Atlas of Genetics and Cytogenetics in Oncology and Haematology

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GNAI2 (guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2)

Identity

Other namesGIP
GNAI2B
H_LUCA15.1
H_LUCA16.1
HGNC (Hugo) GNAI2
LocusID (NCBI) 2771
Location 3p21.31
Location_base_pair Starts at 50284326 and ends at 50296786 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)GNAI2   4385
Entrez_Gene (NCBI)GNAI2  2771  guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Cards
GeneCards (Weizmann)GNAI2
Ensembl (Hinxton)ENSG00000114353 [Gene_View]  chr3:50284326-50296786 [Contig_View]  GNAI2 [Vega]
AceView (NCBI)GNAI2
Genatlas (Paris)GNAI2
SOURCE (Stanford)NM_001166425 NM_002070
Genomic and cartography
GoldenPath (UCSC)GNAI2  -  3p21.31   chr3:50284326-50296786 +  3p21.31   [Description]    (hg19-Feb_2009)
EnsemblGNAI2 - 3p21.31 [CytoView]
Mapping of homologs : NCBIGNAI2 [Mapview]
OMIM139360   192605   
Gene and transcription
Genbank (Entrez)AF493906 AK055574 AK096299 AK096595 AK126708
RefSeq transcript (SRS)NM_001166425 NM_002070
RefSeq transcript (Entrez)NM_001166425 NM_002070
RefSeq genomic (SRS)AC_000135 NC_000003 NC_018914 NG_016002 NT_022517 NW_001838877 NW_003871059 NW_004078011
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_016002 NT_022517 NW_001838877 NW_003871059 NW_004078011
Consensus coding sequences : CCDS (NCBI)GNAI2
Cluster EST : UnigeneHs.77269 [ SRS ] Hs.77269 [ NCBI ]
CGAP (NCI)Hs.77269
Alternative Splicing : Fast-db (Paris)GSHG0020817
Alternative Splicing GalleryENSG00000114353
Gene ExpressionGNAI2 [ NCBI-GEO ]   GNAI2 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP04899 (SRS) P04899 (Uniprot)
NextProtP04899
With graphics : InterProP04899
Splice isoforms : SwissVarP04899(Swissvar)
Domains : Interpro (SRS)Gprotein_alpha_I    Gprotein_alpha_su    GproteinA_insert   
Domains : Interpro (EBI)Gprotein_alpha_I    Gprotein_alpha_su    GproteinA_insert   
Related proteins : CluSTrP04899
Domain families : Pfam (SRS)G-alpha (PF00503)   
Domain families : Pfam (Sanger)G-alpha (PF00503)   
Domain families : Pfam (NCBI)pfam00503   
Domain families : Smart (EMBL)G_alpha (SM00275)  
DMDM2771
Blocks (Seattle)P04899
Human Protein AtlasENSG00000114353
HPRD00764
IPIIPI00748145   IPI00217906   IPI00926935   IPI01015661   IPI00925504   IPI00924892   IPI00924659   IPI00924427   
Protein Interaction databases
DIP (DOE-UCLA)P04899
IntAct (EBI)P04899
FunCoupENSG00000114353
REACTOMEGNAI2
Protein Interaction Database2771
BioGRIDGNAI2
InParanoidP04899
Interologous Interaction database P04899
IntegromeDBGNAI2
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)GNAI2
SNP (GeneSNP Utah)GNAI2
SNP : HGBaseGNAI2
Genetic variants : HAPMAPGNAI2
Somatic Mutations in Cancer : COSMICGNAI2 
CONAN: Copy Number AnalysisGNAI2 
Mutations and Diseases : HGMDGNAI2
OMIM139360    192605   
GENETests139360    192605   
Disease Genetic AssociationGNAI2
Huge Navigator GNAI2 [HugePedia]  GNAI2 [HugeCancerGEM]
Genomic VariantsGNAI2  GNAI2 [DGVbeta]
snp3D : Map Gene to Disease2771
General knowledge
Homologs : HomoloGeneGNAI2
Homology/Alignments : Family Browser (UCSC)GNAI2
Phylogenetic Trees/Animal Genes : TreeFamGNAI2
Chemical/Protein Interactions : CTD2771
Chemical/Pharm GKB GenePA24347
Clinical trialGNAI2
Cancer Resource (Charite)ENSG00000114353
Ontology : AmiGOactivation of MAPKK activity  G-protein coupled receptor binding  adenosine receptor signaling pathway  GTPase activity  signal transducer activity  protein binding  GTP binding  nucleus  cytoplasm  centrosome  cytosol  heterotrimeric G-protein complex  plasma membrane  plasma membrane  GTP catabolic process  GTP catabolic process  cell cycle  signal transduction  G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  G-protein coupled acetylcholine receptor signaling pathway  gamma-aminobutyric acid signaling pathway  intracellular protein kinase cascade  synaptic transmission  response to nutrient  blood coagulation  cell proliferation  positive regulation of cell proliferation  platelet activation  midbody  extrinsic to internal side of plasma membrane  G-protein beta/gamma-subunit complex binding  membrane raft  metal ion binding  negative regulation of synaptic transmission  cell division  
Ontology : EGO-EBIactivation of MAPKK activity  G-protein coupled receptor binding  adenosine receptor signaling pathway  GTPase activity  signal transducer activity  protein binding  GTP binding  nucleus  cytoplasm  centrosome  cytosol  heterotrimeric G-protein complex  plasma membrane  plasma membrane  GTP catabolic process  GTP catabolic process  cell cycle  signal transduction  G-protein coupled receptor signaling pathway  adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway  negative regulation of adenylate cyclase activity  G-protein coupled acetylcholine receptor signaling pathway  gamma-aminobutyric acid signaling pathway  intracellular protein kinase cascade  synaptic transmission  response to nutrient  blood coagulation  cell proliferation  positive regulation of cell proliferation  platelet activation  midbody  extrinsic to internal side of plasma membrane  G-protein beta/gamma-subunit complex binding  membrane raft  metal ion binding  negative regulation of synaptic transmission  cell division  
Pathways : KEGGTight junctionAxon guidanceLong-term depressionLeukocyte transendothelial migrationGap junction
Other databases
Probes
Litterature
PubMed119 Pubmed reference(s) in Entrez
PubGeneGNAI2
iHOPGNAI2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:49:00 CEST 2013
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