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FUT3 (fucosyltransferase 3 (Lewis blood group))

Identity

Alias_namesLE
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase
Alias_symbol (synonym)CD174
Other aliasFT3B
FucT-III
Les
HGNC (Hugo) FUT3
LocusID (NCBI) 2525
Atlas_Id 43830
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 5842888 and ends at 5851474 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FUT3 (19p13.3) / FN1 (2q35)FUT3 (19p13.3) / FUT3 (19p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)FUT3   4014
LRG (Locus Reference Genomic)LRG_800
Cards
Entrez_Gene (NCBI)FUT3  2525  fucosyltransferase 3 (Lewis blood group)
AliasesCD174; FT3B; FucT-III; LE; 
Les
GeneCards (Weizmann)FUT3
Ensembl hg19 (Hinxton)ENSG00000171124 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000171124 [Gene_View]  chr19:5842888-5851474 [Contig_View]  FUT3 [Vega]
ICGC DataPortalENSG00000171124
TCGA cBioPortalFUT3
AceView (NCBI)FUT3
Genatlas (Paris)FUT3
WikiGenes2525
SOURCE (Princeton)FUT3
Genetics Home Reference (NIH)FUT3
Genomic and cartography
GoldenPath hg38 (UCSC)FUT3  -     chr19:5842888-5851474 -  19p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)FUT3  -     19p13.3   [Description]    (hg19-Feb_2009)
EnsemblFUT3 - 19p13.3 [CytoView hg19]  FUT3 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBIFUT3 [Mapview hg19]  FUT3 [Mapview hg38]
OMIM111100   
Gene and transcription
Genbank (Entrez)AF131913 AK291852 AK313575 BC074836 BC074837
RefSeq transcript (Entrez)NM_000149 NM_001097639 NM_001097640 NM_001097641
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)FUT3
Cluster EST : UnigeneHs.169238 [ NCBI ]
CGAP (NCI)Hs.169238
Alternative Splicing GalleryENSG00000171124
Gene ExpressionFUT3 [ NCBI-GEO ]   FUT3 [ EBI - ARRAY_EXPRESS ]   FUT3 [ SEEK ]   FUT3 [ MEM ]
Gene Expression Viewer (FireBrowse)FUT3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2525
GTEX Portal (Tissue expression)FUT3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP21217   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP21217  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP21217
Splice isoforms : SwissVarP21217
Catalytic activity : Enzyme2.4.1.65 [ Enzyme-Expasy ]   2.4.1.652.4.1.65 [ IntEnz-EBI ]   2.4.1.65 [ BRENDA ]   2.4.1.65 [ KEGG ]   
PhosPhoSitePlusP21217
Domains : Interpro (EBI)Glyco_tran_10_N    Glyco_trans_10   
Domain families : Pfam (Sanger)Glyco_tran_10_N (PF17039)    Glyco_transf_10 (PF00852)   
Domain families : Pfam (NCBI)pfam17039    pfam00852   
Conserved Domain (NCBI)FUT3
DMDM Disease mutations2525
Blocks (Seattle)FUT3
SuperfamilyP21217
Human Protein AtlasENSG00000171124
Peptide AtlasP21217
HPRD00196
IPIIPI00007671   
Protein Interaction databases
DIP (DOE-UCLA)P21217
IntAct (EBI)P21217
FunCoupENSG00000171124
BioGRIDFUT3
STRING (EMBL)FUT3
ZODIACFUT3
Ontologies - Pathways
QuickGOP21217
Ontology : AmiGOGolgi membrane  Golgi membrane  protein glycosylation  fucosyltransferase activity  oligosaccharide biosynthetic process  cell-cell recognition  membrane  integral component of membrane  3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity  Golgi cisterna membrane  fucosylation  macromolecule glycosylation  alpha-(1->3)-fucosyltransferase activity  extracellular exosome  
Ontology : EGO-EBIGolgi membrane  Golgi membrane  protein glycosylation  fucosyltransferase activity  oligosaccharide biosynthetic process  cell-cell recognition  membrane  integral component of membrane  3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity  Golgi cisterna membrane  fucosylation  macromolecule glycosylation  alpha-(1->3)-fucosyltransferase activity  extracellular exosome  
Pathways : KEGGGlycosphingolipid biosynthesis - lacto and neolacto series   
NDEx NetworkFUT3
Atlas of Cancer Signalling NetworkFUT3
Wikipedia pathwaysFUT3
Orthology - Evolution
OrthoDB2525
GeneTree (enSembl)ENSG00000171124
Phylogenetic Trees/Animal Genes : TreeFamFUT3
HOVERGENP21217
HOGENOMP21217
Homologs : HomoloGeneFUT3
Homology/Alignments : Family Browser (UCSC)FUT3
Gene fusions - Rearrangements
Fusion Cancer (Beijing)FUT3 [19p13.3]  -  FN1 [2q35]  [FUSC002154]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerFUT3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)FUT3
dbVarFUT3
ClinVarFUT3
1000_GenomesFUT3 
Exome Variant ServerFUT3
ExAC (Exome Aggregation Consortium)FUT3 (select the gene name)
Genetic variants : HAPMAP2525
Genomic Variants (DGV)FUT3 [DGVbeta]
DECIPHERFUT3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisFUT3 
Mutations
ICGC Data PortalFUT3 
TCGA Data PortalFUT3 
Broad Tumor PortalFUT3
OASIS PortalFUT3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICFUT3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDFUT3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch FUT3
DgiDB (Drug Gene Interaction Database)FUT3
DoCM (Curated mutations)FUT3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)FUT3 (select a term)
intoGenFUT3
Cancer3DFUT3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM111100   
Orphanet
MedgenFUT3
Genetic Testing Registry FUT3
NextProtP21217 [Medical]
TSGene2525
GENETestsFUT3
Target ValidationFUT3
Huge Navigator FUT3 [HugePedia]
snp3D : Map Gene to Disease2525
BioCentury BCIQFUT3
ClinGenFUT3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2525
Chemical/Pharm GKB GenePA28430
Clinical trialFUT3
Miscellaneous
canSAR (ICR)FUT3 (select the gene name)
Probes
Litterature
PubMed78 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineFUT3
EVEXFUT3
GoPubMedFUT3
iHOPFUT3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:09:06 CEST 2017

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