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HAT1 (histone acetyltransferase 1)

Identity

Alias_symbol (synonym)KAT1
Other alias
HGNC (Hugo) HAT1
LocusID (NCBI) 8520
Atlas_Id 40788
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 171922425 and ends at 171983686 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HAT1 (2q31.1) / EXOC6B (2p13.2)HAT1 (2q31.1) / TRMT11 (6q22.32)LOC400043 (12q13.13) / HAT1 (2q31.1)
HAT1 2q31.1 / EXOC6B 2p13.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HAT1   4821
Cards
Entrez_Gene (NCBI)HAT1  8520  histone acetyltransferase 1
AliasesKAT1
GeneCards (Weizmann)HAT1
Ensembl hg19 (Hinxton)ENSG00000128708 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000128708 [Gene_View]  chr2:171922425-171983686 [Contig_View]  HAT1 [Vega]
ICGC DataPortalENSG00000128708
TCGA cBioPortalHAT1
AceView (NCBI)HAT1
Genatlas (Paris)HAT1
WikiGenes8520
SOURCE (Princeton)HAT1
Genetics Home Reference (NIH)HAT1
Genomic and cartography
GoldenPath hg38 (UCSC)HAT1  -     chr2:171922425-171983686 +  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HAT1  -     2q31.1   [Description]    (hg19-Feb_2009)
EnsemblHAT1 - 2q31.1 [CytoView hg19]  HAT1 - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIHAT1 [Mapview hg19]  HAT1 [Mapview hg38]
OMIM603053   
Gene and transcription
Genbank (Entrez)AF030424 AK127840 AK309001 AK313699 BC018682
RefSeq transcript (Entrez)NM_001033085 NM_003642
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HAT1
Cluster EST : UnigeneHs.632532 [ NCBI ]
CGAP (NCI)Hs.632532
Alternative Splicing GalleryENSG00000128708
Gene ExpressionHAT1 [ NCBI-GEO ]   HAT1 [ EBI - ARRAY_EXPRESS ]   HAT1 [ SEEK ]   HAT1 [ MEM ]
Gene Expression Viewer (FireBrowse)HAT1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8520
GTEX Portal (Tissue expression)HAT1
Human Protein AtlasENSG00000128708-HAT1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO14929   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO14929  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO14929
Splice isoforms : SwissVarO14929
PhosPhoSitePlusO14929
Domains : Interpro (EBI)Acyl_CoA_acyltransferase    Hat1_N    Hist_AcTrfase_B-typ_cat-su   
Domain families : Pfam (Sanger)Hat1_N (PF10394)   
Domain families : Pfam (NCBI)pfam10394   
Conserved Domain (NCBI)HAT1
DMDM Disease mutations8520
Blocks (Seattle)HAT1
PDB (SRS)2P0W   
PDB (PDBSum)2P0W   
PDB (IMB)2P0W   
PDB (RSDB)2P0W   
Structural Biology KnowledgeBase2P0W   
SCOP (Structural Classification of Proteins)2P0W   
CATH (Classification of proteins structures)2P0W   
SuperfamilyO14929
Human Protein Atlas [tissue]ENSG00000128708-HAT1 [tissue]
Peptide AtlasO14929
HPRD04339
IPIIPI00024719   IPI00651621   IPI00916759   IPI00916606   
Protein Interaction databases
DIP (DOE-UCLA)O14929
IntAct (EBI)O14929
FunCoupENSG00000128708
BioGRIDHAT1
STRING (EMBL)HAT1
ZODIACHAT1
Ontologies - Pathways
QuickGOO14929
Ontology : AmiGOnuclear chromosome, telomeric region  nuclear chromatin  histone acetyltransferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  DNA packaging  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  chromatin silencing at telomere  internal protein amino acid acetylation  response to nutrient  H4 histone acetyltransferase activity  nuclear matrix  histone binding  intracellular membrane-bounded organelle  protein complex  histone H4 acetylation  
Ontology : EGO-EBInuclear chromosome, telomeric region  nuclear chromatin  histone acetyltransferase activity  protein binding  nucleus  nucleoplasm  nucleoplasm  cytoplasm  DNA packaging  DNA replication-dependent nucleosome assembly  DNA replication-independent nucleosome assembly  chromatin silencing at telomere  internal protein amino acid acetylation  response to nutrient  H4 histone acetyltransferase activity  nuclear matrix  histone binding  intracellular membrane-bounded organelle  protein complex  histone H4 acetylation  
Pathways : KEGGAlcoholism   
NDEx NetworkHAT1
Atlas of Cancer Signalling NetworkHAT1
Wikipedia pathwaysHAT1
Orthology - Evolution
OrthoDB8520
GeneTree (enSembl)ENSG00000128708
Phylogenetic Trees/Animal Genes : TreeFamHAT1
HOVERGENO14929
HOGENOMO14929
Homologs : HomoloGeneHAT1
Homology/Alignments : Family Browser (UCSC)HAT1
Gene fusions - Rearrangements
Fusion : MitelmanHAT1/EXOC6B [2q31.1/2p13.2]  
Fusion: TCGA_MDACCHAT1 2q31.1 EXOC6B 2p13.2 LUAD
Tumor Fusion PortalHAT1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHAT1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HAT1
dbVarHAT1
ClinVarHAT1
1000_GenomesHAT1 
Exome Variant ServerHAT1
ExAC (Exome Aggregation Consortium)ENSG00000128708
GNOMAD BrowserENSG00000128708
Genetic variants : HAPMAP8520
Genomic Variants (DGV)HAT1 [DGVbeta]
DECIPHERHAT1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHAT1 
Mutations
ICGC Data PortalHAT1 
TCGA Data PortalHAT1 
Broad Tumor PortalHAT1
OASIS PortalHAT1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHAT1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHAT1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HAT1
DgiDB (Drug Gene Interaction Database)HAT1
DoCM (Curated mutations)HAT1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HAT1 (select a term)
intoGenHAT1
Cancer3DHAT1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603053   
Orphanet
DisGeNETHAT1
MedgenHAT1
Genetic Testing Registry HAT1
NextProtO14929 [Medical]
TSGene8520
GENETestsHAT1
Target ValidationHAT1
Huge Navigator HAT1 [HugePedia]
snp3D : Map Gene to Disease8520
BioCentury BCIQHAT1
ClinGenHAT1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8520
Chemical/Pharm GKB GenePA29197
Clinical trialHAT1
Miscellaneous
canSAR (ICR)HAT1 (select the gene name)
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHAT1
EVEXHAT1
GoPubMedHAT1
iHOPHAT1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:15:45 CET 2017

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