HCK (hemopoietic cell kinase)

Identity

Other names	JTK9
HGNC	HCK
Location	20q11-q12
Location_base_pair	Starts at 30103718 and ends at 30153318 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	HCK   4840
Entrez_Gene	HCK  3055  hemopoietic cell kinase
	Cards
GeneCards	HCK
Ensembl	HCK [Search_View]   ENSG00000101336 [Gene_View]
Genatlas	HCK
GeneLynx	HCK
eGenome	HCK
euGene	3055
	Genomic and cartography
GoldenPath	HCK  -     chr20:30103718-30153318 +  20q11.21   [Description]    (hg18-March_2006)
Ensembl	HCK - 20q11.21 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	HCK
	Gene and transcription
Genbank	AK026432 [ ENTREZ ]
Genbank	AK225819 [ ENTREZ ]
Genbank	AK289896 [ ENTREZ ]
Genbank	AK290928 [ ENTREZ ]
Genbank	AK298726 [ ENTREZ ]
RefSeq	NM_002110 [ SRS ]    NM_002110 [ ENTREZ ]
RefSeq	AC_000063 [ SRS ]    AC_000063 [ ENTREZ ]
RefSeq	AC_000152 [ SRS ]    AC_000152 [ ENTREZ ]
RefSeq	NC_000020 [ SRS ]    NC_000020 [ ENTREZ ]
RefSeq	NT_028392 [ SRS ]    NT_028392 [ ENTREZ ]
RefSeq	NW_001838664 [ SRS ]    NW_001838664 [ ENTREZ ]
RefSeq	NW_927339 [ SRS ]    NW_927339 [ ENTREZ ]
AceView	HCK AceView - NCBI
Unigene	Hs.655210 [ SRS ]    Hs.655210 [ NCBI ]     HS655210 [ spliceNest ]
Fast-db	7746 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P08631 [ SRS]    P08631 [ EXPASY ]     P08631 [ INTERPRO ]     P08631 [ UNIPROT ]
Prosite	PS00107 PROTEIN_KINASE_ATP [ SRS ]    PS00107 PROTEIN_KINASE_ATP [ Expasy ]
Prosite	PS50011 PROTEIN_KINASE_DOM [ SRS ]    PS50011 PROTEIN_KINASE_DOM [ Expasy ]
Prosite	PS00109 PROTEIN_KINASE_TYR [ SRS ]    PS00109 PROTEIN_KINASE_TYR [ Expasy ]
Prosite	PS50001 SH2 [ SRS ]    PS50001 SH2 [ Expasy ]
Prosite	PS50002 SH3 [ SRS ]    PS50002 SH3 [ Expasy ]
Interpro	IPR000719 Prot_kinase_core [ SRS ]    IPR000719 Prot_kinase_core [ EBI ]
Interpro	IPR017441 Protein_kinase_ATP_bd_CS [ SRS ]    IPR017441 Protein_kinase_ATP_bd_CS [ EBI ]
Interpro	IPR000980 SH2 [ SRS ]    IPR000980 SH2 [ EBI ]
Interpro	IPR001452 SH3 [ SRS ]    IPR001452 SH3 [ EBI ]
Interpro	IPR001245 Tyr_pkinase [ SRS ]    IPR001245 Tyr_pkinase [ EBI ]
Interpro	IPR008266 Tyr_pkinase_AS [ SRS ]    IPR008266 Tyr_pkinase_AS [ EBI ]
CluSTr	P08631
Pfam	PF07714 Pkinase_Tyr [ SRS ]    PF07714 Pkinase_Tyr [ Sanger ]    pfam07714 [ NCBI-CDD ]
Pfam	PF00017 SH2 [ SRS ]    PF00017 SH2 [ Sanger ]    pfam00017 [ NCBI-CDD ]
Pfam	PF00018 SH3_1 [ SRS ]    PF00018 SH3_1 [ Sanger ]    pfam00018 [ NCBI-CDD ]
Smart	SM00252 SH2 [EMBL]
Smart	SM00326 SH3 [EMBL]
Smart	SM00219 TyrKc [EMBL]
Prodom	PD000001 Prot_kinase[INRA-Toulouse]
Prodom	P08631 HCK_HUMAN [ Domain structure ]   P08631 HCK_HUMAN  [ sequences sharing at least 1 domain ]
Prodom	PD000001[INRA-Toulouse]
