Atlas of Genetics and Cytogenetics in Oncology and Haematology


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GSTT1 (glutathione S-transferase theta 1)

Identity

Other alias-
HGNC (Hugo) GSTT1
LocusID (NCBI) 2952
Atlas_Id 40774
Location 22q11.23  [Link to chromosome band 22q11]
Location_base_pair Starts at 24376133 and ends at 24384311 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GSTT1 (22q11.23) / SLC2A11 (22q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)GSTT1   4641
Cards
Entrez_Gene (NCBI)GSTT1  2952  glutathione S-transferase theta 1
Aliases
GeneCards (Weizmann)GSTT1
Ensembl hg19 (Hinxton) [Gene_View]  chr22:24376133-24384311 [Contig_View]  GSTT1 [Vega]
Ensembl hg38 (Hinxton) [Gene_View]  chr22:24376133-24384311 [Contig_View]  GSTT1 [Vega]
TCGA cBioPortalGSTT1
AceView (NCBI)GSTT1
Genatlas (Paris)GSTT1
WikiGenes2952
SOURCE (Princeton)GSTT1
Genetics Home Reference (NIH)GSTT1
Genomic and cartography
GoldenPath hg19 (UCSC)GSTT1  -     chr22:24376133-24384311 -  22q11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)GSTT1  -     22q11.23   [Description]    (hg38-Dec_2013)
EnsemblGSTT1 - 22q11.23 [CytoView hg19]  GSTT1 - 22q11.23 [CytoView hg38]
Mapping of homologs : NCBIGSTT1 [Mapview hg19]  GSTT1 [Mapview hg38]
OMIM600436   
Gene and transcription
Genbank (Entrez)AA298437 AF435971 AJ867757 AJ867758 AJ874719
RefSeq transcript (Entrez)NM_000853 NM_001293807 NM_001293808 NM_001293809 NM_001293810 NM_001293811 NM_001293812 NM_001293813 NM_001293814
RefSeq genomic (Entrez)NT_187633
Consensus coding sequences : CCDS (NCBI)GSTT1
Cluster EST : UnigeneHs.268573 [ NCBI ]
CGAP (NCI)Hs.268573
Gene ExpressionGSTT1 [ NCBI-GEO ]   GSTT1 [ EBI - ARRAY_EXPRESS ]   GSTT1 [ SEEK ]   GSTT1 [ MEM ]
Gene Expression Viewer (FireBrowse)GSTT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2952
GTEX Portal (Tissue expression)GSTT1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP30711   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP30711  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP30711
Splice isoforms : SwissVarP30711
Catalytic activity : Enzyme2.5.1.18 [ Enzyme-Expasy ]   2.5.1.182.5.1.18 [ IntEnz-EBI ]   2.5.1.18 [ BRENDA ]   2.5.1.18 [ KEGG ]   
PhosPhoSitePlusP30711
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    GST_C    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)GST_C (PF00043)    GST_N (PF02798)   
Domain families : Pfam (NCBI)pfam00043    pfam02798   
Conserved Domain (NCBI)GSTT1
DMDM Disease mutations2952
Blocks (Seattle)GSTT1
PDB (SRS)2C3N    2C3Q    2C3T   
PDB (PDBSum)2C3N    2C3Q    2C3T   
PDB (IMB)2C3N    2C3Q    2C3T   
PDB (RSDB)2C3N    2C3Q    2C3T   
Structural Biology KnowledgeBase2C3N    2C3Q    2C3T   
SCOP (Structural Classification of Proteins)2C3N    2C3Q    2C3T   
CATH (Classification of proteins structures)2C3N    2C3Q    2C3T   
SuperfamilyP30711
Peptide AtlasP30711
HPRD02700
IPIIPI00741097   IPI00924629   IPI00607741   IPI00940999   IPI00877869   IPI00877649   IPI00877842   IPI00877945   IPI00878151   IPI00893432   IPI00893316   
Protein Interaction databases
DIP (DOE-UCLA)P30711
IntAct (EBI)P30711
BioGRIDGSTT1
STRING (EMBL)GSTT1
ZODIACGSTT1
Ontologies - Pathways
QuickGOP30711
Ontology : AmiGOglutathione transferase activity  glutathione transferase activity  glutathione peroxidase activity  cytosol  cytosol  glutathione metabolic process  extracellular exosome  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Ontology : EGO-EBIglutathione transferase activity  glutathione transferase activity  glutathione peroxidase activity  cytosol  cytosol  glutathione metabolic process  extracellular exosome  cellular oxidant detoxification  glutathione derivative biosynthetic process  
Pathways : KEGGGlutathione metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx NetworkGSTT1
Atlas of Cancer Signalling NetworkGSTT1
Wikipedia pathwaysGSTT1
Orthology - Evolution
OrthoDB2952
Phylogenetic Trees/Animal Genes : TreeFamGSTT1
HOVERGENP30711
HOGENOMP30711
Homologs : HomoloGeneGSTT1
Homology/Alignments : Family Browser (UCSC)GSTT1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerGSTT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)GSTT1
dbVarGSTT1
ClinVarGSTT1
1000_GenomesGSTT1 
Exome Variant ServerGSTT1
ExAC (Exome Aggregation Consortium)GSTT1 (select the gene name)
Genetic variants : HAPMAP2952
Genomic Variants (DGV)GSTT1 [DGVbeta]
DECIPHER (Syndromes)22:24376133-24384311  
CONAN: Copy Number AnalysisGSTT1 
Mutations
ICGC Data PortalGSTT1 
TCGA Data PortalGSTT1 
Broad Tumor PortalGSTT1
OASIS PortalGSTT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICGSTT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDGSTT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Pharmacogenomics of Infectious Diseases (PGx_IfD )
BioMutasearch GSTT1
DgiDB (Drug Gene Interaction Database)GSTT1
DoCM (Curated mutations)GSTT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)GSTT1 (select a term)
intoGenGSTT1
Cancer3DGSTT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600436   
Orphanet
MedgenGSTT1
Genetic Testing Registry GSTT1
NextProtP30711 [Medical]
TSGene2952
GENETestsGSTT1
Huge Navigator GSTT1 [HugePedia]
snp3D : Map Gene to Disease2952
BioCentury BCIQGSTT1
ClinGenGSTT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2952
Chemical/Pharm GKB GenePA183
Clinical trialGSTT1
Miscellaneous
canSAR (ICR)GSTT1 (select the gene name)
Probes
Litterature
PubMed499 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineGSTT1
EVEXGSTT1
GoPubMedGSTT1
iHOPGSTT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:03:11 CEST 2017

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