Atlas of Genetics and Cytogenetics in Oncology and Haematology


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HCK (HCK proto-oncogene, Src family tyrosine kinase)

Identity

Alias (NCBI)JTK9
p59Hck
p61Hck
HGNC (Hugo) HCK
HGNC Alias symbJTK9
HGNC Previous namehemopoietic cell kinase
LocusID (NCBI) 3055
Atlas_Id 40798
Location 20q11.21  [Link to chromosome band 20q11]
Location_base_pair Starts at 32052242 and ends at 32101842 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
HCK (20q11.21) / CCM2L (20q11.21)HCK (20q11.21) / ENG (9q34.11)HCK (20q11.21) / NOL4L20q11.21 ()
RPL37A (2q35) / HCK (20q11.21)HCK 20q11.21 C20orf160

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 2 ]
  del(11)(q23q23) KMT2A/CBL::t(11;11)(q23;q23) KMT2A/CBL
t(20;20)(q11;q11) POFUT1/HCK


External links

Nomenclature
HGNC (Hugo)HCK   4840
Cards
Entrez_Gene (NCBI)HCK    HCK proto-oncogene, Src family tyrosine kinase
AliasesJTK9; p59Hck; p61Hck
GeneCards (Weizmann)HCK
Ensembl hg19 (Hinxton)ENSG00000101336 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101336 [Gene_View]  ENSG00000101336 [Sequence]  chr20:32052242-32101842 [Contig_View]  HCK [Vega]
ICGC DataPortalENSG00000101336
TCGA cBioPortalHCK
AceView (NCBI)HCK
Genatlas (Paris)HCK
SOURCE (Princeton)HCK
Genetics Home Reference (NIH)HCK
Genomic and cartography
GoldenPath hg38 (UCSC)HCK  -     chr20:32052242-32101842 +  20q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HCK  -     20q11.21   [Description]    (hg19-Feb_2009)
GoldenPathHCK - 20q11.21 [CytoView hg19]  HCK - 20q11.21 [CytoView hg38]
ImmunoBaseENSG00000101336
genome Data Viewer NCBIHCK [Mapview hg19]  
OMIM142370   
Gene and transcription
Genbank (Entrez)AK026432 AK225819 AK289896 AK290928 AK298726
RefSeq transcript (Entrez)NM_001172129 NM_001172130 NM_001172131 NM_001172132 NM_001172133 NM_002110
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HCK
Alternative Splicing GalleryENSG00000101336
Gene ExpressionHCK [ NCBI-GEO ]   HCK [ EBI - ARRAY_EXPRESS ]   HCK [ SEEK ]   HCK [ MEM ]
Gene Expression Viewer (FireBrowse)HCK [ Firebrowse - Broad ]
GenevisibleExpression of HCK in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3055
GTEX Portal (Tissue expression)HCK
Human Protein AtlasENSG00000101336-HCK [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)HCK
Blocks (Seattle)HCK
Human Protein Atlas [tissue]ENSG00000101336-HCK [tissue]
HPRD00796
IPIIPI00646510   IPI00029769   IPI00430857   IPI00956008   IPI00956028   IPI00946888   IPI00946157   IPI00946853   
Protein Interaction databases
BioGRIDHCK
STRING (EMBL)HCK
ZODIACHCK
Ontologies - Pathways
Litterature
PubMed240 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXHCK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:24:40 CET 2021

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