sequences : CCDS (NCBI)FMO3
Cluster EST : UnigeneHs.445350 [ NCBI ]
CGAP (NCI)Hs.445350
Alternative Splicing : Fast-db (Paris)GSHG0001182
Alternative Splicing GalleryENSG00000007933
Gene ExpressionFMO3 [ NCBI-GEO ]     FMO3 [ SEEK ]   FMO3 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP31513 (Uniprot)
NextProtP31513  [Medical]
With graphics : InterProP31513
Splice isoforms : SwissVarP31513 (Swissvar)
Catalytic activity : Enzyme1.14.13.8 [ Enzyme-Expasy ]   1.14.13.81.14.13.8 [ IntEnz-EBI ]   1.14.13.8 [ BRENDA ]   1.14.13.8 [ KEGG ]   
Domains : Interpro (EBI)DiMe-aniline_mOase [organisation]   Flavin_mOase [organisation]   Flavin_mOase-like [organisation]   Flavin_mOase_3 [organisation]  
Related proteins : CluSTrP31513
Domain families : Pfam (Sanger)FMO-like (PF00743)   
Domain families : Pfam (NCBI)pfam00743   
DMDM Disease mutations2328
Blocks (Seattle)P31513
Human Protein AtlasENSG00000007933 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP31513
HPRD00633
IPIIPI00329033   IPI00922176   IPI01015963   
Protein Interaction databases
DIP (DOE-UCLA)P31513
IntAct (EBI)P31513
FunCoupENSG00000007933
BioGRIDFMO3
InParanoidP31513
Interologous Interaction database P31513
IntegromeDBFMO3
STRING (EMBL)FMO3
Ontologies - Pathways
Ontology : AmiGON,N-dimethylaniline monooxygenase activity  endoplasmic reticulum membrane  xenobiotic metabolic process  integral to membrane  amino acid binding  drug metabolic process  trimethylamine monooxygenase activity  intracellular membrane-bounded organelle  small molecule metabolic process  flavin adenine dinucleotide binding  NADP binding  
Ontology : EGO-EBIN,N-dimethylaniline monooxygenase activity  endoplasmic reticulum membrane  xenobiotic metabolic process  integral to membrane  amino acid binding  drug metabolic process  trimethylamine monooxygenase activity  intracellular membrane-bounded organelle  small molecule metabolic process  flavin adenine dinucleotide binding  NADP binding  
Pathways : KEGGDrug metabolism - cytochrome P450   
Protein Interaction DatabaseFMO3
Wikipedia pathwaysFMO3
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)FMO3
snp3D : Map Gene to Disease2328
SNP (GeneSNP Utah)FMO3
SNP : HGBaseFMO3
Genetic variants : HAPMAPFMO3
Exome VariantFMO3
1000_GenomesFMO3 
ICGC programENSG00000007933 
Somatic Mutations in Cancer : COSMICFMO3 
CONAN: Copy Number AnalysisFMO3 
Mutations and Diseases : HGMDFMO3
Genomic VariantsFMO3  FMO3 [DGVbeta]
dbVarFMO3
ClinVarFMO3
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM136132    602079   
MedgenFMO3
GENETestsFMO3
Disease Genetic AssociationFMO3
Huge Navigator FMO3 [HugePedia]  FMO3 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneFMO3
Homology/Alignments : Family Browser (UCSC)FMO3
Phylogenetic Trees/Animal Genes : TreeFamFMO3
Chemical/Protein Interactions : CTD2328
Chemical/Pharm GKB GenePA166
Clinical trialFMO3
Cancer Resource (Charite)ENSG00000007933
Other databases
Probes
Litterature
PubMed81 Pubmed reference(s) in Entrez
CoreMineFMO3
iHOPFMO3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 16:56:04 CEST 2014

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