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GNA14 (G protein subunit alpha 14)

Identity

Alias_namesguanine nucleotide binding protein (G protein)
Other alias-
HGNC (Hugo) GNA14
LocusID (NCBI) 9630
Atlas_Id 43274
Location 9q21.2  [Link to chromosome band 9q21]
Location_base_pair Starts at 77423079 and ends at 77648316 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DIRAS2 (9q22.2) / GNA14 (9q21.2)GNA14 (9q21.2) / TRMO (9q22.33)RC3H2 (9q33.2) / GNA14 (9q21.2)
SDS (12q24.13) / GNA14 (9q21.2)TDRD7 (9q22.33) / GNA14 (9q21.2)DIRAS2 9q22.2 / GNA14 9q21.2
GNA14 9q21.2 / C9orf156 9q22.33RC3H2 9q33.2 / GNA14 9q21.2TDRD7 9q22.33 / GNA14 9q21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GNA14   4382
Cards
Entrez_Gene (NCBI)GNA14  9630  G protein subunit alpha 14
Aliases
GeneCards (Weizmann)GNA14
Ensembl hg19 (Hinxton)ENSG00000156049 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156049 [Gene_View]  chr9:77423079-77648316 [Contig_View]  GNA14 [Vega]
ICGC DataPortalENSG00000156049
TCGA cBioPortalGNA14
AceView (NCBI)GNA14
Genatlas (Paris)GNA14
WikiGenes9630
SOURCE (Princeton)GNA14
Genetics Home Reference (NIH)GNA14
Genomic and cartography
GoldenPath hg38 (UCSC)GNA14  -     chr9:77423079-77648316 -  9q21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GNA14  -     9q21.2   [Description]    (hg19-Feb_2009)
EnsemblGNA14 - 9q21.2 [CytoView hg19]  GNA14 - 9q21.2 [CytoView hg38]
Mapping of homologs : NCBIGNA14 [Mapview hg19]  GNA14 [Mapview hg38]
OMIM604397   
Gene and transcription
Genbank (Entrez)AF105201 AF493903 AI263118 AI629022 AK312460
RefSeq transcript (Entrez)NM_004297
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GNA14
Cluster EST : UnigeneHs.657795 [ NCBI ]
CGAP (NCI)Hs.657795
Alternative Splicing GalleryENSG00000156049
Gene ExpressionGNA14 [ NCBI-GEO ]   GNA14 [ EBI - ARRAY_EXPRESS ]   GNA14 [ SEEK ]   GNA14 [ MEM ]
Gene Expression Viewer (FireBrowse)GNA14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9630
GTEX Portal (Tissue expression)GNA14
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95837   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95837  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95837
Splice isoforms : SwissVarO95837
PhosPhoSitePlusO95837
Domains : Interpro (EBI)Gprotein_alpha_Q    Gprotein_alpha_su    GproteinA_insert    P-loop_NTPase   
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
Conserved Domain (NCBI)GNA14
DMDM Disease mutations9630
Blocks (Seattle)GNA14
SuperfamilyO95837
Human Protein AtlasENSG00000156049
Peptide AtlasO95837
HPRD05095
IPIIPI00000695   
Protein Interaction databases
DIP (DOE-UCLA)O95837
IntAct (EBI)O95837
FunCoupENSG00000156049
BioGRIDGNA14
STRING (EMBL)GNA14
ZODIACGNA14
Ontologies - Pathways
QuickGOO95837
Ontology : AmiGOG-protein coupled receptor binding  GTPase activity  GTPase activity  signal transducer activity  protein binding  GTP binding  heterotrimeric G-protein complex  plasma membrane  signal transduction  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  platelet activation  G-protein beta/gamma-subunit complex binding  metal ion binding  phospholipase C-activating dopamine receptor signaling pathway  extracellular exosome  
Ontology : EGO-EBIG-protein coupled receptor binding  GTPase activity  GTPase activity  signal transducer activity  protein binding  GTP binding  heterotrimeric G-protein complex  plasma membrane  signal transduction  adenylate cyclase-modulating G-protein coupled receptor signaling pathway  platelet activation  G-protein beta/gamma-subunit complex binding  metal ion binding  phospholipase C-activating dopamine receptor signaling pathway  extracellular exosome  
Pathways : KEGGCalcium signaling pathway    Chagas disease (American trypanosomiasis)    Amoebiasis   
NDEx NetworkGNA14
Atlas of Cancer Signalling NetworkGNA14
Wikipedia pathwaysGNA14
Orthology - Evolution
OrthoDB9630
GeneTree (enSembl)ENSG00000156049
Phylogenetic Trees/Animal Genes : TreeFamGNA14
HOVERGENO95837
HOGENOMO95837
Homologs : HomoloGeneGNA14
Homology/Alignments : Family Browser (UCSC)GNA14
Gene fusions - Rearrangements
Fusion : MitelmanDIRAS2/GNA14 [9q22.2/9q21.2]  [t(9;9)(q21;q22)]  
Fusion : MitelmanGNA14/C9orf156 [9q21.2/9q22.33]  [t(9;9)(q21;q22)]  
Fusion : MitelmanRC3H2/GNA14 [9q33.2/9q21.2]  [t(9;9)(q21;q33)]  
Fusion : MitelmanTDRD7/GNA14 [9q22.33/9q21.2]  [t(9;9)(q21;q22)]  
Fusion: TCGADIRAS2 9q22.2 GNA14 9q21.2 BLCA
Fusion: TCGAGNA14 9q21.2 C9orf156 9q22.33 BRCA
Fusion: TCGARC3H2 9q33.2 GNA14 9q21.2 BRCA
Fusion: TCGATDRD7 9q22.33 GNA14 9q21.2 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGNA14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GNA14
dbVarGNA14
ClinVarGNA14
1000_GenomesGNA14 
Exome Variant ServerGNA14
ExAC (Exome Aggregation Consortium)GNA14 (select the gene name)
Genetic variants : HAPMAP9630
Genomic Variants (DGV)GNA14 [DGVbeta]
DECIPHERGNA14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGNA14 
Mutations
ICGC Data PortalGNA14 
TCGA Data PortalGNA14 
Broad Tumor PortalGNA14
OASIS PortalGNA14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGNA14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGNA14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GNA14
DgiDB (Drug Gene Interaction Database)GNA14
DoCM (Curated mutations)GNA14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GNA14 (select a term)
intoGenGNA14
Cancer3DGNA14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604397   
Orphanet
MedgenGNA14
Genetic Testing Registry GNA14
NextProtO95837 [Medical]
TSGene9630
GENETestsGNA14
Target ValidationGNA14
Huge Navigator GNA14 [HugePedia]
snp3D : Map Gene to Disease9630
BioCentury BCIQGNA14
ClinGenGNA14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9630
Chemical/Pharm GKB GenePA28767
Clinical trialGNA14
Miscellaneous
canSAR (ICR)GNA14 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGNA14
EVEXGNA14
GoPubMedGNA14
iHOPGNA14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:10:04 CEST 2017

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