Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HRH2 (histamine receptor H2)

Identity

Other aliasH2R
HGNC (Hugo) HRH2
LocusID (NCBI) 3274
Atlas_Id 43658
Location 5q35.2  [Link to chromosome band 5q35]
Location_base_pair Starts at 175658037 and ends at 175686242 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HRH2   5183
Cards
Entrez_Gene (NCBI)HRH2  3274  histamine receptor H2
AliasesH2R
GeneCards (Weizmann)HRH2
Ensembl hg19 (Hinxton)ENSG00000113749 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000113749 [Gene_View]  chr5:175658037-175686242 [Contig_View]  HRH2 [Vega]
ICGC DataPortalENSG00000113749
TCGA cBioPortalHRH2
AceView (NCBI)HRH2
Genatlas (Paris)HRH2
WikiGenes3274
SOURCE (Princeton)HRH2
Genetics Home Reference (NIH)HRH2
Genomic and cartography
GoldenPath hg38 (UCSC)HRH2  -     chr5:175658037-175686242 +  5q35.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HRH2  -     5q35.2   [Description]    (hg19-Feb_2009)
EnsemblHRH2 - 5q35.2 [CytoView hg19]  HRH2 - 5q35.2 [CytoView hg38]
Mapping of homologs : NCBIHRH2 [Mapview hg19]  HRH2 [Mapview hg38]
OMIM142703   
Gene and transcription
Genbank (Entrez)AB023487 AB451483 AY136744 BC054510 CF147823
RefSeq transcript (Entrez)NM_001131055 NM_022304
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HRH2
Cluster EST : UnigeneHs.247885 [ NCBI ]
CGAP (NCI)Hs.247885
Alternative Splicing GalleryENSG00000113749
Gene ExpressionHRH2 [ NCBI-GEO ]   HRH2 [ EBI - ARRAY_EXPRESS ]   HRH2 [ SEEK ]   HRH2 [ MEM ]
Gene Expression Viewer (FireBrowse)HRH2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3274
GTEX Portal (Tissue expression)HRH2
Human Protein AtlasENSG00000113749-HRH2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP25021   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP25021  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP25021
Splice isoforms : SwissVarP25021
PhosPhoSitePlusP25021
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Histamine_H2_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Domain families : Smart (EMBL)7TM_GPCR_Srsx (SM01381)  
Conserved Domain (NCBI)HRH2
DMDM Disease mutations3274
Blocks (Seattle)HRH2
SuperfamilyP25021
Human Protein Atlas [tissue]ENSG00000113749-HRH2 [tissue]
Peptide AtlasP25021
HPRD00816
IPIIPI00744547   IPI00012312   
Protein Interaction databases
DIP (DOE-UCLA)P25021
IntAct (EBI)P25021
FunCoupENSG00000113749
BioGRIDHRH2
STRING (EMBL)HRH2
ZODIACHRH2
Ontologies - Pathways
QuickGOP25021
Ontology : AmiGOhistamine-induced gastric acid secretion  gastrin-induced gastric acid secretion  epithelial cell morphogenesis  histamine receptor activity  plasma membrane  integral component of plasma membrane  immune response  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  memory  visual learning  positive regulation of vasoconstriction  regulation of synaptic plasticity  digestive tract development  gland development  toxin transport  
Ontology : EGO-EBIhistamine-induced gastric acid secretion  gastrin-induced gastric acid secretion  epithelial cell morphogenesis  histamine receptor activity  plasma membrane  integral component of plasma membrane  immune response  G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger  memory  visual learning  positive regulation of vasoconstriction  regulation of synaptic plasticity  digestive tract development  gland development  toxin transport  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction    Gastric acid secretion   
NDEx NetworkHRH2
Atlas of Cancer Signalling NetworkHRH2
Wikipedia pathwaysHRH2
Orthology - Evolution
OrthoDB3274
GeneTree (enSembl)ENSG00000113749
Phylogenetic Trees/Animal Genes : TreeFamHRH2
HOVERGENP25021
HOGENOMP25021
Homologs : HomoloGeneHRH2
Homology/Alignments : Family Browser (UCSC)HRH2
Gene fusions - Rearrangements
Tumor Fusion PortalHRH2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHRH2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HRH2
dbVarHRH2
ClinVarHRH2
1000_GenomesHRH2 
Exome Variant ServerHRH2
ExAC (Exome Aggregation Consortium)ENSG00000113749
GNOMAD BrowserENSG00000113749
Genetic variants : HAPMAP3274
Genomic Variants (DGV)HRH2 [DGVbeta]
DECIPHERHRH2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHRH2 
Mutations
ICGC Data PortalHRH2 
TCGA Data PortalHRH2 
Broad Tumor PortalHRH2
OASIS PortalHRH2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHRH2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHRH2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HRH2
DgiDB (Drug Gene Interaction Database)HRH2
DoCM (Curated mutations)HRH2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HRH2 (select a term)
intoGenHRH2
Cancer3DHRH2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM142703   
Orphanet
DisGeNETHRH2
MedgenHRH2
Genetic Testing Registry HRH2
NextProtP25021 [Medical]
TSGene3274
GENETestsHRH2
Target ValidationHRH2
Huge Navigator HRH2 [HugePedia]
snp3D : Map Gene to Disease3274
BioCentury BCIQHRH2
ClinGenHRH2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3274
Chemical/Pharm GKB GenePA29457
Clinical trialHRH2
Miscellaneous
canSAR (ICR)HRH2 (select the gene name)
Probes
Litterature
PubMed67 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHRH2
EVEXHRH2
GoPubMedHRH2
iHOPHRH2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:16:51 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.