Prodom	P08631 HCK_HUMAN [ Domain structure ]   P08631 HCK_HUMAN  [ sequences sharing at least 1 domain ]
Prodom	PD000001[INRA-Toulouse]
Prodom	P08631 HCK_HUMAN [ Domain structure ]   P08631 HCK_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P08631
PDB	1AD5 [ SRS ]    1AD5 [ PdbSum ],   1AD5 [ IMB ]   1AD5 [ RSDB ]
PDB	1BU1 [ SRS ]    1BU1 [ PdbSum ],   1BU1 [ IMB ]   1BU1 [ RSDB ]
PDB	1QCF [ SRS ]    1QCF [ PdbSum ],   1QCF [ IMB ]   1QCF [ RSDB ]
PDB	2C0I [ SRS ]    2C0I [ PdbSum ],   2C0I [ IMB ]   2C0I [ RSDB ]
PDB	2C0O [ SRS ]    2C0O [ PdbSum ],   2C0O [ IMB ]   2C0O [ RSDB ]
PDB	2C0T [ SRS ]    2C0T [ PdbSum ],   2C0T [ IMB ]   2C0T [ RSDB ]
PDB	2HCK [ SRS ]    2HCK [ PdbSum ],   2HCK [ IMB ]   2HCK [ RSDB ]
PDB	2HK5 [ SRS ]    2HK5 [ PdbSum ],   2HK5 [ IMB ]   2HK5 [ RSDB ]
PDB	2OI3 [ SRS ]    2OI3 [ PdbSum ],   2OI3 [ IMB ]   2OI3 [ RSDB ]
PDB	2OJ2 [ SRS ]    2OJ2 [ PdbSum ],   2OJ2 [ IMB ]   2OJ2 [ RSDB ]
PDB	3HCK [ SRS ]    3HCK [ PdbSum ],   3HCK [ IMB ]   3HCK [ RSDB ]
PDB	4HCK [ SRS ]    4HCK [ PdbSum ],   4HCK [ IMB ]   4HCK [ RSDB ]
PDB	5HCK [ SRS ]    5HCK [ PdbSum ],   5HCK [ IMB ]   5HCK [ RSDB ]
HPRD	00796
	Protein Interaction databases
DIP	P08631
IntAct	P08631
	Polymorphism : SNP, mutations, diseases
OMIM	142370    [ map ]
GENECLINICS	142370
SNP	HCK [dbSNP-NCBI]
SNP	NM_002110 [SNP-NCI]
SNP	HCK [GeneSNPs - Utah]  HCK] [HGBASE - SRS]
HAPMAP	HCK [HAPMAP]
COSMIC	HCK [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	HCK
	General knowledge
Family Browser	HCK [UCSC Family Browser]
SOURCE	NM_002110
SMD	Hs.655210
SAGE	Hs.655210
Enzyme	2.7.10.2 [ Enzyme-Expasy ]   2.7.10.2 [ Enzyme-SRS ]   2.7.10.2 [ IntEnz-EBI ]   2.7.10.2 [ BRENDA ]   2.7.10.2 [ KEGG ]   2.7.10.2 [ WIT ]
GO	nucleotide binding [Amigo]  nucleotide binding
GO	non-membrane spanning protein tyrosine kinase activity [Amigo]  non-membrane spanning protein tyrosine kinase activity
GO	protein binding [Amigo]  protein binding
GO	ATP binding [Amigo]  ATP binding
GO	cytoplasm [Amigo]  cytoplasm
GO	protein amino acid phosphorylation [Amigo]  protein amino acid phosphorylation
GO	mesoderm development [Amigo]  mesoderm development
GO	membrane [Amigo]  membrane
GO	transferase activity [Amigo]  transferase activity
GO	interspecies interaction between organisms [Amigo]  interspecies interaction between organisms
BIOCARTA	Roles of §-arrestin-dependent Recruitment of Src Kinases in GPCR Signaling    [Genes]
BIOCARTA	HIV-1 defeats host-mediated resistance by CEM15    [Genes]
PubGene	HCK
TreeFam	HCK
CTD	3055 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	HCK Related clones (RZPD - Berlin)
	PubMed
PubMed	123 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:44:21 2008