Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GPBAR1 (G protein-coupled bile acid receptor 1)

Identity

Alias_symbol (synonym)BG37
GPCR
TGR5
M-BAR
GPCR19
GPR131
MGC40597
Other alias
HGNC (Hugo) GPBAR1
LocusID (NCBI) 151306
Atlas_Id 46065
Location 2q35  [Link to chromosome band 2q35]
Location_base_pair Starts at 219125738 and ends at 219128582 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
FMNL2 (2q23.3) / GPBAR1 (2q35)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GPBAR1   19680
Cards
Entrez_Gene (NCBI)GPBAR1  151306  G protein-coupled bile acid receptor 1
AliasesBG37; GPCR19; GPR131; M-BAR; 
TGR5
GeneCards (Weizmann)GPBAR1
Ensembl hg19 (Hinxton)ENSG00000179921 [Gene_View]  chr2:219125738-219128582 [Contig_View]  GPBAR1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000179921 [Gene_View]  chr2:219125738-219128582 [Contig_View]  GPBAR1 [Vega]
ICGC DataPortalENSG00000179921
TCGA cBioPortalGPBAR1
AceView (NCBI)GPBAR1
Genatlas (Paris)GPBAR1
WikiGenes151306
SOURCE (Princeton)GPBAR1
Genetics Home Reference (NIH)GPBAR1
Genomic and cartography
GoldenPath hg19 (UCSC)GPBAR1  -     chr2:219125738-219128582 +  2q35   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GPBAR1  -     2q35   [Description]    (hg38-Dec_2013)
EnsemblGPBAR1 - 2q35 [CytoView hg19]  GPBAR1 - 2q35 [CytoView hg38]
Mapping of homologs : NCBIGPBAR1 [Mapview hg19]  GPBAR1 [Mapview hg38]
OMIM610147   
Gene and transcription
Genbank (Entrez)AB086170 AB089307 AK122658 AK122660 BC033625
RefSeq transcript (Entrez)NM_001077191 NM_001077194 NM_001321950 NM_170699
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)GPBAR1
Cluster EST : UnigeneHs.160954 [ NCBI ]
CGAP (NCI)Hs.160954
Alternative Splicing GalleryENSG00000179921
Gene ExpressionGPBAR1 [ NCBI-GEO ]   GPBAR1 [ EBI - ARRAY_EXPRESS ]   GPBAR1 [ SEEK ]   GPBAR1 [ MEM ]
Gene Expression Viewer (FireBrowse)GPBAR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)151306
GTEX Portal (Tissue expression)GPBAR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TDU6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TDU6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TDU6
Splice isoforms : SwissVarQ8TDU6
PhosPhoSitePlusQ8TDU6
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)GPBAR1
DMDM Disease mutations151306
Blocks (Seattle)GPBAR1
SuperfamilyQ8TDU6
Human Protein AtlasENSG00000179921
Peptide AtlasQ8TDU6
HPRD17050
IPIIPI00152620   
Protein Interaction databases
DIP (DOE-UCLA)Q8TDU6
IntAct (EBI)Q8TDU6
FunCoupENSG00000179921
BioGRIDGPBAR1
STRING (EMBL)GPBAR1
ZODIACGPBAR1
Ontologies - Pathways
QuickGOQ8TDU6
Ontology : AmiGOcytoplasm  plasma membrane  plasma membrane  G-protein coupled receptor signaling pathway  integral component of membrane  bile acid receptor activity  G-protein coupled bile acid receptor activity  cell surface bile acid receptor signaling pathway  regulation of bicellular tight junction assembly  
Ontology : EGO-EBIcytoplasm  plasma membrane  plasma membrane  G-protein coupled receptor signaling pathway  integral component of membrane  bile acid receptor activity  G-protein coupled bile acid receptor activity  cell surface bile acid receptor signaling pathway  regulation of bicellular tight junction assembly  
NDEx NetworkGPBAR1
Atlas of Cancer Signalling NetworkGPBAR1
Wikipedia pathwaysGPBAR1
Orthology - Evolution
OrthoDB151306
GeneTree (enSembl)ENSG00000179921
Phylogenetic Trees/Animal Genes : TreeFamGPBAR1
HOVERGENQ8TDU6
HOGENOMQ8TDU6
Homologs : HomoloGeneGPBAR1
Homology/Alignments : Family Browser (UCSC)GPBAR1
Gene fusions - Rearrangements
Fusion : MitelmanFMNL2/GPBAR1 [2q23.3/2q35]  [del(2)(q23q35)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGPBAR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GPBAR1
dbVarGPBAR1
ClinVarGPBAR1
1000_GenomesGPBAR1 
Exome Variant ServerGPBAR1
ExAC (Exome Aggregation Consortium)GPBAR1 (select the gene name)
Genetic variants : HAPMAP151306
Genomic Variants (DGV)GPBAR1 [DGVbeta]
DECIPHER (Syndromes)2:219125738-219128582  ENSG00000179921
CONAN: Copy Number AnalysisGPBAR1 
Mutations
ICGC Data PortalGPBAR1 
TCGA Data PortalGPBAR1 
Broad Tumor PortalGPBAR1
OASIS PortalGPBAR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGPBAR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGPBAR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GPBAR1
DgiDB (Drug Gene Interaction Database)GPBAR1
DoCM (Curated mutations)GPBAR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GPBAR1 (select a term)
intoGenGPBAR1
Cancer3DGPBAR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610147   
Orphanet
MedgenGPBAR1
Genetic Testing Registry GPBAR1
NextProtQ8TDU6 [Medical]
TSGene151306
GENETestsGPBAR1
Huge Navigator GPBAR1 [HugePedia]
snp3D : Map Gene to Disease151306
BioCentury BCIQGPBAR1
ClinGenGPBAR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD151306
Chemical/Pharm GKB GenePA134903170
Clinical trialGPBAR1
Miscellaneous
canSAR (ICR)GPBAR1 (select the gene name)
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGPBAR1
EVEXGPBAR1
GoPubMedGPBAR1
iHOPGPBAR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:02:49 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.