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GLIS3 (GLIS family zinc finger 3)

Identity

Alias_namesZNF515
zinc finger protein 515
Alias_symbol (synonym)MGC33662
Other aliasNDH
HGNC (Hugo) GLIS3
LocusID (NCBI) 169792
Atlas_Id 55386
Location 9p24.2  [Link to chromosome band 9p24]
Location_base_pair Starts at 3824128 and ends at 4300035 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AC011450.1 () / GLIS3 (9p24.2)GLIS3 (9p24.2) / ARHGAP1 (11p11.2)GLIS3 (9p24.2) / CTNNA2 (2p12)
GLIS3 (9p24.2) / GLIS3 (9p24.2)GLIS3 (9p24.2) / PLGRKT (9p24.1)GLIS3 (9p24.2) / PUM3 (9p24.2)
GLIS3 (9p24.2) / RCL1 (9p24.1)RAP1GAP (1p36.12) / GLIS3 (9p24.2)AC011450.1 GLIS3 9p24.2
GLIS3 9p24.2 / ARHGAP1 11p11.2GLIS3 9p24.2 C9orf46GLIS3 9p24.2 / CTNNA2 2p12
GLIS3 9p24.2 / KIAA0020 9p24.2GLIS3 9p24.2 / RCL1 9p24.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GLIS3   28510
Cards
Entrez_Gene (NCBI)GLIS3  169792  GLIS family zinc finger 3
AliasesNDH; ZNF515
GeneCards (Weizmann)GLIS3
Ensembl hg19 (Hinxton)ENSG00000107249 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000107249 [Gene_View]  chr9:3824128-4300035 [Contig_View]  GLIS3 [Vega]
ICGC DataPortalENSG00000107249
TCGA cBioPortalGLIS3
AceView (NCBI)GLIS3
Genatlas (Paris)GLIS3
WikiGenes169792
SOURCE (Princeton)GLIS3
Genetics Home Reference (NIH)GLIS3
Genomic and cartography
GoldenPath hg38 (UCSC)GLIS3  -     chr9:3824128-4300035 -  9p24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GLIS3  -     9p24.2   [Description]    (hg19-Feb_2009)
EnsemblGLIS3 - 9p24.2 [CytoView hg19]  GLIS3 - 9p24.2 [CytoView hg38]
Mapping of homologs : NCBIGLIS3 [Mapview hg19]  GLIS3 [Mapview hg38]
OMIM610192   610199   
Gene and transcription
Genbank (Entrez)###############################################################################################################################################################################################################################################################
RefSeq transcript (Entrez)NM_001042413 NM_152629
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GLIS3
Cluster EST : UnigeneHs.644570 [ NCBI ]
CGAP (NCI)Hs.644570
Alternative Splicing GalleryENSG00000107249
Gene ExpressionGLIS3 [ NCBI-GEO ]   GLIS3 [ EBI - ARRAY_EXPRESS ]   GLIS3 [ SEEK ]   GLIS3 [ MEM ]
Gene Expression Viewer (FireBrowse)GLIS3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)169792
GTEX Portal (Tissue expression)GLIS3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NEA6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NEA6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NEA6
Splice isoforms : SwissVarQ8NEA6
PhosPhoSitePlusQ8NEA6
Domaine pattern : Prosite (Expaxy)ZINC_FINGER_C2H2_1 (PS00028)    ZINC_FINGER_C2H2_2 (PS50157)   
Domains : Interpro (EBI)GLIS3    Znf_C2H2    Znf_C2H2-like    Znf_C2H2/integrase_DNA-bd   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)ZnF_C2H2 (SM00355)  
Conserved Domain (NCBI)GLIS3
DMDM Disease mutations169792
Blocks (Seattle)GLIS3
SuperfamilyQ8NEA6
Human Protein AtlasENSG00000107249
Peptide AtlasQ8NEA6
HPRD13582
IPIIPI00168641   IPI00761097   IPI00816004   IPI00946240   IPI00954587   IPI00744491   IPI00844273   IPI00169355   IPI00947201   IPI00946408   IPI01021373   
Protein Interaction databases
DIP (DOE-UCLA)Q8NEA6
IntAct (EBI)Q8NEA6
FunCoupENSG00000107249
BioGRIDGLIS3
STRING (EMBL)GLIS3
ZODIACGLIS3
Ontologies - Pathways
QuickGOQ8NEA6
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  DNA binding  nucleus  transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  DNA binding  nucleus  transcription from RNA polymerase II promoter  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  
NDEx NetworkGLIS3
Atlas of Cancer Signalling NetworkGLIS3
Wikipedia pathwaysGLIS3
Orthology - Evolution
OrthoDB169792
GeneTree (enSembl)ENSG00000107249
Phylogenetic Trees/Animal Genes : TreeFamGLIS3
HOVERGENQ8NEA6
HOGENOMQ8NEA6
Homologs : HomoloGeneGLIS3
Homology/Alignments : Family Browser (UCSC)GLIS3
Gene fusions - Rearrangements
Fusion : MitelmanGLIS3/ARHGAP1 [9p24.2/11p11.2]  
Fusion : MitelmanGLIS3/CTNNA2 [9p24.2/2p12]  [t(2;9)(p12;p24)]  
Fusion : MitelmanGLIS3/KIAA0020 [9p24.2/9p24.2]  [t(9;9)(p24;p24)]  
Fusion : MitelmanGLIS3/PLGRKT [9p24.2/9p24.1]  [t(9;9)(p24;p24)]  
Fusion : MitelmanGLIS3/RCL1 [9p24.2/9p24.1]  [t(9;9)(p24;p24)]  
Fusion: TCGAAC011450.1 GLIS3 9p24.2 BRCA
Fusion: TCGAGLIS3 9p24.2 ARHGAP1 11p11.2 LUAD
Fusion: TCGAGLIS3 9p24.2 C9orf46 KIRC
Fusion: TCGAGLIS3 9p24.2 CTNNA2 2p12 HNSC
Fusion: TCGAGLIS3 9p24.2 KIAA0020 9p24.2 LGG
Fusion: TCGAGLIS3 9p24.2 RCL1 9p24.1 KIRC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGLIS3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GLIS3
dbVarGLIS3
ClinVarGLIS3
1000_GenomesGLIS3 
Exome Variant ServerGLIS3
ExAC (Exome Aggregation Consortium)GLIS3 (select the gene name)
Genetic variants : HAPMAP169792
Genomic Variants (DGV)GLIS3 [DGVbeta]
DECIPHERGLIS3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGLIS3 
Mutations
ICGC Data PortalGLIS3 
TCGA Data PortalGLIS3 
Broad Tumor PortalGLIS3
OASIS PortalGLIS3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGLIS3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGLIS3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GLIS3
DgiDB (Drug Gene Interaction Database)GLIS3
DoCM (Curated mutations)GLIS3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GLIS3 (select a term)
intoGenGLIS3
Cancer3DGLIS3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610192    610199   
Orphanet11151   
MedgenGLIS3
Genetic Testing Registry GLIS3
NextProtQ8NEA6 [Medical]
TSGene169792
GENETestsGLIS3
Target ValidationGLIS3
Huge Navigator GLIS3 [HugePedia]
snp3D : Map Gene to Disease169792
BioCentury BCIQGLIS3
ClinGenGLIS3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD169792
Chemical/Pharm GKB GenePA134878768
Clinical trialGLIS3
Miscellaneous
canSAR (ICR)GLIS3 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGLIS3
EVEXGLIS3
GoPubMedGLIS3
iHOPGLIS3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:02:06 CEST 2017

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