Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GINS2 (GINS complex subunit 2)

Identity

Alias_namesGINS complex subunit 2 (Psf2 homolog)
Alias_symbol (synonym)PSF2
Pfs2
Other aliasHSPC037
HGNC (Hugo) GINS2
LocusID (NCBI) 51659
Atlas_Id 52149
Location 16q24.1  [Link to chromosome band 16q24]
Location_base_pair Starts at 85677674 and ends at 85688982 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MED28 (4p15.32) / GINS2 (16q24.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GINS2   24575
Cards
Entrez_Gene (NCBI)GINS2  51659  GINS complex subunit 2
AliasesHSPC037; PSF2; Pfs2
GeneCards (Weizmann)GINS2
Ensembl hg19 (Hinxton)ENSG00000131153 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000131153 [Gene_View]  ENSG00000131153 [Sequence]  chr16:85677674-85688982 [Contig_View]  GINS2 [Vega]
ICGC DataPortalENSG00000131153
TCGA cBioPortalGINS2
AceView (NCBI)GINS2
Genatlas (Paris)GINS2
WikiGenes51659
SOURCE (Princeton)GINS2
Genetics Home Reference (NIH)GINS2
Genomic and cartography
GoldenPath hg38 (UCSC)GINS2  -     chr16:85677674-85688982 -  16q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GINS2  -     16q24.1   [Description]    (hg19-Feb_2009)
EnsemblGINS2 - 16q24.1 [CytoView hg19]  GINS2 - 16q24.1 [CytoView hg38]
Mapping of homologs : NCBIGINS2 [Mapview hg19]  GINS2 [Mapview hg38]
OMIM610609   
Gene and transcription
Genbank (Entrez)AF125098 AF151880 AF201939 AK001275 AK091519
RefSeq transcript (Entrez)NM_016095
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GINS2
Cluster EST : UnigeneHs.433180 [ NCBI ]
CGAP (NCI)Hs.433180
Alternative Splicing GalleryENSG00000131153
Gene ExpressionGINS2 [ NCBI-GEO ]   GINS2 [ EBI - ARRAY_EXPRESS ]   GINS2 [ SEEK ]   GINS2 [ MEM ]
Gene Expression Viewer (FireBrowse)GINS2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51659
GTEX Portal (Tissue expression)GINS2
Human Protein AtlasENSG00000131153-GINS2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y248   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y248  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y248
Splice isoforms : SwissVarQ9Y248
PhosPhoSitePlusQ9Y248
Domains : Interpro (EBI)GINS_A    GINS_Psf2   
Domain families : Pfam (Sanger)Sld5 (PF05916)   
Domain families : Pfam (NCBI)pfam05916   
Conserved Domain (NCBI)GINS2
DMDM Disease mutations51659
Blocks (Seattle)GINS2
PDB (SRS)2E9X    2EHO    2Q9Q   
PDB (PDBSum)2E9X    2EHO    2Q9Q   
PDB (IMB)2E9X    2EHO    2Q9Q   
PDB (RSDB)2E9X    2EHO    2Q9Q   
Structural Biology KnowledgeBase2E9X    2EHO    2Q9Q   
SCOP (Structural Classification of Proteins)2E9X    2EHO    2Q9Q   
CATH (Classification of proteins structures)2E9X    2EHO    2Q9Q   
SuperfamilyQ9Y248
Human Protein Atlas [tissue]ENSG00000131153-GINS2 [tissue]
Peptide AtlasQ9Y248
HPRD15197
IPIIPI00007146   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y248
IntAct (EBI)Q9Y248
FunCoupENSG00000131153
BioGRIDGINS2
STRING (EMBL)GINS2
ZODIACGINS2
Ontologies - Pathways
QuickGOQ9Y248
Ontology : AmiGOdouble-strand break repair via break-induced replication  GINS complex  protein binding  nucleoplasm  DNA strand elongation involved in DNA replication  replication fork protection complex  DNA duplex unwinding  3'-5' DNA helicase activity  mitotic DNA replication initiation  
Ontology : EGO-EBIdouble-strand break repair via break-induced replication  GINS complex  protein binding  nucleoplasm  DNA strand elongation involved in DNA replication  replication fork protection complex  DNA duplex unwinding  3'-5' DNA helicase activity  mitotic DNA replication initiation  
NDEx NetworkGINS2
Atlas of Cancer Signalling NetworkGINS2
Wikipedia pathwaysGINS2
Orthology - Evolution
OrthoDB51659
GeneTree (enSembl)ENSG00000131153
Phylogenetic Trees/Animal Genes : TreeFamGINS2
HOVERGENQ9Y248
HOGENOMQ9Y248
Homologs : HomoloGeneGINS2
Homology/Alignments : Family Browser (UCSC)GINS2
Gene fusions - Rearrangements
Fusion : QuiverGINS2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGINS2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GINS2
dbVarGINS2
ClinVarGINS2
1000_GenomesGINS2 
Exome Variant ServerGINS2
ExAC (Exome Aggregation Consortium)ENSG00000131153
GNOMAD BrowserENSG00000131153
Genetic variants : HAPMAP51659
Genomic Variants (DGV)GINS2 [DGVbeta]
DECIPHERGINS2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGINS2 
Mutations
ICGC Data PortalGINS2 
TCGA Data PortalGINS2 
Broad Tumor PortalGINS2
OASIS PortalGINS2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGINS2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGINS2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GINS2
DgiDB (Drug Gene Interaction Database)GINS2
DoCM (Curated mutations)GINS2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GINS2 (select a term)
intoGenGINS2
Cancer3DGINS2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610609   
Orphanet
DisGeNETGINS2
MedgenGINS2
Genetic Testing Registry GINS2
NextProtQ9Y248 [Medical]
TSGene51659
GENETestsGINS2
Target ValidationGINS2
Huge Navigator GINS2 [HugePedia]
snp3D : Map Gene to Disease51659
BioCentury BCIQGINS2
ClinGenGINS2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51659
Chemical/Pharm GKB GenePA145008313
Clinical trialGINS2
Miscellaneous
canSAR (ICR)GINS2 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGINS2
EVEXGINS2
GoPubMedGINS2
iHOPGINS2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Jun 22 16:27:12 CEST 2018
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