Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GABPA (GA binding protein transcription factor, alpha subunit 60kDa)

Identity

Other namesE4TF1-60
E4TF1A
NFT2
NRF2
NRF2A
RCH04A07
HGNC (Hugo) GABPA
LocusID (NCBI) 2551
Location 21q21.3
Location_base_pair Starts at 27107258 and ends at 27144771 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GABPA   4071
Entrez_Gene (NCBI)GABPA  2551  GA binding protein transcription factor, alpha subunit 60kDa
Cards
GeneCards (Weizmann)GABPA
Ensembl (Hinxton)ENSG00000154727 [Gene_View]  chr21:27107258-27144771 [Contig_View]  GABPA [Vega]
AceView (NCBI)GABPA
Genatlas (Paris)GABPA
SOURCE (Stanford)NM_001197297 NM_002040
Genomic and cartography
GoldenPath (UCSC)GABPA  -  21q21.3   chr21:27107258-27144771 +  21q21.3   [Description]    (hg19-Feb_2009)
EnsemblGABPA - 21q21.3 [CytoView]
Mapping of homologs : NCBIGABPA [Mapview]
OMIM600609   
Gene and transcription
Genbank (Entrez)AI917898 AK223164 AK313545 BC035031 BG542623
RefSeq transcript (SRS)NM_001197297 NM_002040
RefSeq transcript (Entrez)NM_001197297 NM_002040
RefSeq genomic (SRS)AC_000153 NC_000021 NC_018932 NT_011512 NW_001838706 NW_004078109
RefSeq genomic (Entrez)AC_000153 NC_000021 NC_018932 NT_011512 NW_001838706 NW_004078109
Consensus coding sequences : CCDS (NCBI)GABPA
Cluster EST : UnigeneHs.473470 [ SRS ] Hs.473470 [ NCBI ]
CGAP (NCI)Hs.473470
Alternative Splicing : Fast-db (Paris)GSHG0019383
Alternative Splicing GalleryENSG00000154727
Gene ExpressionGABPA [ NCBI-GEO ]   GABPA [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ06546 (SRS) Q06546 (Uniprot)
NextProtQ06546
With graphics : InterProQ06546
Splice isoforms : SwissVarQ06546(Swissvar)
Domaine pattern : Prosite (SRS)ETS_DOMAIN_1 (PS00345)    ETS_DOMAIN_2 (PS00346)    ETS_DOMAIN_3 (PS50061)    PNT (PS51433)   
Domaine pattern : Prosite (Expaxy)ETS_DOMAIN_1 (PS00345)    ETS_DOMAIN_2 (PS00346)    ETS_DOMAIN_3 (PS50061)    PNT (PS51433)   
Domains : Interpro (SRS)Ets    GABP_asu_N    Pointed_dom    SAM/pointed    TF_GA-bd_asu    WHTH_trsnscrt_rep_DNA-bd   
Domains : Interpro (EBI)Ets    GABP_asu_N    Pointed_dom    SAM/pointed    TF_GA-bd_asu    WHTH_trsnscrt_rep_DNA-bd   
Related proteins : CluSTrQ06546
Domain families : Pfam (SRS)Ets (PF00178)    GABP-alpha (PF11620)    SAM_PNT (PF02198)   
Domain families : Pfam (Sanger)Ets (PF00178)    GABP-alpha (PF11620)    SAM_PNT (PF02198)   
Domain families : Pfam (NCBI)pfam00178    pfam11620    pfam02198   
Domain families : Smart (EMBL)ETS (SM00413)  SAM_PNT (SM00251)  
DMDM2551
Blocks (Seattle)Q06546
Human Protein AtlasENSG00000154727
HPRD11793
IPIIPI00299413   
Protein Interaction databases
DIP (DOE-UCLA)Q06546
IntAct (EBI)Q06546
FunCoupENSG00000154727
REACTOMEGABPA
Protein Interaction Database2551
BioGRIDGABPA
InParanoidQ06546
Interologous Interaction database Q06546
IntegromeDBGABPA
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GABPA
SNP (GeneSNP Utah)GABPA
SNP : HGBaseGABPA
Genetic variants : HAPMAPGABPA
Somatic Mutations in Cancer : COSMICGABPA 
CONAN: Copy Number AnalysisGABPA 
Mutations and Diseases : HGMDGABPA
OMIM600609   
GENETests600609   
Disease Genetic AssociationGABPA
Huge Navigator GABPA [HugePedia]  GABPA [HugeCancerGEM]
Genomic VariantsGABPA  GABPA [DGVbeta]
snp3D : Map Gene to Disease2551
General knowledge
Homologs : HomoloGeneGABPA
Homology/Alignments : Family Browser (UCSC)GABPA
Phylogenetic Trees/Animal Genes : TreeFamGABPA
Chemical/Protein Interactions : CTD2551
Chemical/Pharm GKB GenePA28485
Clinical trialGABPA
Cancer Resource (Charite)ENSG00000154727
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  nuclear chromatin  RNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription  in utero embryonic development  DNA binding  sequence-specific DNA binding transcription factor activity  transcription coactivator activity  protein binding  nucleus  nucleolus  transcription from RNA polymerase II promoter  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  protein heterodimerization activity  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  nuclear chromatin  RNA polymerase II core promoter proximal region sequence-specific DNA binding  RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription  in utero embryonic development  DNA binding  sequence-specific DNA binding transcription factor activity  transcription coactivator activity  protein binding  nucleus  nucleolus  transcription from RNA polymerase II promoter  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  protein heterodimerization activity  
Other databases
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
PubGeneGABPA
iHOPGABPA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:33:07 CEST 2013
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