Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

GSTM3 (glutathione S-transferase mu 3)

Identity

Alias_namesglutathione S-transferase M3 (brain)
glutathione S-transferase mu 3 (brain)
Alias_symbol (synonym)GST5
Other aliasGSTB
GSTM3-3
GTM3
HGNC (Hugo) GSTM3
LocusID (NCBI) 2947
Atlas_Id 40770
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 109733932 and ends at 109741038 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IQSEC1 (3p25.2) / GSTM3 (1p13.3)IQSEC1 3p25.2 / GSTM3 1p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSTM3   4635
Cards
Entrez_Gene (NCBI)GSTM3  2947  glutathione S-transferase mu 3
AliasesGST5; GSTB; GSTM3-3; GTM3
GeneCards (Weizmann)GSTM3
Ensembl hg19 (Hinxton)ENSG00000134202 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134202 [Gene_View]  chr1:109733932-109741038 [Contig_View]  GSTM3 [Vega]
ICGC DataPortalENSG00000134202
TCGA cBioPortalGSTM3
AceView (NCBI)GSTM3
Genatlas (Paris)GSTM3
WikiGenes2947
SOURCE (Princeton)GSTM3
Genetics Home Reference (NIH)GSTM3
Genomic and cartography
GoldenPath hg38 (UCSC)GSTM3  -     chr1:109733932-109741038 -  1p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)GSTM3  -     1p13.3   [Description]    (hg19-Feb_2009)
EnsemblGSTM3 - 1p13.3 [CytoView hg19]  GSTM3 - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBIGSTM3 [Mapview hg19]  GSTM3 [Mapview hg38]
OMIM138390   
Gene and transcription
Genbank (Entrez)AB209816 AI201498 AI570401 AK304300 AK313444
RefSeq transcript (Entrez)NM_000849
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)GSTM3
Cluster EST : UnigeneHs.2006 [ NCBI ]
CGAP (NCI)Hs.2006
Alternative Splicing GalleryENSG00000134202
Gene ExpressionGSTM3 [ NCBI-GEO ]   GSTM3 [ EBI - ARRAY_EXPRESS ]   GSTM3 [ SEEK ]   GSTM3 [ MEM ]
Gene Expression Viewer (FireBrowse)GSTM3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2947
GTEX Portal (Tissue expression)GSTM3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP21266   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP21266  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP21266
Splice isoforms : SwissVarP21266
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
PhosPhoSitePlusP21266
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    GST_C    GST_mu    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)GST_C (PF00043)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam00043    pfam02798   
Conserved Domain (NCBI)GSTM3
DMDM Disease mutations2947
Blocks (Seattle)GSTM3
PDB (SRS)3GTU   
PDB (PDBSum)3GTU   
PDB (IMB)3GTU   
PDB (RSDB)3GTU   
Structural Biology KnowledgeBase3GTU   
SCOP (Structural Classification of Proteins)3GTU   
CATH (Classification of proteins structures)3GTU   
SuperfamilyP21266
Human Protein AtlasENSG00000134202
Peptide AtlasP21266
HPRD00712
IPIIPI00246975   IPI00845493   
Protein Interaction databases
DIP (DOE-UCLA)P21266
IntAct (EBI)P21266
FunCoupENSG00000134202
BioGRIDGSTM3
STRING (EMBL)GSTM3
ZODIACGSTM3
Ontologies - Pathways
QuickGOP21266
Ontology : AmiGOglutathione transferase activity  glutathione transferase activity  nucleus  cytoplasm  cytosol  glutathione metabolic process  establishment of blood-nerve barrier  nitrobenzene metabolic process  enzyme binding  sperm fibrous sheath  xenobiotic catabolic process  identical protein binding  protein homodimerization activity  protein homodimerization activity  glutathione binding  response to estrogen  extracellular exosome  cellular detoxification of nitrogen compound  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  glutathione transferase activity  nucleus  cytoplasm  cytosol  glutathione metabolic process  establishment of blood-nerve barrier  nitrobenzene metabolic process  enzyme binding  sperm fibrous sheath  xenobiotic catabolic process  identical protein binding  protein homodimerization activity  protein homodimerization activity  glutathione binding  response to estrogen  extracellular exosome  cellular detoxification of nitrogen compound  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkGSTM3
Atlas of Cancer Signalling NetworkGSTM3
Wikipedia pathwaysGSTM3
Orthology - Evolution
OrthoDB2947
GeneTree (enSembl)ENSG00000134202
Phylogenetic Trees/Animal Genes : TreeFamGSTM3
HOVERGENP21266
HOGENOMP21266
Homologs : HomoloGeneGSTM3
Homology/Alignments : Family Browser (UCSC)GSTM3
Gene fusions - Rearrangements
Fusion : MitelmanIQSEC1/GSTM3 [3p25.2/1p13.3]  [t(1;3)(p13;p25)]  
Fusion: TCGAIQSEC1 3p25.2 GSTM3 1p13.3 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSTM3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTM3
dbVarGSTM3
ClinVarGSTM3
1000_GenomesGSTM3 
Exome Variant ServerGSTM3
ExAC (Exome Aggregation Consortium)GSTM3 (select the gene name)
Genetic variants : HAPMAP2947
Genomic Variants (DGV)GSTM3 [DGVbeta]
DECIPHERGSTM3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisGSTM3 
Mutations
ICGC Data PortalGSTM3 
TCGA Data PortalGSTM3 
Broad Tumor PortalGSTM3
OASIS PortalGSTM3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSTM3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSTM3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch GSTM3
DgiDB (Drug Gene Interaction Database)GSTM3
DoCM (Curated mutations)GSTM3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSTM3 (select a term)
intoGenGSTM3
Cancer3DGSTM3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM138390   
Orphanet
MedgenGSTM3
Genetic Testing Registry GSTM3
NextProtP21266 [Medical]
TSGene2947
GENETestsGSTM3
Target ValidationGSTM3
Huge Navigator GSTM3 [HugePedia]
snp3D : Map Gene to Disease2947
BioCentury BCIQGSTM3
ClinGenGSTM3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2947
Chemical/Pharm GKB GenePA29024
Clinical trialGSTM3
Miscellaneous
canSAR (ICR)GSTM3 (select the gene name)
Probes
Litterature
PubMed154 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSTM3
EVEXGSTM3
GoPubMedGSTM3
iHOPGSTM3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:36:08 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.