GGNBP2 (gametogenetin binding protein 2)

2007-02-01  

Identity

HGNC
LOCATION
17q12
LOCUSID
ALIAS
DIF-3,DIF3,LCRG1,LZK1,ZFP403,ZNF403
FUSION GENES

Other Information

Locus ID:

NCBI: 79893
MIM: 612275
HGNC: 19357
Ensembl: ENSG00000278311

Variants:

dbSNP: 79893
ClinVar: 79893
TCGA: ENSG00000278311
COSMIC: GGNBP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000278311ENST00000611219A0A087X0E5
ENSG00000278311ENST00000613102Q9H3C7
ENSG00000278311ENST00000615952A0A087X1N0
ENSG00000278311ENST00000616019A0A087X1D7

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
248421572014Downregulation of tumor suppressor gene ribonuclease T2 and gametogenetin binding protein 2 is associated with drug resistance in ovarian cancer.8
223508152012Knockdown of ZNF403 inhibits cell proliferation and induces G2/M arrest by modulating cell-cycle mediators.4
151455232004Molecular cloning and characterization of LCRG1 a novel gene localized to the tumor suppressor locus D17S800-D17S930.3
273578122016GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor α activity in breast cancer cells.3
288641312017ZFP403, a novel tumor suppressor, inhibits the proliferation and metastasis in ovarian cancer.3
304505302019GGNBP2 suppresses triple-negative breast cancer aggressiveness through inhibition of IL-6/STAT3 signaling activation.2

Citation

Dessen P

GGNBP2 (gametogenetin binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45910/ggnbp2