Atlas of Genetics and Cytogenetics in Oncology and Haematology

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   
X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GLO1 (glyoxalase I)

Identity

Other namesGLOD1
GLYI
HGNC (Hugo) GLO1
LocusID (NCBI) 2739
Location 6p21.2
Location_base_pair Starts at 38643702 and ends at 38670952 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GLO1   4323
Entrez_Gene (NCBI)GLO1  2739  glyoxalase I
Cards
GeneCards (Weizmann)GLO1
Ensembl (Hinxton)ENSG00000124767 [Gene_View]  chr6:38643702-38670952 [Contig_View]  GLO1 [Vega]
AceView (NCBI)GLO1
Genatlas (Paris)GLO1
SOURCE (Stanford)NM_006708
Genomic and cartography
GoldenPath (UCSC)GLO1  -  6p21.2   chr6:38643702-38670952 -  6p21.2   [Description]    (hg19-Feb_2009)
EnsemblGLO1 - 6p21.2 [CytoView]
Mapping of homologs : NCBIGLO1 [Mapview]
OMIM138750   209850   
Gene and transcription
Genbank (Entrez)AB209801 AK129573 AK130312 AK293345 AK312662
RefSeq transcript (SRS)NM_006708
RefSeq transcript (Entrez)NM_006708
RefSeq genomic (SRS)AC_000138 NC_000006 NC_018917 NG_012074 NT_007592 NW_001838980 NW_004078026
RefSeq genomic (Entrez)AC_000138 NC_000006 NC_018917 NG_012074 NT_007592 NW_001838980 NW_004078026
Consensus coding sequences : CCDS (NCBI)GLO1
Cluster EST : UnigeneHs.268849 [ SRS ] Hs.268849 [ NCBI ]
CGAP (NCI)Hs.268849
Alternative Splicing : Fast-db (Paris)GSHG0026581
Alternative Splicing GalleryENSG00000124767
Gene ExpressionGLO1 [ NCBI-GEO ]   GLO1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ04760 (SRS) Q04760 (Uniprot)
NextProtQ04760
With graphics : InterProQ04760
Splice isoforms : SwissVarQ04760(Swissvar)
Domaine pattern : Prosite (SRS)GLYOXALASE_I_1 (PS00934)    GLYOXALASE_I_2 (PS00935)   
Domaine pattern : Prosite (Expaxy)GLYOXALASE_I_1 (PS00934)    GLYOXALASE_I_2 (PS00935)   
Domains : Interpro (SRS)Glyas_Fos-R_dOase_dom    Glyoxalase_1    Glyoxalase_1_CS   
Domains : Interpro (EBI)Glyas_Fos-R_dOase_dom    Glyoxalase_1    Glyoxalase_1_CS   
Related proteins : CluSTrQ04760
Domain families : Pfam (SRS)Glyoxalase (PF00903)   
Domain families : Pfam (Sanger)Glyoxalase (PF00903)   
Domain families : Pfam (NCBI)pfam00903   
DMDM2739
Blocks (Seattle)Q04760
PDB (SRS)1BH5    1FRO    1QIN    1QIP   
PDB (PDBSum)1BH5    1FRO    1QIN    1QIP   
PDB (IMB)1BH5    1FRO    1QIN    1QIP   
PDB (RSDB)1BH5    1FRO    1QIN    1QIP   
Human Protein AtlasENSG00000124767
HPRD00730
IPIIPI00220766   IPI01021703   
Protein Interaction databases
DIP (DOE-UCLA)Q04760
IntAct (EBI)Q04760
FunCoupENSG00000124767
REACTOMEGLO1
Protein Interaction Database2739
BioGRIDGLO1
InParanoidQ04760
Interologous Interaction database Q04760
IntegromeDBGLO1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GLO1
SNP (GeneSNP Utah)GLO1
SNP : HGBaseGLO1
Genetic variants : HAPMAPGLO1
Somatic Mutations in Cancer : COSMICGLO1 
CONAN: Copy Number AnalysisGLO1 
Mutations and Diseases : HGMDGLO1
OMIM138750    209850   
GENETests138750    209850   
Disease Genetic AssociationGLO1
Huge Navigator GLO1 [HugePedia]  GLO1 [HugeCancerGEM]
Genomic VariantsGLO1  GLO1 [DGVbeta]
snp3D : Map Gene to Disease2739
General knowledge
Homologs : HomoloGeneGLO1
Homology/Alignments : Family Browser (UCSC)GLO1
Phylogenetic Trees/Animal Genes : TreeFamGLO1
Catalytic activity : Enzyme4.4.1.5 [ Enzyme-Expasy ]   4.4.1.5 [ Enzyme-SRS ]   4.4.1.5 [ IntEnz-EBI ]   4.4.1.5 [ BRENDA ]   4.4.1.5 [ KEGG ]   
Chemical/Protein Interactions : CTD2739
Chemical/Pharm GKB GenePA28724
Clinical trialGLO1
Cancer Resource (Charite)ENSG00000124767
Ontology : AmiGOlactoylglutathione lyase activity  cytoplasm  carbohydrate metabolic process  regulation of transcription from RNA polymerase II promoter  glutathione metabolic process  methylglyoxal metabolic process  negative regulation of apoptotic process  negative regulation of apoptotic process  negative regulation of apoptotic process  metal ion binding  
Ontology : EGO-EBIlactoylglutathione lyase activity  cytoplasm  carbohydrate metabolic process  regulation of transcription from RNA polymerase II promoter  glutathione metabolic process  methylglyoxal metabolic process  negative regulation of apoptotic process  negative regulation of apoptotic process  negative regulation of apoptotic process  metal ion binding  
Pathways : KEGGPyruvate metabolism
Other databases
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
PubGeneGLO1
iHOPGLO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:26:02 CEST 2013
Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.