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GSTA2 (glutathione S-transferase alpha 2)

Identity

Alias_namesGST2
glutathione S-transferase A2
Other aliasGSTA2-2
GTA2
GTH2
HGNC (Hugo) GSTA2
LocusID (NCBI) 2939
Atlas_Id 40765
Location 6p12.2  [Link to chromosome band 6p12]
Location_base_pair Starts at 52750087 and ends at 52763563 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSTA2   4627
Cards
Entrez_Gene (NCBI)GSTA2  2939  glutathione S-transferase alpha 2
AliasesGST2; GSTA2-2; GTA2; GTH2
GeneCards (Weizmann)GSTA2
Ensembl hg19 (Hinxton)ENSG00000244067 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000244067 [Gene_View]  ENSG00000244067 [Sequence]  chr6:52750087-52763563 [Contig_View]  GSTA2 [Vega]
ICGC DataPortalENSG00000244067
TCGA cBioPortalGSTA2
AceView (NCBI)GSTA2
Genatlas (Paris)GSTA2
WikiGenes2939
SOURCE (Princeton)GSTA2
Genetics Home Reference (NIH)GSTA2
Genomic and cartography
GoldenPath hg38 (UCSC)GSTA2  -     chr6:52750087-52763563 -  6p12.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSTA2  -     6p12.2   [Description]    (hg19-Feb_2009)
EnsemblGSTA2 - 6p12.2 [CytoView hg19]  GSTA2 - 6p12.2 [CytoView hg38]
Mapping of homologs : NCBIGSTA2 [Mapview hg19]  GSTA2 [Mapview hg38]
OMIM138360   
Gene and transcription
Genbank (Entrez)AK292602 AK313601 BC002895 BE795593 BE796134
RefSeq transcript (Entrez)NM_000846
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GSTA2
Cluster EST : UnigeneHs.94107 [ NCBI ]
CGAP (NCI)Hs.94107
Alternative Splicing GalleryENSG00000244067
Gene ExpressionGSTA2 [ NCBI-GEO ]   GSTA2 [ EBI - ARRAY_EXPRESS ]   GSTA2 [ SEEK ]   GSTA2 [ MEM ]
Gene Expression Viewer (FireBrowse)GSTA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2939
GTEX Portal (Tissue expression)GSTA2
Human Protein AtlasENSG00000244067-GSTA2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09210   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09210  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09210
Splice isoforms : SwissVarP09210
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
PhosPhoSitePlusP09210
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione-S-Trfase_C_sf    Glutathione_S-Trfase_N    GST_alpha    GST_C    Thioredoxin-like_sf   
Domain families : Pfam (Sanger)GST_C_3 (PF14497)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam14497    pfam02798   
Conserved Domain (NCBI)GSTA2
DMDM Disease mutations2939
Blocks (Seattle)GSTA2
PDB (SRS)1AGS    2VCT    2WJU    4ACS   
PDB (PDBSum)1AGS    2VCT    2WJU    4ACS   
PDB (IMB)1AGS    2VCT    2WJU    4ACS   
PDB (RSDB)1AGS    2VCT    2WJU    4ACS   
Structural Biology KnowledgeBase1AGS    2VCT    2WJU    4ACS   
SCOP (Structural Classification of Proteins)1AGS    2VCT    2WJU    4ACS   
CATH (Classification of proteins structures)1AGS    2VCT    2WJU    4ACS   
SuperfamilyP09210
Human Protein Atlas [tissue]ENSG00000244067-GSTA2 [tissue]
Peptide AtlasP09210
HPRD00709
IPIIPI00745233   IPI01025265   IPI01025209   
Protein Interaction databases
DIP (DOE-UCLA)P09210
IntAct (EBI)P09210
FunCoupENSG00000244067
BioGRIDGSTA2
STRING (EMBL)GSTA2
ZODIACGSTA2
Ontologies - Pathways
QuickGOP09210
Ontology : AmiGOglutathione transferase activity  glutathione transferase activity  protein binding  cytosol  cytosol  glutathione metabolic process  epithelial cell differentiation  interleukin-12-mediated signaling pathway  extracellular exosome  extracellular exosome  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  glutathione transferase activity  protein binding  cytosol  cytosol  glutathione metabolic process  epithelial cell differentiation  interleukin-12-mediated signaling pathway  extracellular exosome  extracellular exosome  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkGSTA2
Atlas of Cancer Signalling NetworkGSTA2
Wikipedia pathwaysGSTA2
Orthology - Evolution
OrthoDB2939
GeneTree (enSembl)ENSG00000244067
Phylogenetic Trees/Animal Genes : TreeFamGSTA2
HOVERGENP09210
HOGENOMP09210
Homologs : HomoloGeneGSTA2
Homology/Alignments : Family Browser (UCSC)GSTA2
Gene fusions - Rearrangements
Fusion : QuiverGSTA2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSTA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTA2
dbVarGSTA2
ClinVarGSTA2
1000_GenomesGSTA2 
Exome Variant ServerGSTA2
ExAC (Exome Aggregation Consortium)ENSG00000244067
GNOMAD BrowserENSG00000244067
Varsome BrowserGSTA2
Genetic variants : HAPMAP2939
Genomic Variants (DGV)GSTA2 [DGVbeta]
DECIPHERGSTA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSTA2 
Mutations
ICGC Data PortalGSTA2 
TCGA Data PortalGSTA2 
Broad Tumor PortalGSTA2
OASIS PortalGSTA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSTA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSTA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GSTA2
DgiDB (Drug Gene Interaction Database)GSTA2
DoCM (Curated mutations)GSTA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSTA2 (select a term)
intoGenGSTA2
Cancer3DGSTA2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM138360   
Orphanet
DisGeNETGSTA2
MedgenGSTA2
Genetic Testing Registry GSTA2
NextProtP09210 [Medical]
TSGene2939
GENETestsGSTA2
Target ValidationGSTA2
Huge Navigator GSTA2 [HugePedia]
snp3D : Map Gene to Disease2939
BioCentury BCIQGSTA2
ClinGenGSTA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2939
Chemical/Pharm GKB GenePA29017
Clinical trialGSTA2
Miscellaneous
canSAR (ICR)GSTA2 (select the gene name)
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSTA2
EVEXGSTA2
GoPubMedGSTA2
iHOPGSTA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:09:45 CET 2018

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