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IER5 (immediate early response 5)

Identity

Other aliasSBBI48
HGNC (Hugo) IER5
LocusID (NCBI) 51278
Atlas_Id 46759
Location 1q25.3  [Link to chromosome band 1q25]
Location_base_pair Starts at 181088502 and ends at 181090843 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)IER5   5393
Cards
Entrez_Gene (NCBI)IER5  51278  immediate early response 5
AliasesSBBI48
GeneCards (Weizmann)IER5
Ensembl hg19 (Hinxton)ENSG00000162783 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162783 [Gene_View]  chr1:181088502-181090843 [Contig_View]  IER5 [Vega]
ICGC DataPortalENSG00000162783
TCGA cBioPortalIER5
AceView (NCBI)IER5
Genatlas (Paris)IER5
WikiGenes51278
SOURCE (Princeton)IER5
Genetics Home Reference (NIH)IER5
Genomic and cartography
GoldenPath hg38 (UCSC)IER5  -     chr1:181088502-181090843 +  1q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IER5  -     1q25.3   [Description]    (hg19-Feb_2009)
EnsemblIER5 - 1q25.3 [CytoView hg19]  IER5 - 1q25.3 [CytoView hg38]
Mapping of homologs : NCBIIER5 [Mapview hg19]  IER5 [Mapview hg38]
OMIM607177   
Gene and transcription
Genbank (Entrez)AA235294 AF178984 AF258581 AI696140 AJ251089
RefSeq transcript (Entrez)NM_016545
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IER5
Cluster EST : UnigeneHs.15725 [ NCBI ]
CGAP (NCI)Hs.15725
Alternative Splicing GalleryENSG00000162783
Gene ExpressionIER5 [ NCBI-GEO ]   IER5 [ EBI - ARRAY_EXPRESS ]   IER5 [ SEEK ]   IER5 [ MEM ]
Gene Expression Viewer (FireBrowse)IER5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51278
GTEX Portal (Tissue expression)IER5
Human Protein AtlasENSG00000162783-IER5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5VY09   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5VY09  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5VY09
Splice isoforms : SwissVarQ5VY09
PhosPhoSitePlusQ5VY09
Domains : Interpro (EBI)IER   
Domain families : Pfam (Sanger)IER (PF05760)   
Domain families : Pfam (NCBI)pfam05760   
Conserved Domain (NCBI)IER5
DMDM Disease mutations51278
Blocks (Seattle)IER5
SuperfamilyQ5VY09
Human Protein Atlas [tissue]ENSG00000162783-IER5 [tissue]
Peptide AtlasQ5VY09
HPRD06210
IPIIPI00292208   IPI00973209   
Protein Interaction databases
DIP (DOE-UCLA)Q5VY09
IntAct (EBI)Q5VY09
FunCoupENSG00000162783
BioGRIDIER5
STRING (EMBL)IER5
ZODIACIER5
Ontologies - Pathways
QuickGOQ5VY09
Ontology : AmiGOprotein phosphatase type 2A complex  protein binding  nucleus  cytoplasm  transcription, DNA-templated  cellular response to heat  regulation of cell proliferation  identical protein binding  identical protein binding  positive regulation of transcription by RNA polymerase II  positive regulation of cellular response to heat  
Ontology : EGO-EBIprotein phosphatase type 2A complex  protein binding  nucleus  cytoplasm  transcription, DNA-templated  cellular response to heat  regulation of cell proliferation  identical protein binding  identical protein binding  positive regulation of transcription by RNA polymerase II  positive regulation of cellular response to heat  
NDEx NetworkIER5
Atlas of Cancer Signalling NetworkIER5
Wikipedia pathwaysIER5
Orthology - Evolution
OrthoDB51278
GeneTree (enSembl)ENSG00000162783
Phylogenetic Trees/Animal Genes : TreeFamIER5
HOVERGENQ5VY09
HOGENOMQ5VY09
Homologs : HomoloGeneIER5
Homology/Alignments : Family Browser (UCSC)IER5
Gene fusions - Rearrangements
Fusion : QuiverIER5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIER5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IER5
dbVarIER5
ClinVarIER5
1000_GenomesIER5 
Exome Variant ServerIER5
ExAC (Exome Aggregation Consortium)ENSG00000162783
GNOMAD BrowserENSG00000162783
Genetic variants : HAPMAP51278
Genomic Variants (DGV)IER5 [DGVbeta]
DECIPHERIER5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIER5 
Mutations
ICGC Data PortalIER5 
TCGA Data PortalIER5 
Broad Tumor PortalIER5
OASIS PortalIER5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIER5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIER5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IER5
DgiDB (Drug Gene Interaction Database)IER5
DoCM (Curated mutations)IER5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IER5 (select a term)
intoGenIER5
Cancer3DIER5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607177   
Orphanet
DisGeNETIER5
MedgenIER5
Genetic Testing Registry IER5
NextProtQ5VY09 [Medical]
TSGene51278
GENETestsIER5
Target ValidationIER5
Huge Navigator IER5 [HugePedia]
snp3D : Map Gene to Disease51278
BioCentury BCIQIER5
ClinGenIER5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51278
Chemical/Pharm GKB GenePA29640
Clinical trialIER5
Miscellaneous
canSAR (ICR)IER5 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIER5
EVEXIER5
GoPubMedIER5
iHOPIER5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon May 14 11:52:00 CEST 2018
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