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IFI6 (interferon alpha inducible protein 6)

Identity

Alias_namesG1P3
interferon
Alias_symbol (synonym)IFI616
FAM14C
6-16
IFI-6-16
Other alias
HGNC (Hugo) IFI6
LocusID (NCBI) 2537
Atlas_Id 53345
Location 1p35.3  [Link to chromosome band 1p35]
Location_base_pair Starts at 27666061 and ends at 27672213 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IFI6 (1p36.11) / CTNS (17p13.2)IFI6 (1p36.11) / MAFF (22q13.1)IFI6 (1p36.11) / PRSS8 (16p11.2)
IFI6 (1p36.11) / SERINC1 (6q22.31)IFI6 (1p36.11) / STPG1 (1p36.11)IFI6 (1p36.11) / TNRC18 (7p22.1)
IFI6 1p36.11 C1orf201

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)IFI6   4054
Cards
Entrez_Gene (NCBI)IFI6  2537  interferon alpha inducible protein 6
Aliases6-16; FAM14C; G1P3; IFI-6-16; 
IFI616
GeneCards (Weizmann)IFI6
Ensembl hg19 (Hinxton)ENSG00000126709 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000126709 [Gene_View]  chr1:27666061-27672213 [Contig_View]  IFI6 [Vega]
ICGC DataPortalENSG00000126709
TCGA cBioPortalIFI6
AceView (NCBI)IFI6
Genatlas (Paris)IFI6
WikiGenes2537
SOURCE (Princeton)IFI6
Genetics Home Reference (NIH)IFI6
Genomic and cartography
GoldenPath hg38 (UCSC)IFI6  -     chr1:27666061-27672213 -  1p35.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)IFI6  -     1p35.3   [Description]    (hg19-Feb_2009)
EnsemblIFI6 - 1p35.3 [CytoView hg19]  IFI6 - 1p35.3 [CytoView hg38]
Mapping of homologs : NCBIIFI6 [Mapview hg19]  IFI6 [Mapview hg38]
OMIM147572   
Gene and transcription
Genbank (Entrez)AF430686 AK024814 AK314488 BC011601 BC015603
RefSeq transcript (Entrez)NM_002038 NM_022872 NM_022873
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)IFI6
Cluster EST : UnigeneHs.730125 [ NCBI ]
CGAP (NCI)Hs.730125
Alternative Splicing GalleryENSG00000126709
Gene ExpressionIFI6 [ NCBI-GEO ]   IFI6 [ EBI - ARRAY_EXPRESS ]   IFI6 [ SEEK ]   IFI6 [ MEM ]
Gene Expression Viewer (FireBrowse)IFI6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)2537
GTEX Portal (Tissue expression)IFI6
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09912   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09912  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09912
Splice isoforms : SwissVarP09912
PhosPhoSitePlusP09912
Domains : Interpro (EBI)IFI6/IFI27   
Domain families : Pfam (Sanger)Ifi-6-16 (PF06140)   
Domain families : Pfam (NCBI)pfam06140   
Conserved Domain (NCBI)IFI6
DMDM Disease mutations2537
Blocks (Seattle)IFI6
SuperfamilyP09912
Human Protein AtlasENSG00000126709
Peptide AtlasP09912
HPRD00959
IPIIPI00018296   IPI00220650   IPI00220651   
Protein Interaction databases
DIP (DOE-UCLA)P09912
IntAct (EBI)P09912
FunCoupENSG00000126709
BioGRIDIFI6
STRING (EMBL)IFI6
ZODIACIFI6
Ontologies - Pathways
QuickGOP09912
Ontology : AmiGOrelease of cytochrome c from mitochondria  protein binding  mitochondrion  plasma membrane  immune response  integral component of membrane  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of mitochondrial depolarization  type I interferon signaling pathway  negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  
Ontology : EGO-EBIrelease of cytochrome c from mitochondria  protein binding  mitochondrion  plasma membrane  immune response  integral component of membrane  negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  negative regulation of mitochondrial depolarization  type I interferon signaling pathway  negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  
NDEx NetworkIFI6
Atlas of Cancer Signalling NetworkIFI6
Wikipedia pathwaysIFI6
Orthology - Evolution
OrthoDB2537
GeneTree (enSembl)ENSG00000126709
Phylogenetic Trees/Animal Genes : TreeFamIFI6
HOVERGENP09912
HOGENOMP09912
Homologs : HomoloGeneIFI6
Homology/Alignments : Family Browser (UCSC)IFI6
Gene fusions - Rearrangements
Fusion : MitelmanIFI6/STPG1 [1p36.11/1p36.11]  
Fusion: TCGAIFI6 1p36.11 C1orf201 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerIFI6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)IFI6
dbVarIFI6
ClinVarIFI6
1000_GenomesIFI6 
Exome Variant ServerIFI6
ExAC (Exome Aggregation Consortium)IFI6 (select the gene name)
Genetic variants : HAPMAP2537
Genomic Variants (DGV)IFI6 [DGVbeta]
DECIPHERIFI6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisIFI6 
Mutations
ICGC Data PortalIFI6 
TCGA Data PortalIFI6 
Broad Tumor PortalIFI6
OASIS PortalIFI6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICIFI6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDIFI6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch IFI6
DgiDB (Drug Gene Interaction Database)IFI6
DoCM (Curated mutations)IFI6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)IFI6 (select a term)
intoGenIFI6
Cancer3DIFI6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM147572   
Orphanet
MedgenIFI6
Genetic Testing Registry IFI6
NextProtP09912 [Medical]
TSGene2537
GENETestsIFI6
Target ValidationIFI6
Huge Navigator IFI6 [HugePedia]
snp3D : Map Gene to Disease2537
BioCentury BCIQIFI6
ClinGenIFI6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD2537
Chemical/Pharm GKB GenePA28466
Clinical trialIFI6
Miscellaneous
canSAR (ICR)IFI6 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineIFI6
EVEXIFI6
GoPubMedIFI6
iHOPIFI6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:03:39 CEST 2017

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