Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GRB14 (growth factor receptor bound protein 14)

Identity

Alias_namesgrowth factor receptor-bound protein 14
Other alias-
HGNC (Hugo) GRB14
LocusID (NCBI) 2888
Atlas_Id 40749
Location 2q24.3  [Link to chromosome band 2q24]
Location_base_pair Starts at 165348916 and ends at 165425060 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GRB14 (2q24.3) / GRB14 (2q24.3)GRB14 (2q24.3) / IFIH1 (2q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GRB14   4565
Cards
Entrez_Gene (NCBI)GRB14  2888  growth factor receptor bound protein 14
Aliases
GeneCards (Weizmann)GRB14
Ensembl hg19 (Hinxton)ENSG00000115290 [Gene_View]  chr2:165348916-165425060 [Contig_View]  GRB14 [Vega]
Ensembl hg38 (Hinxton)ENSG00000115290 [Gene_View]  chr2:165348916-165425060 [Contig_View]  GRB14 [Vega]
ICGC DataPortalENSG00000115290
TCGA cBioPortalGRB14
AceView (NCBI)GRB14
Genatlas (Paris)GRB14
WikiGenes2888
SOURCE (Princeton)GRB14
Genetics Home Reference (NIH)GRB14
Genomic and cartography
GoldenPath hg19 (UCSC)GRB14  -     chr2:165348916-165425060 -  2q24.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GRB14  -     2q24.3   [Description]    (hg38-Dec_2013)
EnsemblGRB14 - 2q24.3 [CytoView hg19]  GRB14 - 2q24.3 [CytoView hg38]
Mapping of homologs : NCBIGRB14 [Mapview hg19]  GRB14 [Mapview hg38]
OMIM601524   
Gene and transcription
Genbank (Entrez)AK301961 AK302129 AK307744 AK309590 AK313153
RefSeq transcript (Entrez)NM_001303422 NM_004490
RefSeq genomic (Entrez)NC_000002 NC_018913 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)GRB14
Cluster EST : UnigeneHs.411881 [ NCBI ]
CGAP (NCI)Hs.411881
Alternative Splicing GalleryENSG00000115290
Gene ExpressionGRB14 [ NCBI-GEO ]   GRB14 [ EBI - ARRAY_EXPRESS ]   GRB14 [ SEEK ]   GRB14 [ MEM ]
Gene Expression Viewer (FireBrowse)GRB14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2888
GTEX Portal (Tissue expression)GRB14
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14449   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14449  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14449
Splice isoforms : SwissVarQ14449
PhosPhoSitePlusQ14449
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    RA (PS50200)    SH2 (PS50001)   
Domains : Interpro (EBI)BPS-dom    PH_dom-like    PH_domain    RA_dom    SH2    Ubiquitin-rel_dom   
Domain families : Pfam (Sanger)BPS (PF08947)    PH (PF00169)    RA (PF00788)    SH2 (PF00017)   
Domain families : Pfam (NCBI)pfam08947    pfam00169    pfam00788    pfam00017   
Domain families : Smart (EMBL)PH (SM00233)  RA (SM00314)  SH2 (SM00252)  
Conserved Domain (NCBI)GRB14
DMDM Disease mutations2888
Blocks (Seattle)GRB14
PDB (SRS)2AUG    2AUH    4K81   
PDB (PDBSum)2AUG    2AUH    4K81   
PDB (IMB)2AUG    2AUH    4K81   
PDB (RSDB)2AUG    2AUH    4K81   
Structural Biology KnowledgeBase2AUG    2AUH    4K81   
SCOP (Structural Classification of Proteins)2AUG    2AUH    4K81   
CATH (Classification of proteins structures)2AUG    2AUH    4K81   
SuperfamilyQ14449
Human Protein AtlasENSG00000115290
Peptide AtlasQ14449
HPRD03313
IPIIPI00030917   IPI00922085   IPI00917717   IPI00916793   
Protein Interaction databases
DIP (DOE-UCLA)Q14449
IntAct (EBI)Q14449
FunCoupENSG00000115290
BioGRIDGRB14
STRING (EMBL)GRB14
ZODIACGRB14
Ontologies - Pathways
QuickGOQ14449
Ontology : AmiGOSH3/SH2 adaptor activity  cytoplasm  cytosol  plasma membrane  signal transduction  positive regulation of signal transduction  endosome membrane  intracellular membrane-bounded organelle  leukocyte migration  
Ontology : EGO-EBISH3/SH2 adaptor activity  cytoplasm  cytosol  plasma membrane  signal transduction  positive regulation of signal transduction  endosome membrane  intracellular membrane-bounded organelle  leukocyte migration  
NDEx NetworkGRB14
Atlas of Cancer Signalling NetworkGRB14
Wikipedia pathwaysGRB14
Orthology - Evolution
OrthoDB2888
GeneTree (enSembl)ENSG00000115290
Phylogenetic Trees/Animal Genes : TreeFamGRB14
HOVERGENQ14449
HOGENOMQ14449
Homologs : HomoloGeneGRB14
Homology/Alignments : Family Browser (UCSC)GRB14
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGRB14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GRB14
dbVarGRB14
ClinVarGRB14
1000_GenomesGRB14 
Exome Variant ServerGRB14
ExAC (Exome Aggregation Consortium)GRB14 (select the gene name)
Genetic variants : HAPMAP2888
Genomic Variants (DGV)GRB14 [DGVbeta]
DECIPHER (Syndromes)2:165348916-165425060  ENSG00000115290
CONAN: Copy Number AnalysisGRB14 
Mutations
ICGC Data PortalGRB14 
TCGA Data PortalGRB14 
Broad Tumor PortalGRB14
OASIS PortalGRB14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGRB14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGRB14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GRB14
DgiDB (Drug Gene Interaction Database)GRB14
DoCM (Curated mutations)GRB14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GRB14 (select a term)
intoGenGRB14
Cancer3DGRB14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601524   
Orphanet
MedgenGRB14
Genetic Testing Registry GRB14
NextProtQ14449 [Medical]
TSGene2888
GENETestsGRB14
Huge Navigator GRB14 [HugePedia]
snp3D : Map Gene to Disease2888
BioCentury BCIQGRB14
ClinGenGRB14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2888
Chemical/Pharm GKB GenePA28961
Clinical trialGRB14
Miscellaneous
canSAR (ICR)GRB14 (select the gene name)
Probes
Litterature
PubMed46 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGRB14
EVEXGRB14
GoPubMedGRB14
iHOPGRB14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 30 15:03:00 CEST 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.