Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

HSPA2 (heat shock protein family A (Hsp70) member 2)

Identity

Alias_namesheat shock 70kD protein 2
heat shock 70kDa protein 2
Other aliasHSP70-2
HSP70-3
HGNC (Hugo) HSPA2
LocusID (NCBI) 3306
Atlas_Id 40874
Location 14q23.3  [Link to chromosome band 14q23]
Location_base_pair Starts at 64540468 and ends at 64543236 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EIF4A1 (17p13.1) / HSPA2 (14q23.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)HSPA2   5235
Cards
Entrez_Gene (NCBI)HSPA2  3306  heat shock protein family A (Hsp70) member 2
AliasesHSP70-2; HSP70-3
GeneCards (Weizmann)HSPA2
Ensembl hg19 (Hinxton)ENSG00000126803 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126803 [Gene_View]  chr14:64540468-64543236 [Contig_View]  HSPA2 [Vega]
ICGC DataPortalENSG00000126803
TCGA cBioPortalHSPA2
AceView (NCBI)HSPA2
Genatlas (Paris)HSPA2
WikiGenes3306
SOURCE (Princeton)HSPA2
Genetics Home Reference (NIH)HSPA2
Genomic and cartography
GoldenPath hg38 (UCSC)HSPA2  -     chr14:64540468-64543236 +  14q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)HSPA2  -     14q23.3   [Description]    (hg19-Feb_2009)
EnsemblHSPA2 - 14q23.3 [CytoView hg19]  HSPA2 - 14q23.3 [CytoView hg38]
Mapping of homologs : NCBIHSPA2 [Mapview hg19]  HSPA2 [Mapview hg38]
OMIM140560   
Gene and transcription
Genbank (Entrez)AK097824 BC001752 BC034365 BC036107 BG772858
RefSeq transcript (Entrez)NM_021979
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)HSPA2
Cluster EST : UnigeneHs.432648 [ NCBI ]
CGAP (NCI)Hs.432648
Alternative Splicing GalleryENSG00000126803
Gene ExpressionHSPA2 [ NCBI-GEO ]   HSPA2 [ EBI - ARRAY_EXPRESS ]   HSPA2 [ SEEK ]   HSPA2 [ MEM ]
Gene Expression Viewer (FireBrowse)HSPA2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)3306
GTEX Portal (Tissue expression)HSPA2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP54652   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP54652  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP54652
Splice isoforms : SwissVarP54652
PhosPhoSitePlusP54652
Domaine pattern : Prosite (Expaxy)HSP70_1 (PS00297)    HSP70_2 (PS00329)    HSP70_3 (PS01036)   
Domains : Interpro (EBI)Heat_shock_70_CS    HSP70_C    HSP70_peptide-bd    Hsp_70_fam   
Domain families : Pfam (Sanger)HSP70 (PF00012)   
Domain families : Pfam (NCBI)pfam00012   
Conserved Domain (NCBI)HSPA2
DMDM Disease mutations3306
Blocks (Seattle)HSPA2
PDB (SRS)3I33    4FSV    5FPD    5FPE    5FPM    5FPN   
PDB (PDBSum)3I33    4FSV    5FPD    5FPE    5FPM    5FPN   
PDB (IMB)3I33    4FSV    5FPD    5FPE    5FPM    5FPN   
PDB (RSDB)3I33    4FSV    5FPD    5FPE    5FPM    5FPN   
Structural Biology KnowledgeBase3I33    4FSV    5FPD    5FPE    5FPM    5FPN   
SCOP (Structural Classification of Proteins)3I33    4FSV    5FPD    5FPE    5FPM    5FPN   
CATH (Classification of proteins structures)3I33    4FSV    5FPD    5FPE    5FPM    5FPN   
SuperfamilyP54652
Human Protein AtlasENSG00000126803
Peptide AtlasP54652
HPRD07174
IPIIPI00007702   IPI00902596   
Protein Interaction databases
DIP (DOE-UCLA)P54652
IntAct (EBI)P54652
FunCoupENSG00000126803
BioGRIDHSPA2
STRING (EMBL)HSPA2
ZODIACHSPA2
Ontologies - Pathways
QuickGOP54652
Ontology : AmiGOprotein binding  ATP binding  nucleus  cytosol  response to unfolded protein  male meiotic nuclear division  spermatogenesis  spermatid development  response to heat  response to cold  membrane  enzyme binding  CatSper complex  protein refolding  unfolded protein binding  extracellular exosome  blood microparticle  meiotic spindle  negative regulation of inclusion body assembly  disordered domain specific binding  
Ontology : EGO-EBIprotein binding  ATP binding  nucleus  cytosol  response to unfolded protein  male meiotic nuclear division  spermatogenesis  spermatid development  response to heat  response to cold  membrane  enzyme binding  CatSper complex  protein refolding  unfolded protein binding  extracellular exosome  blood microparticle  meiotic spindle  negative regulation of inclusion body assembly  disordered domain specific binding  
Pathways : KEGG   
NDEx NetworkHSPA2
Atlas of Cancer Signalling NetworkHSPA2
Wikipedia pathwaysHSPA2
Orthology - Evolution
OrthoDB3306
GeneTree (enSembl)ENSG00000126803
Phylogenetic Trees/Animal Genes : TreeFamHSPA2
HOVERGENP54652
HOGENOMP54652
Homologs : HomoloGeneHSPA2
Homology/Alignments : Family Browser (UCSC)HSPA2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerHSPA2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)HSPA2
dbVarHSPA2
ClinVarHSPA2
1000_GenomesHSPA2 
Exome Variant ServerHSPA2
ExAC (Exome Aggregation Consortium)HSPA2 (select the gene name)
Genetic variants : HAPMAP3306
Genomic Variants (DGV)HSPA2 [DGVbeta]
DECIPHERHSPA2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisHSPA2 
Mutations
ICGC Data PortalHSPA2 
TCGA Data PortalHSPA2 
Broad Tumor PortalHSPA2
OASIS PortalHSPA2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICHSPA2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDHSPA2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch HSPA2
DgiDB (Drug Gene Interaction Database)HSPA2
DoCM (Curated mutations)HSPA2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)HSPA2 (select a term)
intoGenHSPA2
Cancer3DHSPA2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM140560   
Orphanet
MedgenHSPA2
Genetic Testing Registry HSPA2
NextProtP54652 [Medical]
TSGene3306
GENETestsHSPA2
Huge Navigator HSPA2 [HugePedia]
snp3D : Map Gene to Disease3306
BioCentury BCIQHSPA2
ClinGenHSPA2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD3306
Chemical/Pharm GKB GenePA29501
Clinical trialHSPA2
Miscellaneous
canSAR (ICR)HSPA2 (select the gene name)
Probes
Litterature
PubMed114 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineHSPA2
EVEXHSPA2
GoPubMedHSPA2
iHOPHSPA2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:19:39 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.